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Deep mutational scanning quantifies DNA binding and predicts clinical outcomes of PAX6 variants.

• Authors : McDonnell AF; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.; Plech M

Subjects: PAX6 Transcription Factor*/PAX6 Transcription Factor*/PAX6 Transcription Factor*/genetics ; PAX6 Transcription Factor*/PAX6 Transcription Factor*/PAX6 Transcription Factor*/metabolism ; DNA*/DNA*/DNA*/genetics

• Source: Molecular systems biology [Mol Syst Biol] 2024 Jul; Vol. 20 (7), pp. 825-844. Date of Electronic Publication: 2024 Jun 07.Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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PAX6 promotes neuroendocrine phenotypes of prostate cancer via enhancing MET/STAT5A-mediated chromatin accessibility.

• Authors : Jing N; State Key Laboratory of Systems Medicine for Cancer, Renji-Med-X Stem Cell Research Center, Ren Ji Hospital, School of Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200127, China.; Med-X Research Institutes, Shanghai Jiao Tong University, Shanghai, 200030, China.

Subjects: Chromatin*/Chromatin*/Chromatin*/metabolism ; Chromatin*/Chromatin*/Chromatin*/genetics ; PAX6 Transcription Factor*/PAX6 Transcription Factor*/PAX6 Transcription Factor*/metabolism

• Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 May 15; Vol. 43 (1), pp. 144. Date of Electronic Publication: 2024 May 15.Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966

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Pax6 基因表达对过氧化氢诱导骨髓间充质干细胞衰老的影响.

• Authors : 高 杰^1,2,3; 邹星星¹; 文邦红¹

• Source: Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu. 11/8/2024, Vol. 28 Issue 31, p4921-4925. 5p.

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PAX6 promotes neuroendocrine phenotypes of prostate cancer via enhancing MET/STAT5A-mediated chromatin accessibility

• Authors : Nan Jing; Xinxing Du; Yu Liang

Subjects: PAX6; Neuroendocrine prostate cancer; Lineage plasticity

• Source: Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-22 (2024)

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Outcome of illuminated microcatheter-assisted circumferential trabeculotomy following failed angle surgery in PAX6 aniridic glaucoma: a case report and literature review

• Authors : Tingyi Wu; Cui Cui; Yuanting Li

Subjects: Aniridia; PAX6; Aniridic glaucoma

• Source: BMC Ophthalmology, Vol 24, Iss 1, Pp 1-8 (2024)

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Puerarin attenuates remifentanil‑induced postoperative hyperalgesia via targeting PAX6 to regulate the transcription of TRPV1.

• Authors : Yuan L; Department of Anesthesiology, The General Hospital of Western Theater Command PLA, Chengdu, Sichuan 610083, P.R. China.; Liu Y

Subjects: Hyperalgesia*/Hyperalgesia*/Hyperalgesia*/chemically induced ; Hyperalgesia*/Hyperalgesia*/Hyperalgesia*/drug therapy ; Hyperalgesia*/Hyperalgesia*/Hyperalgesia*/genetics

• Source: Molecular medicine reports [Mol Med Rep] 2024 May; Vol. 29 (5). Date of Electronic Publication: 2024 Mar 22.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Whole-genome sequencing of multiple related individuals with type 2 diabetes reveals an atypical likely pathogenic mutation in the PAX6 gene

• Authors : Boehm, Bernhard O; Kratzer, Wolfgang; Bansal, Vikas

Subjects: Biological Sciences; Biomedical and Clinical Sciences; Genetics

• Source: European Journal of Human Genetics. 31(1)

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A rare missense PAX6 mutation causes atypical aniridia in a three-generation Chinese family

• Authors : Zhi-Bo Lin; Chun-Yun Feng; Jin Li

Subjects: pax6 gene; atypical aniridia; missense mutation

• Source: International Journal of Ophthalmology, Vol 17, Iss 3, Pp 466-472 (2024)

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Variants in PAX6, PITX3 and HSF4 causing autosomal dominant congenital cataracts

• Authors : Berry, Vanita; Ionides, Alex; Pontikos, Nikolas

Subjects: Genetics; Congenital Structural Anomalies; Pediatric

• Source: Eye. 36(8)

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Co-Occurrence of Congenital Aniridia Due to Nonsense PAX6 Variant p.(Cys94*) and Chromosome 21 Trisomy in the Same Patient.

• Authors : Vasilyeva, Tatyana A.¹ (AUTHOR) ; Sukhanova, Natella V.¹ (AUTHOR); Marakhonov, Andrey V.¹ (AUTHOR)

Subjects: *DOWN syndrome; *CHROMOSOMES; *TRISOMY

• Source: International Journal of Molecular Sciences. Nov2023, Vol. 24 Issue 21, p15527. 11p.

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