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  • 1-10 ل  7,500 نتائج ل ""Proteasome Endopeptidase Complex""

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Academic Journal

Identification of Malaria-Selective Proteasome β5 Inhibitors Through Pharmacophore Modeling, Molecular Docking, and Molecular Dynamics Simulation.

  • Authors : Yasir M; Department of Pharmacology, Kangwon National University School of Medicine, Chuncheon 24341, Republic of Korea.; Park J

Subjects: Molecular Dynamics Simulation* ; Molecular Docking Simulation* ; Antimalarials*/Antimalarials*/Antimalarials*/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 05; Vol. 25 (22). Date of Electronic Publication: 2024 Nov 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Emerging Role of Ubiquitin Proteasome System and Autophagy in Pediatric Demyelinating Leukodystrophies and Therapeutic Opportunity.

  • Authors : Lin DS; Department of Translational Medicine, MacKay Memorial Hospital, 92, Section 2, Chung-Shan North Road, Taipei 10449, Taiwan.; Department of Pediatrics, MacKay Memorial Hospital, Taipei 10449, Taiwan.

Subjects: Autophagy* ; Demyelinating Diseases*/Demyelinating Diseases*/Demyelinating Diseases*/metabolism ; Demyelinating Diseases*/Demyelinating Diseases*/Demyelinating Diseases*/pathology

  • Source: Cells [Cells] 2024 Nov 12; Vol. 13 (22). Date of Electronic Publication: 2024 Nov 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Targeting Immunoproteasome in Polarized Macrophages Ameliorates Experimental Emphysema Via Activating NRF1/2-P62 Axis and Suppressing IRF4 Transcription.

  • Authors : Guo B; Department of Pulmonary and Critical Care Medicine, Shenzhen Institute of Respiratory Diseases, The First Affiliated Hospital (Shenzhen People's Hospital) and School of Medicine, Southern University of Science and Technology, Shenzhen, 518055, China.; Shi X

Subjects: NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/metabolism ; NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/genetics ; Macrophages*/Macrophages*/Macrophages*/metabolism

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Nov; Vol. 11 (44), pp. e2405318. Date of Electronic Publication: 2024 Oct 02.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

Functional 20S Proteasomes in Retroviruses: Evidence in Favor.

  • Authors : Morozov V; Department of Infectious Diseases, Robert Koch Institute, 13353 Berlin, Germany.; Morozov A

Subjects: Proteasome Endopeptidase Complex*/Proteasome Endopeptidase Complex*/Proteasome Endopeptidase Complex*/metabolism ; Retroviridae*/Retroviridae*/Retroviridae*/physiology ; Retroviridae*/Retroviridae*/Retroviridae*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 31; Vol. 25 (21). Date of Electronic Publication: 2024 Oct 31.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

The Structural Role of RPN10 in the 26S Proteasome and an RPN2-Binding Residue on RPN13 Are Functionally Important in Arabidopsis.

  • Authors : Lin SY; Institute of Plant and Microbial Biology, Academia Sinica, Taipei 115, Taiwan.; Lin YL

Subjects: Proteasome Endopeptidase Complex*/Proteasome Endopeptidase Complex*/Proteasome Endopeptidase Complex*/metabolism ; Arabidopsis*/Arabidopsis*/Arabidopsis*/genetics ; Arabidopsis*/Arabidopsis*/Arabidopsis*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 30; Vol. 25 (21). Date of Electronic Publication: 2024 Oct 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

CHIP drives proteasomal degradation of NUR77 to alleviate oxidative stress and intrinsic apoptosis in cisplatin-induced nephropathy.

  • Authors : Zhang H; Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, Tianjin, 300211, China.; Deng Z

Subjects: Cisplatin*/Cisplatin*/Cisplatin*/toxicity ; Cisplatin*/Cisplatin*/Cisplatin*/adverse effects ; Cisplatin*/Cisplatin*/Cisplatin*/pharmacology

  • Source: Communications biology [Commun Biol] 2024 Oct 26; Vol. 7 (1), pp. 1403. Date of Electronic Publication: 2024 Oct 26.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

NDRG1 upregulation by ubiquitin proteasome system dysfunction aggravates neurodegeneration.

  • Authors : Hoshino T; Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, 606-8503, Japan.; Neuroprotection Research Laboratories, Departments of Radiology and Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.

Subjects: Up-Regulation*/Up-Regulation*/Up-Regulation*/genetics ; Cell Cycle Proteins*/Cell Cycle Proteins*/Cell Cycle Proteins*/metabolism ; Cell Cycle Proteins*/Cell Cycle Proteins*/Cell Cycle Proteins*/genetics

  • Source: Molecular brain [Mol Brain] 2024 Oct 23; Vol. 17 (1), pp. 77. Date of Electronic Publication: 2024 Oct 23.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606

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Academic Journal

miR-326 overexpression inhibits colorectal cancer cell growth and proteasome activity by targeting PNO1: unveiling a novel therapeutic intervention strategy.

  • Authors : Fang Y; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350108, Fujian, China.; Fujian Key Laboratory of Integrative Medicine in Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, 350108, Fujian, China.

Subjects: Proteasome Endopeptidase Complex*/Proteasome Endopeptidase Complex*/Proteasome Endopeptidase Complex*/metabolism ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/genetics ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/pathology

  • Source: Scientific reports [Sci Rep] 2024 Oct 16; Vol. 14 (1), pp. 24284. Date of Electronic Publication: 2024 Oct 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

ProEnd: a comprehensive database for identifying HbYX motif-containing proteins across the tree of life.

  • Authors : Salcedo-Tacuma D; Department of Biochemistry and Molecular Medicine, West Virginia University School of Medicine, 4 Medical Center Dr, Morgantown, WV, USA.; Howells GD

Subjects: Databases, Protein* ; Proteasome Endopeptidase Complex*/Proteasome Endopeptidase Complex*/Proteasome Endopeptidase Complex*/metabolism ; Amino Acid Motifs*

  • Source: BMC genomics [BMC Genomics] 2024 Oct 13; Vol. 25 (1), pp. 951. Date of Electronic Publication: 2024 Oct 13.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164

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Academic Journal

Investigating the p21 Ubiquitin-Independent Degron Reveals a Dual Degron Module Regulating p21 Degradation and Function.

  • Authors : Riutin M; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot P.O. Box 26, Israel.; Erez P

Subjects: Cyclin-Dependent Kinase Inhibitor p21*/Cyclin-Dependent Kinase Inhibitor p21*/Cyclin-Dependent Kinase Inhibitor p21*/metabolism ; Cyclin-Dependent Kinase Inhibitor p21*/Cyclin-Dependent Kinase Inhibitor p21*/Cyclin-Dependent Kinase Inhibitor p21*/genetics ; Proteolysis*

  • Source: Cells [Cells] 2024 Oct 09; Vol. 13 (19). Date of Electronic Publication: 2024 Oct 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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  • 1-10 ل  7,500 نتائج ل ""Proteasome Endopeptidase Complex""