نتائج البحث

Gene network based analysis identifies a coexpression module involved in regulating plasma lipids with high-fat diet response.

• Authors : Xu, Fuyi; Ziebarth, Jesse D; Goeminne, Ludger Je

Subjects: BXD recombinant inbred mice; Bayesian network; Mendelian randomization

• Source: Journal of Nutritional Biochemistry, 119, 109398 (2023-09)

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Genetically proxied glucose-lowering drug target perturbation and risk of cancer:a Mendelian randomisation analysis

Subjects: ABCC8; Breast cancer; Colorectal cancer

• Source: The PRACTICAL Consortium 2023 , ' Genetically proxied glucose-lowering drug target perturbation and risk of cancer : a Mendelian randomisation analysis ' , Diabetologia , vol. 66 , no. 8 , pp.

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Single-cell transcriptomics reveal cellular diversity of aortic valve and the immunomodulation by PPARγ during hyperlipidemia

• Authors : Seung Hyun Lee; Nayoung Kim; Minkyu Kim

Subjects: Animals; Aortic Valve / metabolism; Aortic Valve Stenosis

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PPARγ lipodystrophy mutants reveal intermolecular interactions required for enhancer activation

• Authors : Madsen, Maria Stahl; Broekema, Marjoleine F.; Madsen, Martin Rønn ...

Subjects: Humans; PPAR gamma/genetics; Adipocytes/metabolism

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Genome and transcriptome profiling of spontaneous preterm birth phenotypes

• Authors : Gupta, Juhi; Care, Angharad; Goodfellow, Laura

Subjects: Adult; Biomarkers/blood; Female

• Source: Gupta , J , Care , A , Goodfellow , L , Alfirevic , Z , Müller-Myhsok , B & Alfirevic , A 2022 , ' Genome and transcriptome profiling of spontaneous preterm birth phenotypes ' , Scientific Reports ,

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TRIB3 Modulates PPARγ-Mediated Growth Inhibition by Interfering with the MLL Complex in Breast Cancer Cells

• Authors : Hernández-Quiles, Miguel; Baak, Rosalie; Orea-Soufi, Alba ...

Subjects: Breast Neoplasms/genetics; Cell Cycle Proteins/metabolism; Female

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PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions.

• Authors : Ercolano, G.; Gomez-Cadena, A.; Dumauthioz, N.

Subjects: Animals; Asthma; Cytokines/pharmacology

• Source: Nature communications, vol. 12, no. 1, pp. 2538

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The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ.

• Authors : Wang, Xia; Ji, Yuge; Feng, Panpan

Subjects: IGF2BP2; TSC1; inflammatory diseases

• Source: Advanced Science, 8 (13), 2100209 (2021)

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Peroxisome proliferator-activated receptor gamma as a theragnostic target for mesenchymal-type glioblastoma patients

• Authors : Tuyen N M Hua; Jiwoong Oh; Sohyun Kim

Subjects: Animals; Antineoplastic Agents / pharmacology; Biomarkers

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Systemic PPARγ deletion in mice provokes lipoatrophy, organomegaly, severe type 2 diabetes and metabolic inflexibility.

• Authors : Winkler, C.; Quignodon, L.; Diserens, J.G.

Subjects: Adipose Tissue/anatomy & histology; Animals; Diabetes Mellitus

• Source: Metabolism, vol. 95, pp. 8-20

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