نتائج البحث

The phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, PAICS, is differentially expressed following infection by the coronavirus family

• Authors : Shahan Mamoor

Subjects: viruses; virus diseases

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Mapping of a locus correcting lack of phosphoribosylaminoimidazole carboxylase activity in Chinese hamster ovary cell Ade−D mutants to human chromosome 4

• Authors : David Patterson; Iris Hart; Jeffrey W. Barton

Subjects: Genetics; Phosphoribosylaminoimidazole carboxylase activity; Phosphoribosylaminoimidazole carboxylase

• Source: Genomics. 9:314-321

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The gene encoding phosphoribosylaminoimidazole carboxylase (ADE2) is essential for growth of Cryptococcus neoformans in cerebrospinal fluid

• Authors : Dena L. Toffaletti; Thomas H. Rude; John R. Perfect

Subjects: Male; Carboxy-Lyases; Auxotrophy

• Source: Infection and Immunity. 61:4446-4451

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Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target

• Authors : Škerlová, Jana; Unterlass, Judith; Göttmann, Mona

Subjects: de novo purine biosynthesis; nucleotide metabolism; cancer target

• Source: Journal of Biological Chemistry. 295(33):11656-11668

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Purification and properties of an enzyme duet, phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthetase, involved in the biosynthesis of purine nucleotides de novo (Short Communication)

• Authors : Gordon Shaw; Carole Anne Hilton Patey

Subjects: Purine; Carboxy-Lyases; Phosphoribosylaminoimidazolesuccinocarboxamide

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In vivo deep network tracing reveals phosphofructokinase-mediated coordination of biosynthetic pathway activity in the myocardium

• Authors : Timothy D. Cummins; Teresa Cassel; William L. Dean

Subjects: Phosphofructokinase-2; Phosphofructokinase-1; Article

• Source: Journal of molecular and cellular cardiology

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PAICS contributes to gastric carcinogenesis and participates in DNA damage response by interacting with histone deacetylase 1/2

• Authors : Shuping Long; Xue Li; Chang Xu

Subjects: Male; Cancer Research; DNA Repair

• Source: Cell Death & DiseaseCell Death and Disease, Vol 11, Iss 7, Pp 1-13 (2020)

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The CRISPR-Cas9 crATIC HeLa transcriptome: Characterization of a novel cellular model of ATIC deficiency and ZMP accumulation

• Authors : Randall C. Mazzarino; David Patterson; Terry G. Wilkinson

Subjects: AMP-activated protein kinase, (AMPK); 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase, (ATIC); Ribonucleotide

• Source: Molecular Genetics and Metabolism Reports, Vol 25, Iss, Pp 100642-(2020)Molecular Genetics and Metabolism Reports

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Proteína multifuncional ADE2 como nexo entre vías de recuperación y síntesis de novo de nucleótidos

• Authors : Caviedes Cárdenas, Liska Rayen; University/Department: Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular; ...

Subjects: Nucleòtids; Nucleótidos; Nucleotides

• Source: TDX (Tesis Doctorals en Xarxa)

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A new type of gene-disruption cassette with a rescue gene for Pichia pastoris.

• Authors : Shibui, Tatsuro¹ ; Hara, Hiroyoshi¹

Subjects: *PICHIA pastoris; *GENE expression; *DNA analysis

• Source: Biotechnology Progress. Sep/Oct2017, Vol. 33 Issue 5, p1201-1208. 8p.

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