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Nelfinavir, Cisplatin, and External Beam Radiation Therapy for the Treatment of Locally Advanced Vulvar Cancer That Cannot Be Removed by Surgery

• Authors : National Cancer Institute (NCI)

• Source: A Phase I Study of Nelfinavir and Cisplatin Chemotherapy Concurrent With Pelvic Radiation for Locally Advanced Vulvar Cancer Not Amenable to Surgical Resection

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Metformin, Nelfinavir, and Bortezomib in Treating Patients With Relapsed and/or Refractory Multiple Myeloma

• Source: An Open-Label Phase 1 Study of Metformin and Nelfinavir in Combination With Bortezomib in Patients With Relapsed and/or Refractory Multiple Myeloma

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Nelfinavir Mesylate in Treating Patients With Kaposi Sarcoma

• Authors : National Cancer Institute (NCI); The Emmes Company, LLC; University of Arkansas

• Source: A Pilot Study of Nelfinavir for the Treatment of Kaposi Sarcoma

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Radiosensitizing Effect of Nelfinavir in Locally Advanced Carcinoma of Cervix (NELCER)

• Authors : Supriya Sastri (chopra), Principal Investigator

• Source: A Phase III Randomized Clinical Trial to Study the Radiosensitizing Effect of Nelfinavir in Locally Advanced Carcinoma of Uterine Cervix.Diehl JA, Cheng M, Roussel

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Stereotactic Radiation, Nelfinavir Mesylate & Neoadjuvant Chemotherapy in Locally Advanced Pancreatic Cancer

• Authors : National Cancer Institute (NCI)

• Source: A Phase 1 Study of Hypofractionated Stereotactic Radiotherapy and Concurrent HIV Protease Inhibitor Nelfinavir as Part of a Neoadjuvant Regimen in Patients With Locally

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Nelfinavir inhibition of Kaposi's sarcoma-associated herpesvirus protein expression and capsid assembly.

• Authors : Li, Maggie¹ (AUTHOR); Smith, Barbara J.² (AUTHOR); Lee, Jaeyeun¹ (AUTHOR)

• Source: Infectious Agents & Cancer. 3/4/2024, Vol. 19 Issue 1, p1-13. 13p.

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Chemotherapy, Stereotactic Body Radiation Therapy & Nelfinavir Mesylate in Locally Advanced Pancreatic Cancer

• Authors : National Cancer Institute (NCI)

• Source: A Phase II Study of Neoadjuvant Chemotherapy With and Without Immunotherapy to CA125 (Oregovomab) Followed by Hypofractionated Stereotactic Radiotherapy & Concurrent HIV Protease Inhibitor

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PPP2R1A silencing suppresses LUAD progression by sensitizing cells to nelfinavir-induced apoptosis and pyroptosis

• Authors : Yating Liu; Lianlian Ouyang; Shiyao Jiang

Subjects: Lung adenocarcinoma; Meiotic genes; Prognostic model

• Source: Cancer Cell International, Vol 24, Iss 1, Pp 1-13 (2024)

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Phase II Trial of Nelfinavir With Concurrent Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck

• Source: A Phase II Trial of a Protease Inhibitor, Nelfinavir (NFV), Given With Definitive, Concurrent Chemoradiotherapy (CTRT) in Patients With Locally-Advanced, Human Papilloma

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Nelfinavir and Lenalidomide/Dexamethasone in Progressive Multiple Myeloma

• Source: Nelfinavir and Lenalidomide/Dexamethasone in Patients With Progressive Multiple Myeloma That Have Failed Lenalidomide-containing Therapy - A Single Arm Phase I/II Trial

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