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Poly (ADP-Ribose) Polymerase Inhibitor Olaparib-Resistant BRCA1 -Mutant Ovarian Cancer Cells Demonstrate Differential Sensitivity to PARP Inhibitor Rechallenge.

• Authors : Shih CT; Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD 20892, USA.; Huang TT

Subjects: Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/drug therapy ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/genetics

• Source: Cells [Cells] 2024 Nov 07; Vol. 13 (22). Date of Electronic Publication: 2024 Nov 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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[ 18 F]F-Poly(ADP-Ribose) Polymerase Inhibitor Radiotracers for Imaging PARP Expression and Their Potential Clinical Applications in Oncology.

• Authors : Ndlovu, Honest^1,2 (AUTHOR) ; Lawal, Ismaheel O.^2,3 (AUTHOR); Mdanda, Sipho^1,2 (AUTHOR)

• Source: Journal of Clinical Medicine. Jun2024, Vol. 13 Issue 12, p3426. 15p.

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Nanoparticles-SIRT1 Prevents Endothelial Progenitor Cells Senescence by Modulating Nitric Oxide Expression and Reducing Poly ADP-ribose Polymerase: In vitro Study.

• Authors : Wihastuti, Titin Andri¹; Chomsy, Indah Nur²; Nurwidyaningtyas, Wiwit²

• Source: Trends in Sciences. Jun2024, Vol. 21 Issue 6, p1-9. 9p.

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Poly(ADP-Ribose) Polymerase (PARP) Inhibitors for Cancer Therapy: Advances, Challenges, and Future Directions.

• Authors : Bondar D; Department of Chemistry and Biotechnology, Tallinn University of Technology (TalTech), Akadeemia tee 15, 12618 Tallinn, Estonia.; Karpichev Y

Subjects: Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/therapeutic use ; Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology ; Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/chemistry

• Source: Biomolecules [Biomolecules] 2024 Oct 09; Vol. 14 (10). Date of Electronic Publication: 2024 Oct 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Clinical Outcomes of Poly(ADP-Ribose) Polymerase Inhibitors as Maintenance Therapy in Patients with Ovarian Cancer in the Southeastern Region of Korea.

• Authors : Ha HI; Department of Obstetrics and Gynecology, Pusan National University College of Medicine, Busan 49241, Republic of Korea.; Department of Obstetrics and Gynecology, Pusan National University Yangsan Hospital, Yangsan-si 50612, Republic of Korea.

Subjects: Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/therapeutic use ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/drug therapy; Humans

• Source: Current oncology (Toronto, Ont.) [Curr Oncol] 2024 Oct 28; Vol. 31 (11), pp. 6711-6722. Date of Electronic Publication: 2024 Oct 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 9502503 Publication Model: Electronic Cited Medium: Internet ISSN: 1718-7729

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Synergistic Cytotoxicity of Histone Deacetylase and Poly-ADP Ribose Polymerase Inhibitors and Decitabine in Breast and Ovarian Cancer Cells: Implications for Novel Therapeutic Combinations.

• Authors : Valdez BC; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.; Tsimberidou AM

Subjects: Decitabine*/Decitabine*/Decitabine*/pharmacology ; Drug Synergism* ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 26; Vol. 25 (17). Date of Electronic Publication: 2024 Aug 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Comparative analysis of the primary structure and production of recombinant poly(ADP-ribose)polymerase 1 of long-lived Heterocephalus glaber

• Authors : K. N. Naumenko; A. R. Nurislamov; K. D. Nazarov

Subjects: poly(adp-ribose)polymerase 1; dna repair; heterocephalus glaber

• Source: Вавиловский журнал генетики и селекции, Vol 28, Iss 7, Pp 688-695 (2024)

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Proteomic landscaping of high-grade serous ovarian carcinoma identifies stearoyl-CoA desaturase 5 as a potential predictive biomarker for poly(ADP-ribose) polymerase inhibitor response.

• Authors : Kim SI; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Republic of Korea.

Subjects: Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/drug therapy ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/metabolism ; Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/therapeutic use

• Source: Clinical and translational medicine [Clin Transl Med] 2024 May; Vol. 14 (5), pp. e1693.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet ISSN: 2001-1326

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Colon-Targeted Poly(ADP-ribose) Polymerase Inhibitors Synergize Therapeutic Effects of Mesalazine Against Rat Colitis Induced by 2,4-Dinitrobenzenesulfonic Acid.

• Authors : Kang, Changyu¹ (AUTHOR) ; Kim, Jaejeong¹ (AUTHOR); Jeong, Yeonhee¹ (AUTHOR)

• Source: Pharmaceutics. Dec2024, Vol. 16 Issue 12, p1546. 17p.

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Targeted Combination of Poly(ADP-ribose) Polymerase Inhibitors and Immune Checkpoint Inhibitors Lacking Evidence of Benefit: Focus in Ovarian Cancer.

• Authors : Bailey M; Department of Medicine, University of Toledo, Toledo, OH 43614, USA.; Morand S

Subjects: Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/therapeutic use ; Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/drug therapy

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 09; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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