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  • 1-10 of  365 نتائج ل ""Receptors, Thrombin""

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Academic Journal

Species Differences in Platelet Protease-Activated Receptors.

  • Authors : Renna SA; Department of Medicine, The Cardeza Foundation for Hematologic Research, Thomas Jefferson University, Philadelphia, PA 19107, USA.; McKenzie SE

Subjects: Receptors, Proteinase-Activated*/Receptors, Proteinase-Activated*/Receptors, Proteinase-Activated*/metabolism ; Receptors, Thrombin*/Receptors, Thrombin*/Receptors, Thrombin*/metabolism; Humans

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 May 05; Vol. 24 (9). Date of Electronic Publication: 2023 May 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

An optimized agonist peptide of protease-activated receptor 4 and its use in a validated platelet-aggregation assay.

  • Authors : Yang J; Research and Development, Bristol Myers Squibb Company, Princeton, NJ, USA.; Mapelli C

Subjects: Receptors, Thrombin* ; Thrombin*/Thrombin*/Thrombin*/pharmacology; Blood Platelets

  • Source: Platelets [Platelets] 2022 Oct 03; Vol. 33 (7), pp. 979-986. Date of Electronic Publication: 2022 Mar 28.Publisher: Informa Healthcare Country of Publication: England NLM ID: 9208117 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

New oral protease-activated receptor 4 antagonist BMS-986120: tolerability, pharmacokinetics, pharmacodynamics, and gene variant effects in humans.

  • Authors : Merali S; Research and Development, Bristol Myers Squibb, Princeton, NJ, USA.; Wang Z

Subjects: Platelet Aggregation* ; Receptors, Thrombin*/Receptors, Thrombin*/Receptors, Thrombin*/genetics; Administration, Oral

  • Source: Platelets [Platelets] 2022 Oct 03; Vol. 33 (7), pp. 969-978. Date of Electronic Publication: 2022 Jun 26.Publisher: Informa Healthcare Country of Publication: England NLM ID: 9208117 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Intravesical CD74 and CXCR4, macrophage migration inhibitory factor (MIF) receptors, mediate bladder pain.

  • Authors : Ye S; Research & Development, Lexington VA Health Care System, Lexington, KY, United States of America.; Ma F

Subjects: Antigens, Differentiation, B-Lymphocyte/Antigens, Differentiation, B-Lymphocyte/Antigens, Differentiation, B-Lymphocyte/*metabolism ; HMGB1 Protein/HMGB1 Protein/HMGB1 Protein/*metabolism ; Histocompatibility Antigens Class II/Histocompatibility Antigens Class II/Histocompatibility Antigens Class II/*metabolism

  • Source: PloS one [PLoS One] 2021 Aug 23; Vol. 16 (8), pp. e0255975. Date of Electronic Publication: 2021 Aug 23 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

PAR-4/Ca 2+ -calpain pathway activation stimulates platelet-derived microparticles in hyperglycemic type 2 diabetes.

  • Authors : Giannella A; Metabolic Disease Unit, Department of Medicine-DIMED, Via Giustiniani, 2, 35128, Padova, Italy.; Ceolotto G

Subjects: Platelet Activation*/Platelet Activation*/Platelet Activation*/drug effects; Blood Glucose/Blood Glucose/Blood Glucose/*metabolism ; Blood Platelets/Blood Platelets/Blood Platelets/*enzymology

  • Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2021 Apr 03; Vol. 20 (1), pp. 77. Date of Electronic Publication: 2021 Apr 03.Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2840

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Academic Journal

Whole blood platelet aggregation determined by the ROTEM platelet equipment; reference intervals and stability.

  • Authors : Nissen PH; Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark.; Skipper MT

Subjects: Receptors, Thrombin*; Adenosine Diphosphate/Adenosine Diphosphate/Adenosine Diphosphate/*pharmacology ; Arachidonic Acid/Arachidonic Acid/Arachidonic Acid/*pharmacology

  • Source: Platelets [Platelets] 2020; Vol. 31 (2), pp. 215-220. Date of Electronic Publication: 2019 Apr 01.Publisher: Informa Healthcare Country of Publication: England NLM ID: 9208117 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

PAR-4 overcomes chemo-resistance in breast cancer cells by antagonizing cIAP1.

  • Authors : Guo H; Institute of Biochemistry and Molecular Biology, Medical School, RWTH Aachen University, 52074, Aachen, Germany.; Clinic for Neuropathlogy, Medical School, RWTH Aachen University, 52074, Aachen, Germany.

Subjects: Drug Resistance, Neoplasm* ; Signal Transduction*; Inhibitor of Apoptosis Proteins/Inhibitor of Apoptosis Proteins/Inhibitor of Apoptosis Proteins/*metabolism

  • Source: Scientific reports [Sci Rep] 2019 Jun 19; Vol. 9 (1), pp. 8755. Date of Electronic Publication: 2019 Jun 19.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Activation of PAR4 Upregulates p16 through Inhibition of DNMT1 and HDAC2 Expression via MAPK Signals in Esophageal Squamous Cell Carcinoma Cells.

  • Authors : Wang M; Department of Human Anatomy, Taishan Medical University, 2 Ying Sheng Dong Lu, Taian 271000, China.; An S

Subjects: Cyclin-Dependent Kinase Inhibitor p16/Cyclin-Dependent Kinase Inhibitor p16/Cyclin-Dependent Kinase Inhibitor p16/*metabolism ; DNA (Cytosine-5-)-Methyltransferase 1/DNA (Cytosine-5-)-Methyltransferase 1/DNA (Cytosine-5-)-Methyltransferase 1/*metabolism ; Esophageal Squamous Cell Carcinoma/Esophageal Squamous Cell Carcinoma/Esophageal Squamous Cell Carcinoma/*metabolism

  • Source: Journal of immunology research [J Immunol Res] 2018 Sep 30; Vol. 2018, pp. 4735752. Date of Electronic Publication: 2018 Sep 30 (Print Publication: 2018).Publisher: Hindawi Publishing Corporation Country of Publication: Egypt NLM ID: 101627166 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

TERT and Akt Are Involved in the Par-4-Dependent Apoptosis of Islet β Cells in Type 2 Diabetes.

  • Authors : Liu C; Endocrine Department, First Affiliated Hospital of the Third Military Medical University (Army Medical University), Chongqing 400038, China.; QiNan W

Subjects: Apoptosis*; Diabetes Mellitus, Experimental/Diabetes Mellitus, Experimental/Diabetes Mellitus, Experimental/*enzymology ; Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/*enzymology

  • Source: Journal of diabetes research [J Diabetes Res] 2018 Aug 14; Vol. 2018, pp. 7653904. Date of Electronic Publication: 2018 Aug 14 (Print Publication: 2018).Publisher: Hindawi Limited Country of Publication: England NLM ID: 101605237 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

Protease-Activated Receptor 4 (PAR4): A Promising Target for Antiplatelet Therapy.

  • Authors : Rwibasira Rudinga G; School of Life Science & Technology, China Pharmaceutical University, 24 Tong Jia Street, Nanjing 210009, China. .; Khan GJ

Subjects: Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*therapeutic use ; Cardiovascular Diseases/Cardiovascular Diseases/Cardiovascular Diseases/*drug therapy ; Platelet Aggregation Inhibitors/Platelet Aggregation Inhibitors/Platelet Aggregation Inhibitors/*therapeutic use

  • Source: International journal of molecular sciences [Int J Mol Sci] 2018 Feb 14; Vol. 19 (2). Date of Electronic Publication: 2018 Feb 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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  • 1-10 of  365 نتائج ل ""Receptors, Thrombin""