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  • 1-10 ل  15,004 نتائج ل ""Mice, Inbred NOD""
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Academic Journal

Enhancing anti-CD3 mAb-mediated diabetes remission in autoimmune diabetes through regulation of dynamin-related protein 1(Drp1)-mediated mitochondrial dynamics in exhausted CD8 + T-cell subpopulations.

  • Authors : Zhao R; Department of Endocrinology, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu Province, China.; Su Z

Subjects: CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/immunology ; CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/drug effects ; CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/metabolism

  • Source: BMC medicine [BMC Med] 2025 Mar 31; Vol. 23 (1), pp. 189. Date of Electronic Publication: 2025 Mar 31.Publisher: BioMed Central Country of Publication: England NLM ID: 101190723 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7015

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Academic Journal

Metformin prevents diabetes development in type 1 diabetes models via suppression of mTOR and STAT3 signaling in immune cells.

  • Authors : Suzuki H; Division of Health Sciences, Department of Public Health, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Suma-ku, Kobe, 654-0142, Japan.; Hasegawa S

Subjects: Metformin*/Metformin*/Metformin*/pharmacology ; Diabetes Mellitus, Type 1*/Diabetes Mellitus, Type 1*/Diabetes Mellitus, Type 1*/prevention & control ; Diabetes Mellitus, Type 1*/Diabetes Mellitus, Type 1*/Diabetes Mellitus, Type 1*/metabolism

  • Source: Scientific reports [Sci Rep] 2025 Mar 27; Vol. 15 (1), pp. 10641. Date of Electronic Publication: 2025 Mar 27.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Single-cell RNA-seq reveals disease-specific CD8+ T cell clonal expansion and a high frequency of transcriptionally distinct double-negative T cells in diabetic NOD mice.

  • Authors : Islam MZ; Section on Pathophysiology and Molecular Pharmacology, Joslin Diabetes Center, Boston, Massachusetts, United States of America.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America.

Subjects: Mice, Inbred NOD* ; CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/immunology ; CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/metabolism

  • Source: PloS one [PLoS One] 2025 Mar 19; Vol. 20 (3), pp. e0317987. Date of Electronic Publication: 2025 Mar 19 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

β-Cell Deletion of Hypoxia-Inducible Factor 1α (HIF-1α) Increases Pancreatic β-Cell Susceptibility to Streptozotocin.

  • Authors : Yu J; Centre for Diabetes, Obesity and Endocrinology (CDOE), The Westmead Institute for Medical Research, The University of Sydney, Sydney, NSW 2145, Australia.; Lalwani A

Subjects: Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/genetics ; Insulin-Secreting Cells*/Insulin-Secreting Cells*/Insulin-Secreting Cells*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 15; Vol. 25 (24). Date of Electronic Publication: 2024 Dec 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Development of a spontaneous model of renal interstitial fibrosis in NOD/SCID mice: Aging-induced pathogenesis.

  • Authors : Qiu L; Yunnan Key Laboratory for Basic Research on Bone and Joint Diseases, Kunming University, Kunming, China.; Ma Z

Subjects: Fibrosis* ; Disease Models, Animal* ; Mice, Inbred NOD*

  • Source: PloS one [PLoS One] 2024 Dec 11; Vol. 19 (12), pp. e0315437. Date of Electronic Publication: 2024 Dec 11 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

A tumorigenicity evaluation platform for cell therapies based on brain organoids.

  • Authors : Xue J; Department of Neurosurgery, Huashan Hospital, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200040, China.; National Center for Neurological Disorders, Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Huashan Hospital, Fudan University, Shanghai, 200040, China.

Subjects: Organoids* ; Mice, SCID* ; Pluripotent Stem Cells*

  • Source: Translational neurodegeneration [Transl Neurodegener] 2024 Oct 29; Vol. 13 (1), pp. 53. Date of Electronic Publication: 2024 Oct 29.Publisher: BioMed Central Country of Publication: England NLM ID: 101591861 Publication Model: Electronic Cited Medium: Print ISSN: 2047-9158

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Academic Journal

Mucosal Addressin Cell Adhesion Molecule-1 Mediates T Cell Migration into Pancreas-Draining Lymph Nodes for Initiation of the Autoimmune Response in Type 1 Diabetes.

  • Authors : Li Y; Department of Vascular Surgery, Tianjin Medical University Second Hospital, Tianjin 300211, China.; Department of Pathology, School of Medicine, Stanford University, Stanford, CA 94305, USA.

Subjects: Diabetes Mellitus, Type 1*/Diabetes Mellitus, Type 1*/Diabetes Mellitus, Type 1*/immunology ; Diabetes Mellitus, Type 1*/Diabetes Mellitus, Type 1*/Diabetes Mellitus, Type 1*/metabolism ; Diabetes Mellitus, Type 1*/Diabetes Mellitus, Type 1*/Diabetes Mellitus, Type 1*/pathology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 22; Vol. 25 (21). Date of Electronic Publication: 2024 Oct 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Type 1 diabetes and parasite infection: An exploratory study in NOD mice.

  • Authors : Giraud E; Chemogenomic and Biological Screening Core Facility, C2RT, CNRS UMR 3523, Institut Pasteur, Université Paris Cité, Paris, France.; Fiette L

Subjects: Diabetes Mellitus, Type 1*/Diabetes Mellitus, Type 1*/Diabetes Mellitus, Type 1*/immunology ; Diabetes Mellitus, Type 1*/Diabetes Mellitus, Type 1*/Diabetes Mellitus, Type 1*/parasitology ; Mice, Inbred NOD*

  • Source: PloS one [PLoS One] 2024 Oct 22; Vol. 19 (10), pp. e0308868. Date of Electronic Publication: 2024 Oct 22 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Characterizing the Cell-Free Transcriptome in a Humanized Diffuse Large B-Cell Lymphoma Patient-Derived Tumor Xenograft Model for RNA-Based Liquid Biopsy in a Preclinical Setting.

  • Authors : Decruyenaere P; Department of Hematology, Ghent University Hospital, 9000 Ghent, Belgium.; OncoRNALab, Cancer Research Institute Ghent (CRIG), Ghent University, 9000 Ghent, Belgium.

Subjects: Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/genetics ; Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/pathology ; Cyclophosphamide*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Sep 16; Vol. 25 (18). Date of Electronic Publication: 2024 Sep 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Dynamic changes in immune cells in humanized liver metastasis and subcutaneous xenograft mouse models.

  • Authors : Bang HJ; Division of Hematology-Oncology, Department of Internal Medicine, Chonnam National University Medical School and Hwasun Hospital, 322 Seoyang-Ro, Hwasun-Eup, Hwasun-Gun, Jeollanam-Do, 58128, Republic of Korea.; Lee KH

Subjects: Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/secondary ; Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/immunology ; Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/pathology

  • Source: Scientific reports [Sci Rep] 2024 Sep 02; Vol. 14 (1), pp. 20338. Date of Electronic Publication: 2024 Sep 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 ل  15,004 نتائج ل ""Mice, Inbred NOD""