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Academic Journal

Perinuclear positioning of endosomes can affect PS-ASO activities.

  • Authors : Liang XH; Core Antisense Research, Ionis Pharmaceuticals, Inc., Carlsbad, CA 92010, USA.; Nichols JG

Subjects: Cell Nucleus/Cell Nucleus/Cell Nucleus/*metabolism ; Endosomes/Endosomes/Endosomes/*metabolism ; Oligonucleotides, Antisense/Oligonucleotides, Antisense/Oligonucleotides, Antisense/*metabolism

  • Source: Nucleic acids research [Nucleic Acids Res] 2021 Dec 16; Vol. 49 (22), pp. 12970-12985.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Nucleotides-Induced Changes in the Mechanical Properties of Living Endothelial Cells and Astrocytes, Analyzed by Atomic Force Microscopy.

  • Authors : Gil-Redondo JC; Departamento de Bioquímica y Biología Molecular, Facultad de Veterinaria, Instituto Universitario de Investigación en Neuroquímica (IUIN), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdiSSC), Universidad Complutense Madrid, 28040 Madrid, Spain.; Department of Nanobiotechnology (DNBT), Institute for Biophysics, BOKU University for Natural Resources and Life Sciences, Muthgasse 11 (Simon Zeisel Haus), A-1190 Vienna, Austria.

Subjects: Adenosine Diphosphate/Adenosine Diphosphate/Adenosine Diphosphate/*analogs & derivatives ; Astrocytes/Astrocytes/Astrocytes/*metabolism ; Human Umbilical Vein Endothelial Cells/Human Umbilical Vein Endothelial Cells/Human Umbilical Vein Endothelial Cells/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Jan 10; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 10.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Novel Iodine-induced Cleavage Real-time PCR Assay for Accurate Quantification of Phosphorothioate Modified Sites in Bacterial DNA.

  • Authors : Chen Y; State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, and School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, 200030, China.; Zheng T

Subjects: DNA, Bacterial/DNA, Bacterial/DNA, Bacterial/*chemistry ; Real-Time Polymerase Chain Reaction/Real-Time Polymerase Chain Reaction/Real-Time Polymerase Chain Reaction/*methods ; Thionucleotides/Thionucleotides/Thionucleotides/*analysis

  • Source: Scientific reports [Sci Rep] 2019 May 16; Vol. 9 (1), pp. 7485. Date of Electronic Publication: 2019 May 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Importance of 6-Thioguanine Nucleotide Metabolite Monitoring in Inflammatory Bowel Disease Patients Treated with Azathioprine.

  • Authors : Pavlovska K; Department of Preclinical and Clinical Pharmacology and Toxicology, Medical faculty, Skopje, Republic of Macedonia.; Petrushevska M

Subjects: Azathioprine/Azathioprine/Azathioprine/*adverse effects ; Guanine Nucleotides/Guanine Nucleotides/Guanine Nucleotides/*metabolism ; Immunosuppressive Agents/Immunosuppressive Agents/Immunosuppressive Agents/*adverse effects

  • Source: Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki) [Pril (Makedon Akad Nauk Umet Odd Med Nauki)] 2019 May 01; Vol. 40 (1), pp. 73-79.Publisher: Makedonska akademija na naukite i umetnostite Country of Publication: North Macedonia NLM ID: 101677081 Publication Model: Print Cited Medium:

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Editorial & Opinion

The End of the Dosage of 6-Thioguanine Nucleotides? Not so Sure….

  • Authors : Roblin X; Department of Gastroenterology, University Hospital of Saint Etienne, Saint Etienne, France.; Paul S

Subjects: Dose-Response Relationship, Drug* ; Guanine Nucleotides*/Guanine Nucleotides*/Guanine Nucleotides*/administration & dosage ; Guanine Nucleotides*/Guanine Nucleotides*/Guanine Nucleotides*/blood

  • Source: Journal of Crohn's & colitis [J Crohns Colitis] 2018 Jan 05; Vol. 12 (1), pp. 126.Publisher: Oxford University Press Country of Publication: England NLM ID: 101318676 Publication Model: Print Cited Medium: Internet ISSN:

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Editorial & Opinion

Response to 'The end of the dosage of 6 Thioguanine nucleotides? Not so sure…'.

  • Authors : Waljee AK; Department of Veterans Affairs Center for Clinical Management Research, Ann Arbor, MI, USA.; Division of Gastroenterology, Department of Internal Medicine, University of Michigan, MI, USA.

Subjects: Guanine Nucleotides*/Guanine Nucleotides*/Guanine Nucleotides*/administration & dosage ; Guanine Nucleotides*/Guanine Nucleotides*/Guanine Nucleotides*/pharmacokinetics ; Thionucleotides*/Thionucleotides*/Thionucleotides*/administration & dosage

  • Source: Journal of Crohn's & colitis [J Crohns Colitis] 2018 Jan 05; Vol. 12 (1), pp. 127.Publisher: Oxford University Press Country of Publication: England NLM ID: 101318676 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Thionucleotides as inhibitors of ribonucleotide reductase.

  • Authors : Roy B; Institut de Biochimie Biophysique Moléculaire et Cellulaire, Université de Paris Sud, UMR CNRS 8619, Orsay, France.; Chambert S

Subjects: Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*chemical synthesis ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology ; Ribonucleotide Reductases/Ribonucleotide Reductases/Ribonucleotide Reductases/*antagonists & inhibitors

  • Source: Nucleosides, nucleotides & nucleic acids [Nucleosides Nucleotides Nucleic Acids] 2003 May-Aug; Vol. 22 (5-8), pp. 883-5.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 100892832 Publication Model: Print Cited Medium: Print ISSN: 1525-7770

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Academic Journal

Evidence for a PI3-kinase independent pathway in the regulation of Rap1b activation downstream of the P2Y12 receptor in platelets.

  • Authors : Dangelmaier C; Sol Sherry Thrombosis Research Center and the Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.; Kunapuli SP

Subjects: Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/metabolism ; Receptors, Purinergic P2*/Receptors, Purinergic P2*/Receptors, Purinergic P2*/metabolism; Adenosine Diphosphate/Adenosine Diphosphate/Adenosine Diphosphate/analogs & derivatives

  • Source: Platelets [Platelets] 2022 Nov 17; Vol. 33 (8), pp. 1301-1306. Date of Electronic Publication: 2022 May 06.Publisher: Informa Healthcare Country of Publication: England NLM ID: 9208117 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Chronological attenuation of NPRA/PKG/AMPK signaling promotes vascular aging and elevates blood pressure.

  • Authors : Long C; Vascular Function Laboratory, Human Aging Research Institute and School of Life Science, Nanchang university, and Jiangxi Key Laboratory of Human Aging, Nanchang, China.; Liu H

Subjects: AMP-Activated Protein Kinases*/AMP-Activated Protein Kinases*/AMP-Activated Protein Kinases*/metabolism ; Hypertension*/Hypertension*/Hypertension*/genetics ; Hypertension*/Hypertension*/Hypertension*/metabolism

  • Source: Aging cell [Aging Cell] 2022 Sep; Vol. 21 (9), pp. e13699. Date of Electronic Publication: 2022 Aug 25.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 ل  922 نتائج ل ""Thionucleotides""