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Academic Journal

Locus coeruleus tau validates and informs high-resolution MRI in aging and at earliest Alzheimer's pathology stages.

  • Authors : Hary AT; Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 Thirteenth St, Suite 2301, Charlestown, MA, 02129, USA.; Chadha S

Subjects: Locus Coeruleus*/Locus Coeruleus*/Locus Coeruleus*/pathology ; Locus Coeruleus*/Locus Coeruleus*/Locus Coeruleus*/diagnostic imaging ; Locus Coeruleus*/Locus Coeruleus*/Locus Coeruleus*/metabolism

  • Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2025 Feb 28; Vol. 13 (1), pp. 44. Date of Electronic Publication: 2025 Feb 28.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960

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Academic Journal

Impact of noradrenergic inhibition on neuroinflammation and pathophysiology in mouse models of Alzheimer's disease.

  • Authors : Evans AK; Department of Neurosurgery, Stanford University School of Medicine, 1050 Arastradero Road, Building A, Palo Alto, Stanford, CA, 94304, United States of America.; Park HH

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2024 Dec 18; Vol. 21 (1), pp. 322. Date of Electronic Publication: 2024 Dec 18.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Academic Journal

Spared nerve injury leads to reduced activity of neurons projecting from the ventrolateral periaqueductal gray to the locus coeruleus.

  • Authors : Yu WL; Department of Clinical Neurosciences, Cuming School of Medicine, Hotchkiss Brain Institute and Alberta Children's Hospital Research Institute, University of Calgary, 3330 Hospital Drive, Calgary, T2N4N1, Canada.; Zhang Z

Subjects: Periaqueductal Gray*/Periaqueductal Gray*/Periaqueductal Gray*/physiopathology ; Periaqueductal Gray*/Periaqueductal Gray*/Periaqueductal Gray*/physiology ; Locus Coeruleus*/Locus Coeruleus*/Locus Coeruleus*/physiopathology

  • Source: Molecular brain [Mol Brain] 2024 Jul 24; Vol. 17 (1), pp. 46. Date of Electronic Publication: 2024 Jul 24.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606

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Academic Journal

Lower in vivo locus coeruleus integrity is associated with lower cortical thickness in older individuals with elevated Alzheimer's pathology: a cohort study.

  • Authors : Engels-Domínguez N; The Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA.; Faculty of Health, Medicine and Life Sciences, School for Mental Health and Neuroscience, Alzheimer Centre Limburg, Maastricht University, Maastricht, The Netherlands.

Subjects: Locus Coeruleus*/Locus Coeruleus*/Locus Coeruleus*/diagnostic imaging ; Locus Coeruleus*/Locus Coeruleus*/Locus Coeruleus*/pathology ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/diagnostic imaging

  • Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2024 Jun 17; Vol. 16 (1), pp. 129. Date of Electronic Publication: 2024 Jun 17.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Locus coeruleus integrity and left frontoparietal connectivity provide resilience against attentional decline in preclinical alzheimer's disease.

  • Authors : Pahl J; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Department of Neurology, University Hospital RWTH Aachen, Aachen, Germany.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/diagnostic imaging ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/psychology ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/physiopathology

  • Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2024 May 31; Vol. 16 (1), pp. 119. Date of Electronic Publication: 2024 May 31.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Combined in vivo MRI assessment of locus coeruleus and nucleus basalis of Meynert integrity in amnestic Alzheimer's disease, suspected-LATE and frontotemporal dementia.

  • Authors : Lagarde J; Department of Neurology of Memory and Language, GHU Paris Psychiatry and Neurosciences, Hôpital Sainte Anne, Paris, France. .; Université Paris-Saclay, Service Hospitalier Frédéric Joliot CEA, CNRS, Inserm, BioMaps, Orsay, F- 91401, France. .

Subjects: Frontotemporal Dementia*/Frontotemporal Dementia*/Frontotemporal Dementia*/diagnostic imaging ; Frontotemporal Dementia*/Frontotemporal Dementia*/Frontotemporal Dementia*/pathology ; Locus Coeruleus*/Locus Coeruleus*/Locus Coeruleus*/diagnostic imaging

  • Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2024 May 03; Vol. 16 (1), pp. 97. Date of Electronic Publication: 2024 May 03.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Microstructural integrity of the locus coeruleus and its tracts reflect noradrenergic degeneration in Alzheimer's disease and Parkinson's disease.

  • Authors : Lin CP; Amsterdam UMC, Department of Anatomy and Neurosciences, Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. .; Amsterdam Neuroscience, Brain imaging, Amsterdam, The Netherlands. .

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/diagnostic imaging ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/diagnostic imaging

  • Source: Translational neurodegeneration [Transl Neurodegener] 2024 Feb 09; Vol. 13 (1), pp. 9. Date of Electronic Publication: 2024 Feb 09.Publisher: BioMed Central Country of Publication: England NLM ID: 101591861 Publication Model: Electronic Cited Medium: Print ISSN: 2047-9158

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Academic Journal

Sexual differences in locus coeruleus neurons and related behavior in C57BL/6J mice.

  • Authors : Mariscal P; Neuropsychopharmacology & Psychobiology Research Group, Department of Neuroscience, University of Cádiz, 11003, Cádiz, Spain.; Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Instituto de Salud Carlos III, 28029, Madrid, Spain.

Subjects: Locus Coeruleus*/Locus Coeruleus*/Locus Coeruleus*/pathology ; Locus Coeruleus*/Locus Coeruleus*/Locus Coeruleus*/physiology ; Neurons*/Neurons*/Neurons*/physiology

  • Source: Biology of sex differences [Biol Sex Differ] 2023 Sep 28; Vol. 14 (1), pp. 64. Date of Electronic Publication: 2023 Sep 28.Publisher: BioMed Central Country of Publication: England NLM ID: 101548963 Publication Model: Electronic Cited Medium: Internet ISSN: 2042-6410

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Academic Journal

The locus coeruleus input to the rostral ventromedial medulla mediates stress-induced colorectal visceral pain.

  • Authors : Kong D; Department of Anesthesiology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200127, China.; Key Laboratory of Anesthesiology (Shanghai Jiao Tong University), Ministry of Education, Shanghai, China.

Subjects: Visceral Pain*/Visceral Pain*/Visceral Pain*/pathology ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/pathology; Rats

  • Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Apr 17; Vol. 11 (1), pp. 65. Date of Electronic Publication: 2023 Apr 17.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960

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Academic Journal

In vivo detection of substantia nigra and locus coeruleus volume loss in Parkinson's disease using neuromelanin-sensitive MRI: Replication in two cohorts.

  • Authors : Hwang KS; Department of Neurosciences, University of California San Diego, San Diego, California, United States of America.; Langley J

Subjects: Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/diagnostic imaging ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/pathology; Humans

  • Source: PloS one [PLoS One] 2023 Apr 13; Vol. 18 (4), pp. e0282684. Date of Electronic Publication: 2023 Apr 13 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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