نتائج البحث

9,10-Dioxoanthracenyldithiocarbamates effectively inhibit the proliferation of non-small cell lung cancer by targeting multiple protein tyrosine kinases.

• Authors : Olszewski M; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry, Gdansk University of Technology, Gdansk, Poland.; Stasevych M

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/metabolism ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/drug therapy

• Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2024 Dec; Vol. 39 (1), pp. 2284113. Date of Electronic Publication: 2023 Dec 11.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Preventive Effect of Pharmaceutical Phytochemicals Targeting the Src Family of Protein Tyrosine Kinases and Aryl Hydrocarbon Receptor on Environmental Stress-Induced Skin Disease.

• Authors : Paik SJ; School of Food Science and Biotechnology, Kyungpook National University, Daegu 41566, Republic of Korea.; Kim DJ

Subjects: Protein-Tyrosine Kinases* ; Skin Diseases*; Humans

• Source: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 21; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Promotion of beta cell proliferation through DYRK kinase inhibition using the marine natural product breitfussin C.

• Authors : Ullsten S; MARBIO, UiT - The Arctic University of Norway, Breivika, 9037, Tromsø, Norway.; Østnes Hansen K

Subjects: Insulin-Secreting Cells*/Insulin-Secreting Cells*/Insulin-Secreting Cells*/drug effects ; Insulin-Secreting Cells*/Insulin-Secreting Cells*/Insulin-Secreting Cells*/metabolism ; Cell Proliferation*/Cell Proliferation*/Cell Proliferation*/drug effects

• Source: Scientific reports [Sci Rep] 2025 Jan 08; Vol. 15 (1), pp. 1247. Date of Electronic Publication: 2025 Jan 08.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Differential regulatory effects of the N-terminal region in SYK-fusion kinases reveal unique activation-inducible nuclear translocation of ITK-SYK.

• Authors : Hamasy A; Department of Laboratory Medicine, Karolinska Institutet, ANA Futura, Alfred Nobels Allé 8, Floor 8, 14152, Huddinge, Sweden. .; Department of Clinical Analysis, College of Pharmacy, Hawler Medical University, Erbil, Kurdistan Region, Iraq. .

Subjects: Syk Kinase*/Syk Kinase*/Syk Kinase*/metabolism ; Syk Kinase*/Syk Kinase*/Syk Kinase*/genetics ; Protein-Tyrosine Kinases*/Protein-Tyrosine Kinases*/Protein-Tyrosine Kinases*/metabolism

• Source: Scientific reports [Sci Rep] 2025 Jan 04; Vol. 15 (1), pp. 814. Date of Electronic Publication: 2025 Jan 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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PD-1 interactome in osteosarcoma: identification of a novel PD-1/AXL interaction conserved between humans and dogs.

• Authors : Dziubek K; International Centre for Cancer Vaccine Science, University of Gdansk, Gdansk, Poland.; Faktor J

Subjects: Osteosarcoma*/Osteosarcoma*/Osteosarcoma*/metabolism ; Osteosarcoma*/Osteosarcoma*/Osteosarcoma*/pathology ; Osteosarcoma*/Osteosarcoma*/Osteosarcoma*/genetics

• Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Dec 18; Vol. 22 (1), pp. 605. Date of Electronic Publication: 2024 Dec 18.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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Multiple Tumors in a Patient with Interleukin-2-Inducible T-Cell Kinase Deficiency: A Case Report.

• Authors : Di Filippo M; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal-Infantile Sciences, University of Genoa, 16147 Genoa, Italy.; Tallone R

Subjects: Protein-Tyrosine Kinases*/Protein-Tyrosine Kinases*/Protein-Tyrosine Kinases*/genetics ; Protein-Tyrosine Kinases*/Protein-Tyrosine Kinases*/Protein-Tyrosine Kinases*/deficiency; Humans

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 07; Vol. 25 (23). Date of Electronic Publication: 2024 Dec 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation.

• Authors : Tu HJ; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.; Chao MW

Subjects: Dyrk Kinases* ; Protein-Tyrosine Kinases*/Protein-Tyrosine Kinases*/Protein-Tyrosine Kinases*/antagonists & inhibitors ; Protein-Tyrosine Kinases*/Protein-Tyrosine Kinases*/Protein-Tyrosine Kinases*/metabolism

• Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2024 Dec; Vol. 39 (1), pp. 2418470. Date of Electronic Publication: 2024 Nov 04.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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HGS Promotes Tumor Growth, Whereas the Coiled-Coil Domain and Its Oligopeptide of HGS Suppress It.

• Authors : Ogura, Kiyoshi¹ (AUTHOR) ; Kawashima, Ikuo¹ (AUTHOR); Kasahara, Kohji¹ (AUTHOR)

Subjects: *CANCER cell growth; *TUMOR growth; *PROTEIN-tyrosine kinases

• Source: International Journal of Molecular Sciences. Jan2025, Vol. 26 Issue 2, p772. 17p.

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Fasciola gigantica Recombinant Abelson Tyrosine Protein Kinase (r Fg Abl) Regulates Various Functions of Buffalo Peripheral Blood Mononuclear Cells.

• Authors : Zhao, Min¹ (AUTHOR) ; Zhou, Yu¹ (AUTHOR); Chen, Wanting¹ (AUTHOR)

• Source: Animals (2076-2615). Jan2025, Vol. 15 Issue 2, p179. 14p.

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Dual‐Action Psoriasis Therapy: Antiproliferative and Immunomodulatory Effects via Self‐Locking Microneedles.

• Authors : Wang, Zi Yi^1,2 (AUTHOR); Zhao, Ze Qiang^3,4 (AUTHOR); Sheng, Yu Jun² (AUTHOR)

• Source: Advanced Science. 12/26/2024, Vol. 11 Issue 48, p1-16. 16p.

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