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Insight into the Structure of the Neutral Amino Acid Transporter B0AT2 Enabled the Discovery of Tiagabine as an Inhibitor

• Authors : Jędrzej Kukułowicz; Agata Siwek; Małgorzata Wolak

• Source: ACS Chemical Neuroscience. 16:262-274

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Cryo-EM structure of ACE2-SIT1 in complex with tiagabine

• Authors : Angelika Bröer; Ziwei Hu; Jędrzej Kukułowicz

Subjects: Xenopus laevis; Binding Sites; Amino Acid Transport Systems, Neutral

• Source: J Biol Chem

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Neurosteroid replacement therapy using tiagabine and zuranolone restores cerebellar neurodevelopment and reduces hyperactive behaviour following preterm birth

• Authors : Carlton L. Pavy; Julia C. Shaw; Hannah K. Palliser

• Source: Journal of Developmental Origins of Health and Disease. 16

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Neuroprotective activities of sertraline, tiagabine, and bicifadine with autophagy-inducing potentials in a 6-hydroxidopamine-treated Parkinson’s disease cell model

• Authors : Chaemi Lee; Seong Soon Kim; Myung Ae Bae

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Tiagabine-induced encephalopathy suppressed by vagus nerve stimulation: A case report

• Authors : Christine N. Smith; Stephan Eisenschenk; Yue Wang

Subjects: Case report; Encephalopathy; Tiagabine

• Source: Epilepsy & Behavior Reports, Vol 28, Iss , Pp 100709- (2024)

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Tiagabine induced modulation of oscillatory connectivity and activity match PET-derived, canonical GABA-A receptor distributions

• Authors : Shaw, Alexander D.; Chandler, Hannah L.; Hamandi, Khalid

Subjects: Mammals; 0301 basic medicine; Receptor-mapping

• Source: Eur Neuropsychopharmacol

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Antiepileptic Drug Tiagabine Does Not Directly Target Key Cardiac Ion Channels Kv11.1, Nav1.5 and Cav1.2.

• Authors : Kowalska M; Department of Organic Chemistry, Faculty of Pharmacy, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 87-100 Toruń, Poland.; Fijałkowski Ł

Subjects: Calcium Channels, L-Type/Calcium Channels, L-Type/Calcium Channels, L-Type/*chemistry ; ERG1 Potassium Channel/ERG1 Potassium Channel/ERG1 Potassium Channel/*antagonists & inhibitors ; Epilepsy/Epilepsy/Epilepsy/*drug therapy

• Source: Molecules (Basel, Switzerland) [Molecules] 2021 Jun 09; Vol. 26 (12). Date of Electronic Publication: 2021 Jun 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Molecular Dynamic Simulations to Probe Stereoselectivity of Tiagabine Binding with Human GAT1.

• Authors : Zafar S; Research Center for Modeling and Simulation (RCMS), National University of Sciences and Technology (NUST), Islamabad 44000, Pakistan.; Jabeen I

Subjects: GABA Agents/GABA Agents/GABA Agents/*chemistry ; GABA Plasma Membrane Transport Proteins/GABA Plasma Membrane Transport Proteins/GABA Plasma Membrane Transport Proteins/*chemistry ; Tiagabine/Tiagabine/Tiagabine/*chemistry

• Source: Molecules (Basel, Switzerland) [Molecules] 2020 Oct 16; Vol. 25 (20). Date of Electronic Publication: 2020 Oct 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Tiagabine and zonisamide differentially regulate the glial properties in an astrocyte-microglia co-culture model of inflammation

• Authors : Fatme Seval Ismail; Pedro M. Faustmann; Eckart Förster

Subjects: Research

• Source: Naunyn Schmiedebergs Arch Pharmacol

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Tiagabine Incorporated Polymeric Microneedles: Formulation and Characterization Studies

• Authors : Kadir Aykaç; Ebru Başaran

Subjects: 0301 basic medicine; 03 medical and health sciences; 3. Good health

• Source: Current Applied Polymer Science. 6:48-60

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