نتائج البحث

Determinants of chemoselectivity in ubiquitination by the J2 family of ubiquitin-conjugating enzymes.

• Authors : Swarnkar, Anuruti¹ (AUTHOR); Leidner, Florian² (AUTHOR); Rout, Ashok K^3,4 (AUTHOR)

Subjects: *UBIQUITIN-conjugating enzymes; *LIFE sciences; *BINDING sites

• Source: EMBO Journal. Dec2024, Vol. 43 Issue 24, p6705-6739. 35p.

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Echinococcus granulosus ubiquitin-conjugating enzymes (E2D2 and E2N) promote the formation of liver fibrosis in TGFβ1-induced LX-2 cells.

• Authors : Du, Xiaodi¹ (AUTHOR); Hua, Ruiqi¹ (AUTHOR); He, Xue¹ (AUTHOR)

• Source: Parasites & Vectors. 4/20/2024, Vol. 17 Issue 1, p1-13. 13p.

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E2 Ubiquitin-Conjugating Enzymes Regulates Dengue Virus-2 Replication in Aedes albopictus

• Authors : Wang, Jiaqi; Zheng, Xueli; Wang, Xuexue

Subjects: Medical Microbiology; Biomedical and Clinical Sciences; Biological Sciences

• Source: Microorganisms. 12(12)

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The ubiquitin-conjugating enzyme UBE2D maintains a youthful proteome and ensures protein quality control during aging by sustaining proteasome activity.

• Authors : Hunt, Liam C.¹ (AUTHOR); Curley, Michelle¹ (AUTHOR); Nyamkondiwa, Kudzai¹ (AUTHOR)

• Source: PLoS Biology. 1/29/2025, Vol. 23 Issue 1, p1-31. 31p.

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E2 Ubiquitin-Conjugating Enzymes Regulates Dengue Virus-2 Replication in Aedes albopictus

• Authors : Jiaqi Wang; Xueli Zheng; Xuexue Wang

Subjects: E2 ubiquitin-conjugating enzymes; SUMOylation; regulates

• Source: Microorganisms, Vol 12, Iss 12, p 2508 (2024)

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Proteome Profiling of S. cerevisiae Strains Lacking the Ubiquitin-Conjugating Enzymes Ubc4 and Ubc5 During Exponential Growth and After Heat Shock Treatment

• Authors : Valentina Rossio; Xinyue Liu; Joao A. Paulo

Subjects: TMT proteomics; ubiquitin–proteasome system; S. cerevisiae

• Source: Microorganisms, Vol 12, Iss 11, p 2235 (2024)

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Arabidopsis Ubiquitin-Conjugating Enzymes UBC4, UBC5, and UBC6 Have Major Functions in Sugar Metabolism and Leaf Senescence.

• Authors : Wang, Sheng^1,2 (AUTHOR); Cao, Ling² (AUTHOR); Willick, Ian R.¹ (AUTHOR)

Subjects: *UBIQUITIN-conjugating enzymes; *ARABIDOPSIS; *SUGAR

• Source: International Journal of Molecular Sciences. Oct2022, Vol. 23 Issue 19, p11143. 21p.

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Interfering with UBE2L3 expression targets regulation of MLKL to promote necroptosis inhibition of growth in osteosarcoma.

• Authors : Zhao X; Department of Traumatic Orthopedics, The Second Hospital of Shandong University, Jinan, 250033, China.; Department of Traumatic Orthopedics, Shandong Second Provincial General Hospital, Jinan, 250022, China.

Subjects: Osteosarcoma*/Osteosarcoma*/Osteosarcoma*/pathology ; Osteosarcoma*/Osteosarcoma*/Osteosarcoma*/metabolism ; Ubiquitin-Conjugating Enzymes*/Ubiquitin-Conjugating Enzymes*/Ubiquitin-Conjugating Enzymes*/metabolism

• Source: World journal of surgical oncology [World J Surg Oncol] 2025 Feb 24; Vol. 23 (1), pp. 63. Date of Electronic Publication: 2025 Feb 24.Publisher: BioMed Central Country of Publication: England NLM ID: 101170544 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-7819

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Identification of UBE2N as a biomarker of Alzheimer's disease by combining WGCNA with machine learning algorithms.

• Authors : Feng G; Key Laboratory of Bioresource Research and Development of Liaoning Province, College of Life and Health Sciences, Northeastern University, Shenyang, China.; Zhong M

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/diagnosis

• Source: Scientific reports [Sci Rep] 2025 Feb 22; Vol. 15 (1), pp. 6479. Date of Electronic Publication: 2025 Feb 22.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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RHEB neddylation by the UBE2F-SAG axis enhances mTORC1 activity and aggravates liver tumorigenesis.

• Authors : Zhang F; Cancer Institute, The Second Affiliated Hospital, Zhejiang University School of Medicine, 310009, Hangzhou, China.; Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, 310009, Hangzhou, China.

Subjects: Ubiquitin-Conjugating Enzymes*/Ubiquitin-Conjugating Enzymes*/Ubiquitin-Conjugating Enzymes*/metabolism ; Ubiquitin-Conjugating Enzymes*/Ubiquitin-Conjugating Enzymes*/Ubiquitin-Conjugating Enzymes*/genetics ; Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism

• Source: The EMBO journal [EMBO J] 2025 Feb; Vol. 44 (4), pp. 1185-1219. Date of Electronic Publication: 2025 Jan 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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