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  • 1-10 ل  5,699 نتائج ل ""Succinates""
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Academic Journal

4-Octyl itaconate attenuates renal tubular injury in db/db mice by activating Nrf2 and promoting PGC-1α-mediated mitochondrial biogenesis.

  • Authors : Shao M; Department of Endocrinology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Research Center for Metabolic and Cardiovascular Diseases, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Subjects: Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha*/Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha*/Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha*/metabolism ; NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/metabolism ; Succinates*/Succinates*/Succinates*/pharmacology

  • Source: Renal failure [Ren Fail] 2024 Dec; Vol. 46 (2), pp. 2403653. Date of Electronic Publication: 2024 Sep 18.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

4-Octyl itaconate blocks GSDMB-mediated pyroptosis and restricts inflammation by inactivating granzyme A.

  • Authors : Gong W; Department of General Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.; Fu H

Subjects: Pyroptosis*/Pyroptosis*/Pyroptosis*/drug effects ; Succinates*/Succinates*/Succinates*/pharmacology ; Succinates*/Succinates*/Succinates*/metabolism

  • Source: Cell proliferation [Cell Prolif] 2024 Dec; Vol. 57 (12), pp. e13711. Date of Electronic Publication: 2024 Jul 09.Publisher: Published for the Cell Kinetics Society, the European Study Group for Cell Proliferation, and the International Cell Cycle Society by Blackwell Scientific Publications

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Academic Journal

IRG1/itaconate enhances efferocytosis by activating Nrf2-TIM4 signaling pathway to alleviate con A induced autoimmune liver injury.

  • Authors : Zeng L; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan, 430022, Hubei Province, China.; Wang Y

Subjects: NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/metabolism ; NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/genetics ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects

  • Source: Cell communication and signaling : CCS [Cell Commun Signal] 2025 Feb 05; Vol. 23 (1), pp. 63. Date of Electronic Publication: 2025 Feb 05.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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Academic Journal

The effect of sarpogrelate compared to aspirin in high- or very-high-risk diabetes for primary prevention.

  • Authors : Kang SH; Gachon Medical Research Institute, Gachon Biomedical Convergence Institute, Gachon University Gil Medical Center, College of Medicine, Gachon University, Incheon, 21565, Republic of Korea.; Department of Research and Analysis, National Health Insurance Service Ilsan Hospital, Goyang, 10444, Republic of Korea.

Subjects: Aspirin*/Aspirin*/Aspirin*/therapeutic use ; Aspirin*/Aspirin*/Aspirin*/adverse effects ; Succinates*/Succinates*/Succinates*/therapeutic use

  • Source: Scientific reports [Sci Rep] 2025 Jan 29; Vol. 15 (1), pp. 3616. Date of Electronic Publication: 2025 Jan 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Chicoric acid advanced PAQR3 ubiquitination to ameliorate ferroptosis in diabetes nephropathy through the relieving of the interaction between PAQR3 and P110α pathway.

  • Authors : Zhang W; Department of Pharmacy, Second Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, P. R. China.; Liu Y

Subjects: Caffeic Acids* ; Diabetes Mellitus* ; Diabetic Nephropathies*/Diabetic Nephropathies*/Diabetic Nephropathies*/drug therapy

  • Source: Clinical and experimental hypertension (New York, N.Y. : 1993) [Clin Exp Hypertens] 2024 Dec 31; Vol. 46 (1), pp. 2326021. Date of Electronic Publication: 2024 Mar 25.Publisher: Informa Healthcare Country of Publication: England NLM ID: 9305929 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Enhanced itaconic acid secretion from macrophages mediates the protection of mesenchymal stem cell-derived exosomes on lipopolysaccharide-induced acute lung injury mice.

  • Authors : Wen Y; Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, No. 37, Guoxue Lane, Wuhou District, Chengdu, 610000, Sichuan, China.; Department of Respiratory and Critical Care Medicine, Chengdu Second People's Hospital, Chengdu, 610000, Sichuan, China.

Subjects: Acute Lung Injury*/Acute Lung Injury*/Acute Lung Injury*/chemically induced ; Acute Lung Injury*/Acute Lung Injury*/Acute Lung Injury*/therapy ; Acute Lung Injury*/Acute Lung Injury*/Acute Lung Injury*/metabolism

  • Source: Biology direct [Biol Direct] 2024 Dec 26; Vol. 19 (1), pp. 138. Date of Electronic Publication: 2024 Dec 26.Publisher: BioMed Central Country of Publication: England NLM ID: 101258412 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6150

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Academic Journal

Cancer cell-intrinsic biosynthesis of itaconate promotes tumor immunogenicity.

  • Authors : Wang Z; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.; Cui L

Subjects: Succinates*/Succinates*/Succinates*/pharmacology ; Succinates*/Succinates*/Succinates*/metabolism ; Carboxy-Lyases*/Carboxy-Lyases*/Carboxy-Lyases*/metabolism

  • Source: The EMBO journal [EMBO J] 2024 Nov; Vol. 43 (22), pp. 5530-5547. Date of Electronic Publication: 2024 Sep 30.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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