نتائج البحث

New isoxazolidinyl-based N-alkylethanolamines as new activators of human brain carbonic anhydrases.

• Authors : Cuffaro, Doretta¹ (AUTHOR); Di Leo, Riccardo¹ (AUTHOR); Ciccone, Lidia¹ (AUTHOR)

Subjects: *BIOTRANSFORMATION (Metabolism); *AMINO alcohols; *BRAIN research

• Source: Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2023, Vol. 38 Issue 1, p1-9. 9p.

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Identification of histone deacetylase inhibitors with (arylidene)aminoxy scaffold active in uveal melanoma cell lines

• Authors : Nencetti, Susanna; Cuffaro, Doretta; Nuti, Elisa

Subjects: Uveal melanoma; HDAC inhibitors; HDAC6

• Source: Journal of enzyme inhibition and medicinal chemistry (Print). 36(1):34-47

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Bacterial Zinc Metalloenzyme Inhibitors: Recent Advances and Future Perspectives

• Authors : Di Leo, Riccardo; Cuffaro, Doretta; Rossello, Armando ...

Subjects: Gram-negative bacteria; LpxC; antivirulence agent

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Identification of N-Acyl Hydrazones as New Non-Zinc-Binding MMP-13 Inhibitors by Structure-Based Virtual Screening Studies and Chemical Optimization

• Authors : Cuffaro, Doretta; Gimeno, Aleix; Bernardoni, Bianca Laura ...

Subjects: MMP-13 inhibitor; N-acyl hydrazone; osteoarthriti

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Identification of a Novel p53 Modulator Endowed with Antitumoural and Antibacterial Activity through a Scaffold Repurposing Approach

• Authors : Nuti, Elisa; La Pietra, Valeria; Daniele, Simona ...

Subjects: Chlamydia trachomati; antibacterial activity; glioblastoma multiforme

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Targeting Aggrecanases for Osteoarthritis Therapy: From Zinc Chelation to Exosite Inhibition

• Authors : Cuffaro, Doretta; Ciccone, Lidia; Rossello, Armando ...

• Source: Journal of Medicinal Chemistry ; volume 65, issue 20, page 13505-13532 ; ISSN 0022-2623 1520-4804

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Exosite inhibition of ADAMTS-5 by a glycoconjugated arylsulfonamide

• Authors : Santamaria, Salvatore; Cuffaro, Doretta; Nuti, Elisa ...

Subjects: Multidisciplinary

• Source: Scientific Reports ; volume 11, issue 1 ; ISSN 2045-2322

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Development of a fluorogenic ADAMTS-7 substrate

• Authors : Santamaria, Salvatore; Buemi, Frederic; Nuti, Elisa ...

• Source: Journal of Enzyme Inhibition and Medicinal Chemistry ; volume 36, issue 1, page 2160-2169 ; ISSN 1475-6366 1475-6374

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Discovery of Dimeric Arylsulfonamides as Potent ADAM8 Inhibitors

• Authors : Cuffaro, Doretta; Camodeca, Caterina; Tuccinardi, Tiziano ...

Subjects: Organic Chemistry; Drug Discovery; Biochemistry

• Source: ACS Medicinal Chemistry Letters ; volume 12, issue 11, page 1787-1793 ; ISSN 1948-5875 1948-5875

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Design and Synthesis of Ionic Liquid-Based Matrix Metalloproteinase Inhibitors (MMPIs): A Simple Approach to Increase Hydrophilicity and to Develop MMPI-Coated Gold Nanoparticles

• Authors : D'Andrea, Felicia; Nuti, Elisa; Becherini, Stefano ...

Subjects: gold nanoparticle; ionic liquid; metalloproteinase

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