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Mitochondrial protein heterogeneity stems from the stochastic nature of co-translational protein targeting in cell senescence.

• Authors : Khan, Abdul; Gu, Xuefang; Patel, Rutvik

Subjects: Cellular Senescence; Mitochondrial Proteins; Humans

• Source: Nature Communications. 15(1)

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A Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian Cancers

• Source: A Phase 1a/1b Study of 27T51, an Anti-MUC16 CAR T Cell Drug Product Administered Alone or in Combination for Participants With Recurrent or Refractory Epithelial Ovarian, Primary Peritoneal, or

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Non-enzymatic protein targeting agents as a promising strategy for cancer treatment

• Authors : Madison Ambrose; Jeremy Lee; Aleem Syed

Subjects: protein-protein interaction (PPI); proteolysis targeting chimera (PROTAC); non-enzymatic protein targeting agents

• Source: Frontiers in Drug Discovery, Vol 5 (2025)

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Envelope Protein-Targeting Zika Virus Entry Inhibitors.

• Authors : Roy, Abhijeet¹ (AUTHOR); Liu, Qian¹ (AUTHOR); Yang, Yang² (AUTHOR)

Subjects: *ZIKA virus infections; *CYTOSKELETAL proteins; *LIFE cycles (Biology)

• Source: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 17, p9424. 15p.

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Crystal structure of Kunitz-type trypsin inhibitor: Entomotoxic effect of native and encapsulated protein targeting gut trypsin of Tribolium castaneum Herbst

• Authors : Sohaib Mehmood; Soren Skou Thirup; Sarah Ahmed

Subjects: Albizia procera; Kunitz–type trypsin inhibitor; Crystal structure

• Source: Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3132-3142 (2024)

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Mitochondrial protein heterogeneity stems from the stochastic nature of co-translational protein targeting in cell senescence

• Authors : Abdul Haseeb Khan; Xuefang Gu; Rutvik J. Patel

Subjects: Science

• Source: Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)

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A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological Tumors

• Source: A Phase 1, Open-label, Multi-center, Dose Escalation Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of HCB101 in Subjects With Advanced Solid Tumors or Relapsed and

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Multi class intracellular protein targeting predictions in diatoms and other algae with complex plastids: ASAFind 2.0

• Authors : Gruber, Ansgar; McKay, Cedar; Oborník, Miroslav

Subjects: Quantitative Biology - Subcellular Processes

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Efficacy and Safety of Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting Transforming Growth Factor-β and Programmed Death-Ligand 1, Plus Chemotherapy in Patients With Stage IV NSCLC

• Authors : Christian Rolfo, MD, PhD; Laurent Greillier, MD, PhD; Remi Veillon, MD, PhD

Subjects: Bintrafusp alfa; TGF-β; Bifunctional

• Source: JTO Clinical and Research Reports, Vol 6, Iss 1, Pp 100748- (2025)

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Pre-Clinical Studies of a Novel Bispecific Fusion Protein Targeting C3b and VEGF in Neovascular and Nonexudative AMD Models.

• Authors : Lee, Yeri¹ (AUTHOR); Kim, Donggeon¹ (AUTHOR); Chung, Philip E. D.¹ (AUTHOR)

• Source: Ophthalmology & Therapy. Aug2024, Vol. 13 Issue 8, p2227-2242. 16p.

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