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  • 1-10 ل  87,899 نتائج ل ""Proteolysis""

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Academic Journal

Proteolysis Targeting Chimera Agents (PROTACs): New Hope for Overcoming the Resistance Mechanisms in Oncogene-Addicted Non-Small Cell Lung Cancer.

  • Authors : Cordani N; School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.; Nova D

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 18; Vol. 25 (20). Date of Electronic Publication: 2024 Oct 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

DiffPROTACs is a deep learning-based generator for proteolysis targeting chimeras.

  • Authors : Li F; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Pudong New Area, Shanghai 201210, China.; School of Information Science and Technology, ShanghaiTech University, 393 Middle Huaxia Road, Pudong New Area, Shanghai 201210, China.

Subjects: Deep Learning* ; Proteolysis*; Drug Design

  • Source: Briefings in bioinformatics [Brief Bioinform] 2024 Jul 25; Vol. 25 (5).Publisher: Oxford University Press Country of Publication: England NLM ID: 100912837 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Coordinated DNA polymerization by Polγ and the region of LonP1 regulated proteolysis.

Subjects: *MITOCHONDRIAL DNA; *DEOXYRIBOZYMES; *REPLICATION fork

  • Source: Nucleic Acids Research. 7/22/2024, Vol. 52 Issue 13, p7863-7875. 13p.

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Academic Journal

Mck1-mediated proteolysis of CENP-A prevents mislocalization of CENP-A for chromosomal stability in Saccharomyces cerevisiae.

Subjects: CENP-A; Cdc4; Cse4

  • Source: Genetics. 228(1)

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Academic Journal

The lowdown on breakdown: Open questions in plant proteolysis.

Subjects: Proteolysis; Plant Proteins; Plants

  • Source: The Plant Cell. 36(9)

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Academic Journal

Bacterial TonB-dependent transducers interact with the anti-σ factor in absence of the inducing signal protecting it from proteolysis.

  • Authors : Wettstadt S; Department of Biotechnology and Environmental Protection, Estación Experimental del Zaidín-Consejo Superior de Investigaciones Científicas, Granada, Spain.; Marcos-Torres FJ

Subjects: Proteolysis* ; Bacterial Proteins*/Bacterial Proteins*/Bacterial Proteins*/metabolism ; Bacterial Proteins*/Bacterial Proteins*/Bacterial Proteins*/genetics

  • Source: PLoS biology [PLoS Biol] 2024 Dec 02; Vol. 22 (12), pp. e3002920. Date of Electronic Publication: 2024 Dec 02 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

14-3-3 proteins inhibit autophagy by regulating SINAT-mediated proteolysis of ATG6 in Arabidopsis.

  • Authors : Liu T; Guangdong Laboratory for Lingnan Modern Agriculture, Guangdong Provincial Key Laboratory of Agricultural & Rural Pollution Abatement and Environmental Safety, College of Natural Resources and Environment, South China Agricultural University, Guangzhou, 510642, China.; Guangdong Provincial Key Laboratory of Microbial Signals and Disease Control, Integrate Microbiology Research Center, College of Plant Protection, South China Agricultural University, Guangzhou, 510642, China.

Subjects: 14-3-3 Proteins*/14-3-3 Proteins*/14-3-3 Proteins*/metabolism ; 14-3-3 Proteins*/14-3-3 Proteins*/14-3-3 Proteins*/genetics ; Arabidopsis*/Arabidopsis*/Arabidopsis*/metabolism

  • Source: BMC plant biology [BMC Plant Biol] 2024 Nov 29; Vol. 24 (1), pp. 1148. Date of Electronic Publication: 2024 Nov 29.Publisher: BioMed Central Country of Publication: England NLM ID: 100967807 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2229

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Academic Journal

LncRNA FAISL Inhibits Calpain 2-Mediated Proteolysis of FAK to Promote Progression and Metastasis of Triple Negative Breast Cancer.

  • Authors : Zhang Y; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.; Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/genetics ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/metabolism ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/pathology

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Nov; Vol. 11 (42), pp. e2407493. Date of Electronic Publication: 2024 Sep 17.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

A Crucial Role of Proteolysis in the Formation of Intracellular Dinitrosyl Iron Complexes.

Subjects: *FERRITIN; *ELECTRON paramagnetic resonance; *MOLECULES

  • Source: Molecules. Apr2024, Vol. 29 Issue 7, p1630. 17p.

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Academic Journal

Pathological mutations promote proteolysis of mitochondrial tRNA-specific 2-thiouridylase 1 (MTU1) via mitochondrial caseinolytic peptidase (CLPP).

Subjects: *PEPTIDASE; *PROTEOLYSIS; *MOLECULAR chaperones

  • Source: Nucleic Acids Research. 2/9/2024, Vol. 52 Issue 3, p1341-1358. 18p.

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  • 1-10 ل  87,899 نتائج ل ""Proteolysis""