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CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials

• Authors : Neil H. Segal; Ignacio Melero; Victor Moreno

Subjects: Science

• Source: Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)

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Corrigendum to 'Results from three phase 1 trials of NNC9204-1177, a glucagon/GLP-1 receptor co-agonist: effects on weight loss and safety in adults with overweight or obesity' [Mol Metab 78 (2023) 101801]

• Authors : Martin Haljeta Friedrichsen; Lars Endahl; Frederik Flindt Kreiner

Subjects: Internal medicine; RC31-1245

• Source: Molecular Metabolism, Vol 89, Iss , Pp 102023- (2024)

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Phase 1 Trials of Gatralimab, a Next-Generation Humanized Anti-CD52 Monoclonal Antibody, in Participants with Progressive Multiple Sclerosis.

• Authors : Albach FN; Charité Research Organisation GmbH, Berlin, Germany.; Geier C

• Source: Neurology and therapy [Neurol Ther] 2024 Sep 09. Date of Electronic Publication: 2024 Sep 09.Publisher: Springer Country of Publication: New Zealand NLM ID: 101637818 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2193-8253

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Results from three phase 1 trials of NNC9204-1177, a glucagon/GLP-1 receptor co-agonist: Effects on weight loss and safety in adults with overweight or obesity

• Authors : Martin Haljeta Friedrichsen; Lars Endahl; Frederik Flindt Kreiner

Subjects: Glucagon-like peptide-1; Glucose-dependent insulinotropic polypeptide; Obesity

• Source: Molecular Metabolism, Vol 78, Iss , Pp 101801- (2023)

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P1125: DURABLES RESPONSES ACHIEVED WITH ANTI-CD19 ALLOGENEIC CAR T ALLO-501/501A IN PHASE 1 TRIALS OF AUTOLOGOUS CAR T-NAÏVE PATIENTS WITH RELAPSED/REFRACTORY LARGE B-CELL LYMPHOMA (R/R LBCL)

• Authors : Javier Munoz; Frederick Locke; Lazaros Lekakis

Subjects: Diseases of the blood and blood-forming organs; RC633-647.5

• Source: HemaSphere, Vol 7, p e8808264 (2023)

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OS09.6 Long-term follow-up data from 126 patients with recurrent high grade glioma from three Phase 1 trials of Toca 511 and Toca FC: Update and justification for a Phase 2/3 trial

• Authors : Aghi, M; Vogelbaum, MA; Kalkanis, SN

Subjects: Neurosciences; Oncology and Carcinogenesis; Oncology & Carcinogenesis

• Source: Neuro-Oncology. 19(suppl_3)

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Safety and immunogenicity of two recombinant DNA COVID-19 vaccines containing the coding regions of the spike or spike and nucleocapsid proteins: an interim analysis of two open-label, non-randomised, phase 1 trials in healthy adults

• Authors : Jin Young Ahn, MD; Jeongsoo Lee, MD; You Suk Suh, PhD

Subjects: Medicine (General); R5-920; Microbiology

• Source: The Lancet Microbe, Vol 3, Iss 3, Pp e173-e183 (2022)

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Clinical development success rates and social value of pediatric Phase 1 trials in oncology.

• Authors : Wasylewski, Mateusz T.¹ (AUTHOR); Strzebonska, Karolina¹ (AUTHOR); Koperny, Magdalena¹ (AUTHOR)

Subjects: *SOCIAL values; *MEDICAL databases; *TUMORS in children

• Source: PLoS ONE. 6/24/2020, Vol. 15 Issue 6, p1-12. 12p.

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Four phase 1 trials to evaluate the safety and pharmacokinetic profile of single and repeated dosing of SCO-101 in adult male and female volunteers

• Authors : Bergmann, Troels K.; Stage, Tore B.; Stenvang, Jan

Subjects: cancer chemotherapy; development; discovery and development

• Source: Bergmann , T K , Stage , T B , Stenvang , J , Christophersen , P , Jacobsen , T A , Roest , N L , Vestlev , P M & Brunner , N 2020 , ' Four phase

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CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials

• Authors : Segal, Neil H.; MELERO BERMEJO, IGNACIO; Moreno, Victor ...

Subjects: Anticossos monoclonals - Ús terapèutic; Càncer - Immunoteràpia; Avaluació de resultats (Assistència sanitària)

• Source: Scientia

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