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evoke and evoke+:design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomatic Alzheimer's disease

• Authors : Cummings, Jeffrey L; Atri, Alireza; Feldman, Howard H

Subjects: Humans; Glucagon-Like Peptides/therapeutic use; Alzheimer Disease/drug therapy

• Source: Cummings , J L , Atri , A , Feldman , H H , Hansson , O , Sano , M , Knop , F K , Johannsen , P , León , T & Scheltens , P 2025 , ' evoke and evoke+ : design of two large-scale, double-blind,

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Implantable Technologies : Peptides and Small Molecules Drug Delivery

• Authors : Ved Srivastava

Subjects: Peptides--Therapeutic use; Drug delivery devicesSCIENCE / Chemistry / Industrial & Technical; SCIENCE / Chemistry / Clinical; SCIENCE / Chemistry / Organic

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Long-term weight loss effects of semaglutide in obesity without diabetes in the SELECT trial

• Authors : Ryan, Donna H; Lingvay, Ildiko; Deanfield, John

Subjects: Humans; Glucagon-Like Peptides/therapeutic use; Weight Loss/drug effects

• Source: Ryan , D H , Lingvay , I , Deanfield , J , Kahn , S E , Barros , E , Burguera , B , Colhoun , H M , Cercato , C , Dicker , D , Horn , D B , Hovingh , G K , Jeppesen , O K , Kokkinos , A , Lincoff , A

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Semaglutide and cardiovascular outcomes in patients with obesity and prevalent heart failure:a prespecified analysis of the SELECT trial

• Authors : Deanfield, John; Verma, Subodh; Scirica, Benjamin M

Subjects: Humans; Glucagon-Like Peptides/therapeutic use; Heart Failure/mortality

• Source: SELECT Trial Investigators , Deanfield , J , Verma , S , Scirica , B M , Kahn , S E , Emerson , S S , Ryan , D , Lingvay , I , Colhoun , H M , Plutzky , J , Kosiborod , M N , Hovingh , G K ,

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Unravelling the Gastroprotective Potential of Kefir: Exploring Antioxidant Effects in Preventing Gastric Ulcers.

• Authors : Côco, Larissa Zambom; Aires, Rafaela; Carvalho, Glaucimeire Rocha

Subjects: anti-inflammatory; bioprospection; gastroprotection

• Source: Cells, 12 (24), 2799 (2023-12-08)

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A novel D-amino acid peptide with therapeutic potential (ISAD1) inhibits aggregation of neurotoxic disease-relevant mutant Tau and prevents Tau toxicity in vitro.

• Authors : Aillaud, Isabelle; Kaniyappan, Senthilvelrajan; Funke, Susanne Aileen

Subjects: info:eu-repo/classification/ddc/610; Aged; Alzheimer Disease: drug therapyDE

• Source: Alzheimer's research & therapy 14(1), 15 (2022). doi:10.1186/s13195-022-00959-z

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A review emphasizing on utility of heptad repeat sequence as a tool to design pharmacologically safe peptide-based antibiotics.

• Authors : Vikas, Yadav; Misra, Richa

Subjects: Antimicrobial peptides; Cytotoxicity; Haematotoxicity

• Source: Biochimie, 191, 126-139 (2021-12)

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Real-world use of once-weekly semaglutide in patients with type 2 diabetes:Results from the SURE Denmark/Sweden multicentre, prospective, observational study

• Authors : Rajamand Ekberg, Neda; Bodholdt, Ulrik; Catarig, Andrei Mircea

Subjects: Body weight; Glucagon-like peptide-1 receptor agonist; HbA

• Source: Rajamand Ekberg , N , Bodholdt , U , Catarig , A M , Catrina , S B , Grau , K , Holmberg , C N , Klanger , B & Knudsen , S T 2021 , ' Real-world use of once-weekly

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Introduction of Non-natural Amino Acids Into T-Cell Epitopes to Mitigate Peptide-Specific T-Cell Responses.

• Authors : Azam, Aurélien; Mallart, Sergio; Illiano, Stephane

Subjects: CD4 T-cell response; HLA class II molecules; T-cell epitope

• Source: Frontiers in Immunology, 12, 637963 (2021)

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Delivery Of Protein And Peptide Drugs In Cancer

• Authors : Vladimir P Torchilin

Subjects: Proteins--Therapeutic use--Administration; Peptides--Therapeutic use--Administration; Drugs--Dosage formsMEDICAL / Pharmacology

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