نتائج البحث

Tryptophan regulates the expression of IGFBP1 in bovine endometrial epithelial cells in vitro via the TDO2-AHR pathway

• Authors : Wang, Peng-Chao; Liu, Ze-Kun; Li, Jia-Rong

Subjects: Animals; Cattle; Female

• Source: BMC Veterinary Research. 20:1-9

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Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3

• Authors : Daams, Renée; Tran, Thi Thu Phuong; Jemaà, Mohamed

Subjects: Humans; B-Cell Lymphoma 3 Protein/metabolism; Apoptosis/drug effects

• Source: Cell Death & Disease eSSENCE: The e-Science Collaboration EpiHealth: Epidemiology for Health StemTherapy: National Initiative on Stem Cells for Regenerative Therapy. 15(9)

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Targeting undruggable phosphatase overcomes trastuzumab resistance by inhibiting multi-oncogenic kinases

• Authors : Wang, Lu; Lin, Yusheng; Yao, Zhimeng

Subjects: Trastuzumab/pharmacology; Humans; Drug Resistance

• Source: Wang , L , Lin , Y , Yao , Z , Babu , N , Lin , W , Chen , C , Du , L , Cai , S , Pan , Y , Xiong , X , Ye , Q , Ren , H , Zhang , D , Chen , Y , Yeung , S-C J , Bremer , E & Zhang , H 2024 , '

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Butyrate and propionate are microbial danger signals that activate the NLRP3 inflammasome in human macrophages upon TLR stimulation

• Authors : Wang, Wei; Dernst, Alesja; Martin, Bianca

Subjects: Humans; NLR Family; Pyrin Domain-Containing 3 Protein/metabolism

• Source: Wang , W , Dernst , A , Martin , B , Lorenzi , L , Cadefau-Fabregat , M , Phulphagar , K , Wagener , A , Budden , C , Stair , N , Wagner , T , Färber , H , Jaensch , A , Stahl , R , Duthie , F ,

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A SRC-slug-TGFβ2 signaling axis drives poor outcomes in triple-negative breast cancers

• Authors : Angel, Charlotte Zoe; Beattie, Shannon; Hanif, Ezanee Azlina Mohamad

Subjects: Triple Negative Breast Neoplasms/genetics; Humans; Signal Transduction/drug effects

• Source: Angel , C Z , Beattie , S , Hanif , E A M , Ryan , M P , Guerra Liberal , F D C , Zhang , S-D , Monteith , S , Buckley , N E , Parker , E , Haynes , S , McIntyre , A J , Haddock , P , Sharifova , M ,

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Fibrotic response to anti-CSF-1R therapy potentiates glioblastoma recurrence.

• Authors : Watson, S.S.; Zomer, A.; Fournier, N.

Subjects: Glioblastoma/drug therapy; Glioblastoma/pathology; Animals

• Source: Cancer cell, vol. 42, no. 9, pp. 1507-1527.e11

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25-Hydroxycholesterol attenuates tumor necrosis factor alpha-induced blood-brain barrier breakdown in vitro.

• Authors : Loiola, R.A.; Nguyen, C.; Dib, S.

Subjects: Hydroxycholesterols/pharmacology; Hydroxycholesterols/metabolism; Blood-Brain Barrier/metabolism

• Source: Biochimica et biophysica acta. Molecular basis of disease, vol. 1870, no. 8, pp. 167479

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Amelioration of Fibrosis via S1P Inhibition Is Regulated by Inactivation of TGF-beta and SPL Pathways in the Human Cornea

• Authors : Nicholas, Sarah E.; Basu, Sandip K.; Mandal, Nawajes

Subjects: LTBP; S1P; SMAD

• Source: International Journal of Molecular Sciences

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Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways

• Authors : Kurmasheva, Naziia; Said, Aida; Wong, Boaz

Subjects: Animals; Humans; Oncolytic Virotherapy/methods

• Source: Kurmasheva , N , Said , A , Wong , B , Kinderman , P , Han , X , Rahimic , A H F , Kress , A , Carter-Timofte , M E , Holm , E , van der Horst , D , Kollmann , C F , Liu , Z , Wang , C , Hoang , H-D ,

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Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells

• Authors : Evan R Abt; Thuc M Le; Amanda M Dann

Subjects: Adenocarcinoma / metabolism; Adenocarcinoma / pathology; Animals

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