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Attempts to Create Transgenic Mice Carrying the Q3924E Mutation in RyR2 Ca 2+ Binding Site.

• Authors : Zhang XH; Cardiac Signaling Center, University of South Carolina, Medical University of South Carolina and Clemson University, Charleston, SC 29425, USA.; Tang FL

Subjects: Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/genetics ; Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/metabolism ; Mice, Transgenic*

• Source: Cells [Cells] 2024 Dec 12; Vol. 13 (24). Date of Electronic Publication: 2024 Dec 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Dual role of the S5 segment in type 1 ryanodine receptor channel gating.

• Authors : Murayama T; Department of Cellular and Molecular Pharmacology, Juntendo University Graduate School of Medicine, Tokyo, 113-8421, Japan. .; Otori Y

Subjects: Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/metabolism ; Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/genetics ; Ion Channel Gating*

• Source: Communications biology [Commun Biol] 2024 Sep 18; Vol. 7 (1), pp. 1108. Date of Electronic Publication: 2024 Sep 18.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Elementary Intracellular Ca Signals are Initiated by a Transition of Release Channel System from a Metastable State

• Authors : Veron, Guillermo; Maltsev, Victor A.; Stern, Michael D.

Subjects: Quantitative Biology - Subcellular Processes; Physics - Biological Physics; Quantitative Biology - Molecular Networks

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Copy Number Variants in Cardiac Channelopathies: Still a Missed Part in Routine Arrhythmic Diagnostics.

• Authors : Gnazzo M; Laboratory of Medical Genetics, Translational Cytogenomics Research Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.; Parlapiano G

Subjects: DNA Copy Number Variations*/DNA Copy Number Variations*/DNA Copy Number Variations*/genetics ; Channelopathies*/Channelopathies*/Channelopathies*/genetics ; Channelopathies*/Channelopathies*/Channelopathies*/diagnosis

• Source: Biomolecules [Biomolecules] 2024 Nov 15; Vol. 14 (11). Date of Electronic Publication: 2024 Nov 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Structure-Function Relationship of the Ryanodine Receptor Cluster Network in Sinoatrial Node Cells.

• Authors : Maltsev AV; National Institute on Aging, NIH, Baltimore, MD 21224, USA.; Ventura Subirachs V

Subjects: Sinoatrial Node*/Sinoatrial Node*/Sinoatrial Node*/metabolism ; Sinoatrial Node*/Sinoatrial Node*/Sinoatrial Node*/cytology ; Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/metabolism

• Source: Cells [Cells] 2024 Nov 14; Vol. 13 (22). Date of Electronic Publication: 2024 Nov 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Using a Failing Human Ventricular Cardiomyocyte Model to Re-Evaluate Ca 2+ Cycling, Voltage Dependence, and Spark Characteristics.

• Authors : Alvarez JAE; School of Systems Biology, George Mason University, Fairfax, VA 22030, USA.; US Naval Research Laboratory, Center for Bio/Molecular Science and Engineering, Washington, DC 20375, USA.

Subjects: Myocytes, Cardiac*/Myocytes, Cardiac*/Myocytes, Cardiac*/metabolism ; Heart Failure*/Heart Failure*/Heart Failure*/metabolism ; Calcium*/Calcium*/Calcium*/metabolism

• Source: Biomolecules [Biomolecules] 2024 Oct 28; Vol. 14 (11). Date of Electronic Publication: 2024 Oct 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Compound Heterozygous RYR1 Variants in a Patient with Severe Congenital Myopathy: Case Report and Comparison with Additional Cases of Recessive RYR1 -Related Myopathy.

• Authors : Janßen S; Department of Neuropediatrics, University Children's Hospital, Ruhr-University Bochum, 44791 Bochum, Germany.; Erbe LS

Subjects: Heterozygote* ; Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/genetics; Child

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 09; Vol. 25 (19). Date of Electronic Publication: 2024 Oct 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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The Role of Ryanodine Receptor 2 Polymorphisms in Oral Squamous Cell Carcinoma Susceptibility and Clinicopathological Features.

• Authors : Hsu CH; Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, Changhua 500, Taiwan.; Institute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.

Subjects: Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/genetics ; Polymorphism, Single Nucleotide* ; Genetic Predisposition to Disease*

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Sep 25; Vol. 25 (19). Date of Electronic Publication: 2024 Sep 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Inositol trisphosphate and ryanodine receptor signaling distinctly regulate neurite pathfinding in response to engineered micropatterned surfaces.

• Authors : Vecchi JT; Department of Molecular Physiology and Biophysics, Carver College of Medicine, Iowa City, IA, United States of America.; Department of Otolaryngology Head-Neck Surgery, Carver College of Medicine, Iowa City, IA, United States of America.

Subjects: Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/metabolism ; Neurites*/Neurites*/Neurites*/metabolism ; Signal Transduction*

• Source: PloS one [PLoS One] 2024 Sep 05; Vol. 19 (9), pp. e0308389. Date of Electronic Publication: 2024 Sep 05 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Carvedilol suppresses ryanodine receptor-dependent Ca2+ bursts in human neurons bearing PSEN1 variants found in early onset Alzheimer's disease.

• Authors : Hori A; Department of Clinical Laboratory Technology, Faculty of Medical Science, Juntendo University, Chiba, Japan.; Inaba H

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology

• Source: PloS one [PLoS One] 2024 Aug 22; Vol. 19 (8), pp. e0291887. Date of Electronic Publication: 2024 Aug 22 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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