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Academic Journal

RVFV virulence factor NSs triggers the mitochondrial MCL-1-BAK axis to activate pathogenic NLRP3 pyroptosis.

Authors : Guan Z; State Key Laboratory of Virology, Center for Antiviral Research, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.; University of Chinese Academy of Sciences, Beijing, China.

Subjects: Mitochondria*/Mitochondria*/Mitochondria*/metabolism ; Mitochondria*/Mitochondria*/Mitochondria*/virology ; Myeloid Cell Leukemia Sequence 1 Protein*/Myeloid Cell Leukemia Sequence 1 Protein*/Myeloid Cell Leukemia Sequence 1 Protein*/metabolism

Source: PLoS pathogens [PLoS Pathog] 2024 Aug 30; Vol. 20 (8), pp. e1012387. Date of Electronic Publication: 2024 Aug 30 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

On the mechanism of miR-29b enhancement of etoposide toxicity in vitro.

Authors : Dostál Z; Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czech Republic.; Buchtíková J

Subjects: Etoposide*/Etoposide*/Etoposide*/toxicity ; Etoposide*/Etoposide*/Etoposide*/pharmacology ; MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics

Source: Scientific reports [Sci Rep] 2024 Aug 27; Vol. 14 (1), pp. 19880. Date of Electronic Publication: 2024 Aug 27.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Altered neutrophil responses to dengue virus serotype three: delayed apoptosis is regulated by stabilisation of Mcl-1.

Authors : Kamsom C; Department of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.; Edwards SW

Subjects: Dengue Virus*/Dengue Virus*/Dengue Virus*/physiology ; Neutrophils*/Neutrophils*/Neutrophils*/immunology ; Neutrophils*/Neutrophils*/Neutrophils*/metabolism

Source: Scientific reports [Sci Rep] 2024 Aug 08; Vol. 14 (1), pp. 18414. Date of Electronic Publication: 2024 Aug 08.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Vitamin K2 sensitizes the efficacy of venetoclax in acute myeloid leukemia by targeting the NOXA-MCL-1 pathway.

Authors : Tauchi T; Shinyurigaoka General Hospital, Asou-ku, Kawasaki, Kanagawa, Japan.; Moriya S

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/drug therapy ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/metabolism ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/genetics

Source: PloS one [PLoS One] 2024 Jul 25; Vol. 19 (7), pp. e0307662. Date of Electronic Publication: 2024 Jul 25 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Evaluation of MCL-1 as a prognostic factor in canine mammary gland tumors.

Authors : Cho J; Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, Republic of Korea.; Chung H

Subjects: Myeloid Cell Leukemia Sequence 1 Protein*/Myeloid Cell Leukemia Sequence 1 Protein*/Myeloid Cell Leukemia Sequence 1 Protein*/metabolism ; Mammary Neoplasms, Animal*/Mammary Neoplasms, Animal*/Mammary Neoplasms, Animal*/metabolism ; Mammary Neoplasms, Animal*/Mammary Neoplasms, Animal*/Mammary Neoplasms, Animal*/pathology

Source: PloS one [PLoS One] 2024 Jul 16; Vol. 19 (7), pp. e0306398. Date of Electronic Publication: 2024 Jul 16 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Low BCL-xL expression in triple-negative breast cancer cells favors chemotherapy efficacy, and this effect is limited by cancer-associated fibroblasts.

Authors : Nocquet L; INSERM, CNRS, CRCI2NA, Université de Nantes, 44000, Nantes, France.; Equipe Labellisée LIGUE Contre le Cancer, Paris, France.

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/drug therapy ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/metabolism ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/genetics

Source: Scientific reports [Sci Rep] 2024 Jun 19; Vol. 14 (1), pp. 14177. Date of Electronic Publication: 2024 Jun 19.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Modeling the Binding of Anticancer Peptides and Mcl-1.

Authors : Alhammadi SHA; Department of Biology, College of Science, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.; Baby B

Subjects: Myeloid Cell Leukemia Sequence 1 Protein*/Myeloid Cell Leukemia Sequence 1 Protein*/Myeloid Cell Leukemia Sequence 1 Protein*/metabolism ; Myeloid Cell Leukemia Sequence 1 Protein*/Myeloid Cell Leukemia Sequence 1 Protein*/Myeloid Cell Leukemia Sequence 1 Protein*/chemistry ; Protein Binding*

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 13; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Mcl-1 Protein and Viral Infections: A Narrative Review.

Authors : Wyżewski Z; Institute of Biological Sciences, Cardinal Stefan Wyszyński University in Warsaw, Dewajtis 5, 01-815 Warsaw, Poland.; Stępkowska J

Subjects: Myeloid Cell Leukemia Sequence 1 Protein* ; Virus Diseases*; Humans

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 17; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Inhibition of Mcl-1 Synergistically Enhances the Antileukemic Activity of Gilteritinib and MRX-2843 in Preclinical Models of FLT3 -Mutated Acute Myeloid Leukemia.

Authors : Wu S; Department of Pediatric Hematology, The First Hospital of Jilin University, Changchun 130021, China.; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun 130012, China.

Subjects: fms-Like Tyrosine Kinase 3*/fms-Like Tyrosine Kinase 3*/fms-Like Tyrosine Kinase 3*/genetics ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/drug therapy ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/genetics

Source: Cells [Cells] 2022 Sep 03; Vol. 11 (17). Date of Electronic Publication: 2022 Sep 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Inhibition of MCL1 induces apoptosis in anaplastic large cell lymphoma and in primary effusion lymphoma.

Authors : Quentmeier H; Department of Human and Animal Cell Lines, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Inhoffenstr. 7B, 38124, Braunschweig, Germany. .; Geffers R

Subjects: Lymphoma, Large-Cell, Anaplastic/Lymphoma, Large-Cell, Anaplastic/Lymphoma, Large-Cell, Anaplastic/*metabolism ; Lymphoma, Primary Effusion/Lymphoma, Primary Effusion/Lymphoma, Primary Effusion/*metabolism ; Myeloid Cell Leukemia Sequence 1 Protein/Myeloid Cell Leukemia Sequence 1 Protein/Myeloid Cell Leukemia Sequence 1 Protein/*metabolism

Source: Scientific reports [Sci Rep] 2022 Jan 20; Vol. 12 (1), pp. 1085. Date of Electronic Publication: 2022 Jan 20.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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نتائج البحث

فلترة النتائج

RVFV virulence factor NSs triggers the mitochondrial MCL-1-BAK axis to activate pathogenic NLRP3 pyroptosis.

On the mechanism of miR-29b enhancement of etoposide toxicity in vitro.

Altered neutrophil responses to dengue virus serotype three: delayed apoptosis is regulated by stabilisation of Mcl-1.

Vitamin K2 sensitizes the efficacy of venetoclax in acute myeloid leukemia by targeting the NOXA-MCL-1 pathway.

Evaluation of MCL-1 as a prognostic factor in canine mammary gland tumors.

Low BCL-xL expression in triple-negative breast cancer cells favors chemotherapy efficacy, and this effect is limited by cancer-associated fibroblasts.

Modeling the Binding of Anticancer Peptides and Mcl-1.

Mcl-1 Protein and Viral Infections: A Narrative Review.

Inhibition of Mcl-1 Synergistically Enhances the Antileukemic Activity of Gilteritinib and MRX-2843 in Preclinical Models of FLT3 -Mutated Acute Myeloid Leukemia.

Inhibition of MCL1 induces apoptosis in anaplastic large cell lymphoma and in primary effusion lymphoma.

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