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The Anti-HIV Effects of Saquinavir Soft Gelatin Capsules Versus Indinavir in Patients Who Have Used Saquinavir Hard Gelatin Capsules for One Year

• Source: The Antiviral Effect of Switching From Hard Capsule Saquinavir (SQVhc) to the Soft Gelatin Capsule of Saquinavir (SQVsc) Versus Switching

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Enhanced antifungal activity of posaconazole against Candida auris by HIV protease inhibitors, atazanavir and saquinavir.

• Authors : Elgammal, Yehia^1,2 (AUTHOR); Salama, Ehab A.^1,2 (AUTHOR); Seleem, Mohamed N.^1,2 (AUTHOR)

• Source: Scientific Reports. 1/18/2024, Vol. 13 Issue 1, p1-8. 8p.

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Revamped role for approved drug: integrative computational and biophysical analysis of saquinavir's peptidyl arginine deiminase 4 inhibition for rheumatoid arthritis.

• Authors : Thirugnanasambandham I; Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, Nilgiris, Tamil Nadu, India.; Jupudi S

Subjects: Arthritis, Rheumatoid*/Arthritis, Rheumatoid*/Arthritis, Rheumatoid*/drug therapy ; Arthritis, Rheumatoid*/Arthritis, Rheumatoid*/Arthritis, Rheumatoid*/enzymology ; Protein-Arginine Deiminase Type 4*/Protein-Arginine Deiminase Type 4*/Protein-Arginine Deiminase Type 4*/antagonists & inhibitors

• Source: The Biochemical journal [Biochem J] 2024 Oct 16; Vol. 481 (20), pp. 1379-1393.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Safety of Saquinavir and High Doses of Lopinavir/Ritonavir in Children With HIV

• Authors : Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

• Source: A Phase I/II Safety, Tolerability, and Pharmacokinetic Study of High Dose Lopinavir/Ritonavir With or Without Saquinavir in HIV-Infected Pediatric Subjects Previously

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The Effects of Staggered Dosing on Interactions Between Paired Combinations of Nelfinavir, Ritonavir, and Saquinavir

• Source: A Prototype Study to Test the Effect of Staggered Dosing on the Pharmacokinetic Interactions Between Paired Combinations of Nelfinavir (NFV), Ritonavir (RTV), and Soft Gelatin Capsule of

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A Study to Compare Two Anti-HIV Combination Therapies Each Containing Saquinavir in HIV-Positive Children

• Source: A Randomized Trial of Two Saquinavir-Containing Combination Treatment Regimens in Children With HIV InfectionBrundage RC, Kline MW, Lindsey J, Fenton T, Fletcher

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Fortovase (Saquinavir) Given With Low-Dose Ritonavir, Zidovudine, and Lamivudine to HIV-Positive Pregnant Women During and After Pregnancy and to Their Newborns

• Authors : Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

• Source: A Phase I Trial of the Safety and Pharmacokinetics of Fortovase (Saquinavir-SGC) Co-Administered With Low Dose (Ritonavir) RTV, ZDV and 3TC in HIV Seropositive Pregnant

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Enhanced antifungal activity of posaconazole against Candida auris by HIV protease inhibitors, atazanavir and saquinavir

• Authors : Yehia Elgammal; Ehab A. Salama; Mohamed N. Seleem

Subjects: Medicine; Science

• Source: Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)

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Saquinavir-Piperine Eutectic Mixture: Preparation, Characterization, and Dissolution Profile.

• Authors : Fandaruff, Cinira¹ (AUTHOR) ; Quirós-Fallas, María Isabel^2,3 (AUTHOR) ; Vega-Baudrit, José Roberto² (AUTHOR)

• Source: Pharmaceutics. Oct2023, Vol. 15 Issue 10, p2446. 15p.

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Liposomal Delivery of Saquinavir to Macrophages Overcomes Cathepsin Blockade by Mycobacterium tuberculosis and Helps Control the Phagosomal Replicative Niches.

• Authors : Pires, David^1,2 (AUTHOR); Mandal, Manoj¹ (AUTHOR); Pinho, Jacinta³ (AUTHOR)

Subjects: *MYCOBACTERIUM tuberculosis; *LATENT infection; *MACROPHAGES

• Source: International Journal of Molecular Sciences. Jan2023, Vol. 24 Issue 2, p1142. 14p.

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