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  • 1-10 ل  308 نتائج ل ""Sterol 14-Demethylase""

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Academic Journal

Sterol 14-alpha demethylase (CYP51) activity in Leishmania donovani is likely dependent upon cytochrome P450 reductase 1.

  • Authors : Tulloch LB; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dow Street, Dundee, United Kingdom.; Tinti M

Subjects: Leishmania donovani*/Leishmania donovani*/Leishmania donovani*/enzymology ; Drug Resistance* ; Sterol 14-Demethylase*/Sterol 14-Demethylase*/Sterol 14-Demethylase*/metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2024 Jul 11; Vol. 20 (7), pp. e1012382. Date of Electronic Publication: 2024 Jul 11 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

The Computational Interaction Analyses of Some Vitamin D-Related Compounds with Sterol 14-Demethylase (CYP51) – Could It Be a Glimmer of Hope to Find New Anti-Mucormycotic Drugs Extracted from Plants-Derived Sterols?

Subjects: Complementary and alternative medicine; Plant Science; Drug Discovery

  • Source: Natural Product Communications ; volume 19, issue 1 ; ISSN 1934-578X 1555-9475

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Academic Journal

Mechanistic Insights into Stereospecific Antifungal Activity of Chiral Fungicide Prothioconazole against Fusarium oxysporum F. sp. cubense .

  • Authors : Yang X; Key Laboratory of Tropical and Subtropical Fruit Tree Research of Guangdong Province, Institution of Fruit Tree Research, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.; College of Horticulture, Sichuan Agricultural University, Chengdu 611130, China.

Subjects: Oxidative Stress*; Antifungal Agents/Antifungal Agents/Antifungal Agents/*pharmacology ; Fusarium/Fusarium/Fusarium/*drug effects Fusarium oxysporum

  • Source: International journal of molecular sciences [Int J Mol Sci] 2022 Feb 21; Vol. 23 (4). Date of Electronic Publication: 2022 Feb 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

K143R Amino Acid Substitution in 14-α-Demethylase (Erg11p) Changes Plasma Membrane and Cell Wall Structure of Candida albicans .

  • Authors : Derkacz D; Department of Biotransformation, Faculty of Biotechnology, University of Wroclaw, 50-383 Wroclaw, Poland.; Bernat P

Subjects: Amino Acid Substitution* ; Drug Resistance, Fungal*; Candida albicans/Candida albicans/Candida albicans/*growth & development

  • Source: International journal of molecular sciences [Int J Mol Sci] 2022 Jan 31; Vol. 23 (3). Date of Electronic Publication: 2022 Jan 31.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Point mutations in the squalene epoxidase erg1 and sterol 14-α demethylase erg11 gene of T indotineae isolates indicate that the resistant mutant strains evolved independently.

  • Authors : Burmester A; Department of Dermatology, University Hospital Jena, Jena, Germany.; Hipler UC

Subjects: Drug Resistance, Fungal*/Drug Resistance, Fungal*/Drug Resistance, Fungal*/genetics ; Point Mutation* ; Squalene Monooxygenase*/Squalene Monooxygenase*/Squalene Monooxygenase*/genetics

  • Source: Mycoses [Mycoses] 2022 Jan; Vol. 65 (1), pp. 97-102. Date of Electronic Publication: 2021 Nov 16.Publisher: Grosse Verlag Country of Publication: Germany NLM ID: 8805008 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Promising Antileishmanial Activity of Micromeria nervosa Essential Oil: In Vitro and In Silico Studies.

  • Authors : Essid R; Laboratory of Bioactive Substances, Biotechnology Center of Borj Cedria, BP 901, Hammam-Lif 2050, Tunisia.; University of Tunis-El Manar, Campus Universitaire Farhat Hached, BP-94 Rommana, Tunis 1068, Tunisia.

Subjects: Oils, Volatile*/Oils, Volatile*/Oils, Volatile*/pharmacology ; Oils, Volatile*/Oils, Volatile*/Oils, Volatile*/chemistry ; Antiprotozoal Agents*/Antiprotozoal Agents*/Antiprotozoal Agents*/pharmacology

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Apr 19; Vol. 29 (8). Date of Electronic Publication: 2024 Apr 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Effects of Y132H and F145L Substitutions on the Activity, Azole Resistance and Spectral Properties of Candida albicans Sterol 14-Demethylase P450 (CYP51): A Live Example Showing the Selection of Altered P450 through Interaction with ...

Subjects: *CANDIDA albicans; *AMINO acids; *AZOLES

  • Source: Journal of Biochemistry. May2005, Vol. 137 Issue 5, p625-632. 8p.

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Academic Journal

The Amino Acid Residues Affecting the Activity and Azole Susceptibility of Rat CYP51 (Sterol 14-Demethylase P450).

Subjects: *AMINO acids; *KETOCONAZOLE; *ESCHERICHIA coli

  • Source: Journal of Biochemistry. 2001, Vol. 129 Issue 5, p761-768. 8p.

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Academic Journal

Synthesis, Characterization and Biological Evaluation of New 3,5-Disubstituted-Pyrazoline Derivatives as Potential Anti- Mycobacterium tuberculosis H37Ra Compounds.

  • Authors : Wong KT; School of Chemical Sciences, Universiti Sains Malaysia, Minden, Penang 11800, Malaysia.; Osman H

Subjects: 14-alpha Demethylase Inhibitors/14-alpha Demethylase Inhibitors/14-alpha Demethylase Inhibitors/*chemical synthesis ; Antitubercular Agents/Antitubercular Agents/Antitubercular Agents/*chemical synthesis ; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*antagonists & inhibitors

  • Source: Molecules (Basel, Switzerland) [Molecules] 2021 Apr 05; Vol. 26 (7). Date of Electronic Publication: 2021 Apr 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Purification and Characterization of Rat Sterol 14-Demethylase P450 (CYP51) Expressed in Escherichia coli.

Subjects: *ESCHERICHIA coli; *AMINO acid analysis; *AMINO acid sequence

  • Source: Journal of Biochemistry. 1999, Vol. 126 Issue 5, p927-933. 7p.

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  • 1-10 ل  308 نتائج ل ""Sterol 14-Demethylase""