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Predictive Efficacy of Dual Therapies Combining Integrase Strand Transfer Inhibitors with Second-Generation Non-Nucleoside Reverse Transcriptase Inhibitors Following HIV-1 Treatment Failure in Cameroon: Implications for the Use of a Long-Acting Therapeutic Strategy in Low- and Middle-Income Countries

• Authors : Gouissi Anguechia, Davy-Hyacinthe^1,2 (AUTHOR) ; Bouba, Yagai^1,3 (AUTHOR) ; Semengue, Ezechiel Ngoufack Jagni^1,4 (AUTHOR)

Subjects: *NON-nucleoside reverse transcriptase inhibitors; *REVERSE transcriptase inhibitors; *PATIENT compliance

• Source: Viruses (1999-4915). Dec2024, Vol. 16 Issue 12, p1853. 12p.

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Nucleoside Reverse Transcriptase Inhibitors Are the Major Class of HIV Antiretroviral Therapeutics That Induce Neuropathic Pain in Mice.

• Authors : Bush, Keegan¹ (AUTHOR) ; Wairkar, Yogesh^1,2 (AUTHOR) ; Tang, Shao-Jun^1,3 (AUTHOR)

Subjects: *NUCLEOSIDE reverse transcriptase inhibitors; *NON-nucleoside reverse transcriptase inhibitors; *ANTI-HIV agents

• Source: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 16, p9059. 14p.

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A novel application of Kier–Hall electrotopological descriptors in datamining new HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) on the basis of chemical similarity.

• Authors : Gupta, Swagata¹ (AUTHOR); Jain, Nilanjana² (AUTHOR); Sule, Laxmi³ (AUTHOR)

• Source: Journal of Mathematical Chemistry. Nov2024, Vol. 62 Issue 10, p2478-2501. 24p.

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Discovery of Novel Amino Acids (Analogues)-Substituted Thiophene[3,2- d ]pyrimidine Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: Design, Synthesis, and Biological Evaluation.

• Authors : Zhuo, Zongji¹ (AUTHOR) ; Wang, Zhao¹ (AUTHOR) ; Jing, Lanlan¹ (AUTHOR)

Subjects: *NON-nucleoside reverse transcriptase inhibitors; *REVERSE transcriptase; *STRUCTURAL optimization

• Source: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 16, p9028. 12p.

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Safety and Efficacy of a Switch to Doravirine, Tenofovir, Lamivudine (MK-1439A) in Human Immunodeficiency Virus (HIV-1)-Infected Participants Virologically Suppressed on an Anti-retroviral Regimen in Combination With Two Nucleoside Reverse Transcriptase Inhibitors (MK-1439A-024) (DRIVE-SHIFT)

• Source: A Phase III Multicenter, Open-Label, Randomized Study to Evaluate a Switch to MK-1439A in HIV-1-Infected Subjects Virologically Suppressed on a Regimen of a Ritonavir-boosted Protease Inhibitor and

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Profiling the Interaction between Human Serum Albumin and Clinically Relevant HIV Reverse Transcriptase Inhibitors.

• Authors : Costa-Tuna, Andreia¹ (AUTHOR) ; Chaves, Otávio A.^1,2 (AUTHOR) ; Almeida, Zaida L.¹ (AUTHOR)

Subjects: *REVERSE transcriptase inhibitors; *SERUM albumin; *ISOTHERMAL titration calorimetry

• Source: Viruses (1999-4915). Apr2024, Vol. 16 Issue 4, p491. 17p.

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The Application of Prodrugs as a Tool to Enhance the Properties of Nucleoside Reverse Transcriptase Inhibitors.

• Authors : Fernandes, Lívia da Rocha¹ (AUTHOR); Lopes, Juliana Romano¹ (AUTHOR); Bonjorno, Andressa Francielli¹ (AUTHOR)

Subjects: *NUCLEOSIDE reverse transcriptase inhibitors; *PRODRUGS; *ANTIVIRAL agents

• Source: Viruses (1999-4915). Nov2023, Vol. 15 Issue 11, p2234. 34p.

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Clinical benefits of novel non‐nucleoside reverse transcriptase inhibitors: A prospective cohort study.

• Authors : Ma, Shujing¹ (AUTHOR); Xie, Xiaoxin² (AUTHOR); Fu, Yanhua² (AUTHOR)

• Source: Immunity, Inflammation & Disease. Apr2024, Vol. 12 Issue 4, p1-12. 12p.

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Current insights and molecular docking studies of HIV‐1 reverse transcriptase inhibitors.

• Authors : Singh, Ankit Kumar¹ (AUTHOR); Kumar, Adarsh¹ (AUTHOR); Arora, Sahil¹ (AUTHOR)

• Source: Chemical Biology & Drug Design. Jan2024, Vol. 103 Issue 1, p1-21. 21p.

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Reverse transcriptase inhibitors diminish systemic proinflammatory responses to bacterial pathogens

• Authors : Karthik Hullahalli; Katherine G. Dailey; Ryan Acbay

Subjects: reverse transcriptase inhibitors; inflammation; sepsis

• Source: mBio, Vol 16, Iss 2 (2025)

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