نتائج البحث

KIF1C facilitates retrograde transport of lysosomes through Hook3 and dynein.

• Authors : Saji, Takeshi¹ (AUTHOR); Endo, Mitsuharu² (AUTHOR); Okada, Yasushi^3,4,5,6 (AUTHOR)

• Source: Communications Biology. 10/11/2024, Vol. 7 Issue 1, p1-12. 12p.

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St-N, a novel alkaline derivative of stevioside, reverses docetaxel resistance by targeting lysosomes in vitro and in vivo.

• Authors : Guo Y; Department of Central Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.; Engineering Laboratory of Urinary Organ and Functional Reconstruction of Shandong Province, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.

Subjects: Lysosomes*/Lysosomes*/Lysosomes*/drug effects ; Lysosomes*/Lysosomes*/Lysosomes*/metabolism ; Docetaxel*/Docetaxel*/Docetaxel*/pharmacology

• Source: PloS one [PLoS One] 2024 Dec 27; Vol. 19 (12), pp. e0316268. Date of Electronic Publication: 2024 Dec 27 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Deficiency in NPC2 results in disruption of mitochondria-late endosome/lysosomes contact sites and endo-lysosomal lipid dyshomeostasis.

• Authors : Pastore R; MSD R&D Innovation Centre, 120 Moorgate, London, EC2M 6UR, UK.; Department of Medicine and Health Sciences 'Vincenzo Tiberio', University of Molise, via F. De Santis, 86100, Campobasso, Italy.

Subjects: Lysosomes*/Lysosomes*/Lysosomes*/metabolism ; Endosomes*/Endosomes*/Endosomes*/metabolism ; Mitochondria*/Mitochondria*/Mitochondria*/metabolism

• Source: Scientific reports [Sci Rep] 2025 Jan 02; Vol. 15 (1), pp. 325. Date of Electronic Publication: 2025 Jan 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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NKX3-2 Induces Ovarian Cancer Cell Migration by HDAC6-Mediated Repositioning of Lysosomes and Inhibition of Autophagy.

• Authors : Ferraresi A; Laboratory of Molecular Pathology, Department of Health Sciences, Università del Piemonte Orientale 'A. Avogadro', Via Solaroli 17, 28100 Novara, Italy.; Ghezzi I

Subjects: Autophagy*/Autophagy*/Autophagy*/drug effects ; Autophagy*/Autophagy*/Autophagy*/genetics ; Cell Movement*/Cell Movement*/Cell Movement*/genetics

• Source: Cells [Cells] 2024 Nov 04; Vol. 13 (21). Date of Electronic Publication: 2024 Nov 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes.

• Authors : Rose, Kevin; Jepson, Tyler; Shukla, Sankalp

Subjects: Alzheimer’s disease; ESCRT; STORM

• Source: Proceedings of the National Academy of Sciences. 121(22)

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CUL-6/cullin ubiquitin ligase-mediated degradation of HSP-90 by intestinal lysosomes promotes thermotolerance

• Authors : Sarmiento, Mario Bardan; Gang, Spencer S; van Oosten-Hawle, Patricija

Subjects: Biochemistry and Cell Biology; Biological Sciences; Animals

• Source: Cell Reports. 43(6)

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Calcium signaling from damaged lysosomes induces cytoprotective stress granules.

• Authors : Duran, Jacob; Salinas, Jay; Wheaton, Rui

Subjects: ALG2-ALIX; Calcium-dependent Pathway; Lysosomal Damage

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RILP Induces Cholesterol Accumulation in Lysosomes by Inhibiting Endoplasmic Reticulum-Endolysosome Interactions.

• Authors : Han Y; State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Fujian Provincial Key Laboratory of Innovative Drug Target Research, Xiamen University, Xiamen 361102, China.; Liu X

Subjects: Lysosomes*/Lysosomes*/Lysosomes*/metabolism ; Cholesterol*/Cholesterol*/Cholesterol*/metabolism ; Endoplasmic Reticulum*/Endoplasmic Reticulum*/Endoplasmic Reticulum*/metabolism

• Source: Cells [Cells] 2024 Aug 06; Vol. 13 (16). Date of Electronic Publication: 2024 Aug 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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One size does not fit all: Lysosomes exist in biochemically and functionally distinct states.

• Authors : Bussi, Claudio¹ (AUTHOR) ; Gutierrez, Maximiliano G.¹ (AUTHOR)

• Source: PLoS Biology. 3/22/2024, Vol. 22 Issue 3, p1-5. 5p.

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Defects of mitochondria-lysosomes communication induce secretion of mitochondria-derived vesicles and drive chemoresistance in ovarian cancer cells.

• Authors : Gagliardi, Sinforosa¹ (AUTHOR); Mitruccio, Marco¹ (AUTHOR); Di Corato, Riccardo^2,3 (AUTHOR)

• Source: Cell Communication & Signaling. 3/6/2024, Vol. 22 Issue 1, p1-26. 26p.

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