نتائج البحث

The potential radiosensitization target PFKFB3 is related to response to radiotherapy in SweBCG91RT: a randomized clinical trial with long-term follow-up.

• Authors : Egelberg M; Division of Surgery, Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, BMC D13, Lund, 221 83, Sweden. .; Division of Oncology and Pathology, Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, Lund, Sweden. .

Subjects: Phosphofructokinase-2*/Phosphofructokinase-2*/Phosphofructokinase-2*/genetics ; Phosphofructokinase-2*/Phosphofructokinase-2*/Phosphofructokinase-2*/metabolism ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/radiotherapy

• Source: BMC cancer [BMC Cancer] 2025 Feb 28; Vol. 25 (1), pp. 374. Date of Electronic Publication: 2025 Feb 28.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Repression of PFKFB3 sensitizes ovarian cancer to PARP inhibitors by impairing homologous recombination repair.

• Authors : Xiao Y; Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China.; National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital), Beijing, 100191, China.

Subjects: Phosphofructokinase-2*/Phosphofructokinase-2*/Phosphofructokinase-2*/genetics ; Phosphofructokinase-2*/Phosphofructokinase-2*/Phosphofructokinase-2*/metabolism ; Phosphofructokinase-2*/Phosphofructokinase-2*/Phosphofructokinase-2*/antagonists & inhibitors

• Source: Cell communication and signaling : CCS [Cell Commun Signal] 2025 Jan 25; Vol. 23 (1), pp. 48. Date of Electronic Publication: 2025 Jan 25.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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Micheliolide attenuates sepsis-induced acute lung injury by suppressing mitochondrial oxidative stress and PFKFB3-driven glycolysis.

• Authors : Li W; Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, 1838 Guangzhou North Road, Guangzhou, 510515, China.; Li Y

Subjects: Glycolysis*/Glycolysis*/Glycolysis*/drug effects ; Sepsis*/Sepsis*/Sepsis*/complications ; Sepsis*/Sepsis*/Sepsis*/drug therapy

• Source: Journal of translational medicine [J Transl Med] 2025 Feb 14; Vol. 23 (1), pp. 181. Date of Electronic Publication: 2025 Feb 14.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Single-Cell RNA-Seq Analysis Links DNMT3B and PFKFB4 Transcriptional Profiles with Metastatic Traits in Hepatoblastoma.

• Authors : Desterke C; Faculté de Médecine du Kremlin Bicêtre, Université Paris-Sud, Université Paris-Saclay, 94270 Le Kremlin-Bicêtre, France.; Francés R

Subjects: Hepatoblastoma*/Hepatoblastoma*/Hepatoblastoma*/genetics ; Hepatoblastoma*/Hepatoblastoma*/Hepatoblastoma*/pathology ; Hepatoblastoma*/Hepatoblastoma*/Hepatoblastoma*/metabolism

• Source: Biomolecules [Biomolecules] 2024 Oct 31; Vol. 14 (11). Date of Electronic Publication: 2024 Oct 31.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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The Folding Unit of Phosphofructokinase-2 as Defined by the Biophysical Properties of a Monomeric Mutant

• Authors : Ramírez-Sarmiento, César A; Baez, Mauricio; Zamora, Ricardo A

Subjects: Biochemistry and Cell Biology; Chemical Sciences; Biological Sciences

• Source: Biophysical Journal. 108(9)

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PFKFB3 downregulation aggravates Angiotensin II-induced podocyte detachment.

• Authors : Huang X; Division of Nephrology, Renmin Hospital of Wuhan University, Wuhan, China.; Chen Z

Subjects: Podocytes*/Podocytes*/Podocytes*/metabolism ; Renal Insufficiency, Chronic*/Renal Insufficiency, Chronic*/Renal Insufficiency, Chronic*/metabolism ; Phosphofructokinase-2*/Phosphofructokinase-2*/Phosphofructokinase-2*/genetics

• Source: Renal failure [Ren Fail] 2023 Dec; Vol. 45 (1), pp. 2230318.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print Cited Medium: Internet ISSN: 1525-6049

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Expression of Pfkfb isoenzymes during in vitro differentiation of mouse embryonic stem cells into insulin-producing cells.

• Authors : Güzel S; Department of Biochemistry, Faculty of Veterinary Medicine, Bursa Uludağ University, Bursa, Turkiye.; Yalçin A

Subjects: Cell Differentiation* ; Isoenzymes*/Isoenzymes*/Isoenzymes*/metabolism ; Isoenzymes*/Isoenzymes*/Isoenzymes*/genetics

• Source: Turkish journal of medical sciences [Turk J Med Sci] 2023 Aug 11; Vol. 53 (6), pp. 1565-1573. Date of Electronic Publication: 2023 Aug 11 (Print Publication: 2023).Publisher: Scientific and Technical Research Council of Turkey Country of Publication: Turkey NLM ID: 9441758 Publication Model: eCollection Cited Medium:

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Dysfunctional β-cell longevity in diabetes relies on energy conservation and positive epistasis.

• Authors : Raval, Kavit; Jamshidi, Neema; Seyran, Berfin

Subjects: Insulin-Secreting Cells; Animals; Diabetes Mellitus

• Source: Life Science Alliance. 7(12)

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A Comprehensive Model For The Mechanism Of Allosteric Regulation Of E. Coli Phosphofructokinase-2. Integration Of Kinetic, Structural, Dynamic And Mechanic Aspects.

• Authors : Cattan, Jorge Babul; Universidad De Chile

Subjects: Biologia 3; Ciencias Naturales

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KLF4-PFKFB3-driven glycolysis is essential for phenotypic switching of vascular smooth muscle cells.

• Authors : Zhang X; Department of Biochemistry and Molecular Biology, the Key Laboratory of Neural and Vascular Biology, Ministry of Education of China, Hebei Medical University, Shijiazhuang, China. .; Zheng B

Subjects: Atherosclerosis*/Atherosclerosis*/Atherosclerosis*/metabolism ; Muscle, Smooth, Vascular*/Muscle, Smooth, Vascular*/Muscle, Smooth, Vascular*/metabolism ; Phosphofructokinase-2*/Phosphofructokinase-2*/Phosphofructokinase-2*/metabolism

• Source: Communications biology [Commun Biol] 2022 Dec 05; Vol. 5 (1), pp. 1332. Date of Electronic Publication: 2022 Dec 05.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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