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Protective Efficacy of Monoclonal Antibodies Neutralizing Alpha-Hemolysin and Bicomponent Leukocidins in a Rabbit Model of Staphylococcus aureus Necrotizing Pneumonia.

• Authors : Vu, Trang TT; Nguyen, Nhu TQ; Tran, Vuvi G

Subjects: Pneumonia & Influenza; Emerging Infectious Diseases; Biotechnology

• Source: Antimicrobial Agents and Chemotherapy. 64(3)

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Panton-Valentine Leukocidin-Positive Staphylococcus aureus in Family and Pet Cat.

• Authors : Bethe A; Schink AK; Brombach J

Subjects: Leukocidins*/Leukocidins*/Leukocidins*/genetics ; Exotoxins*/Exotoxins*/Exotoxins*/genetics ; Bacterial Toxins*/Bacterial Toxins*/Bacterial Toxins*/genetics

• Source: Emerging infectious diseases [Emerg Infect Dis] 2024 Aug; Vol. 30 (8), pp. 1724-1726.Publisher: National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC) Country of Publication: United States NLM ID: 9508155

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Panton-Valentine leucocidin gene in methicillin resistant Staphylococcus aureus isolated from tertiary care hospital in Nepal.

• Authors : Syangtan G; Shi-Gan International College of Science and Technology, Tribhuvan University, Kathmandu, Nepal.; Khanal LK

Subjects: Leukocidins*/Leukocidins*/Leukocidins*/genetics ; Exotoxins*/Exotoxins*/Exotoxins*/genetics ; Methicillin-Resistant Staphylococcus aureus*/Methicillin-Resistant Staphylococcus aureus*/Methicillin-Resistant Staphylococcus aureus*/genetics

• Source: Journal of infection in developing countries [J Infect Dev Ctries] 2024 Jul 29; Vol. 18 (7), pp. 1010-1019. Date of Electronic Publication: 2024 Jul 29.Publisher: Open Learning on Enteric Pathogens Country of Publication: Italy NLM ID: 101305410 Publication Model: Electronic Cited Medium: Internet

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In Vivo Gene Expression Profiling of Staphylococcus aureus during Infection Informs Design of Stemless Leukocidins LukE and -D as Detoxified Vaccine Candidates

• Authors : Andreas F. Haag; Lassi Liljeroos; Paolo Donato

Subjects: in vivo gene expression; high-throughput qRT-PCR; Staphylococcus aureus

• Source: Microbiology Spectrum, Vol 11, Iss 1 (2023)

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Cellular factors involved in the cytotoxicity of Staphylococcus aureus leukocidins: novel therapeutic targets

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Monoclonal antibodies neutralizing alpha-hemolysin, bicomponent leukocidins, and clumping factor A protected against Staphylococcus aureus-induced acute circulatory failure in a mechanically ventilated rabbit model of hyperdynamic septic shock

• Authors : Nhu T. Q. Nguyen; Thien N. M. Doan; Kei Sato

Subjects: Staphylococcus aureus; mechanical ventilated rabbit model; hyperdynamic septic shock

• Source: Frontiers in Immunology, Vol 14 (2023)

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Improved Protection in a Rabbit Model of Community-Associated Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia upon Neutralization of Leukocidins in Addition to Alpha-Hemolysin

• Authors : Diep, Binh An; Le, Vien TM; Visram, Zehra C

Subjects: Microbiology; Biological Sciences; Biomedical and Clinical Sciences

• Source: Antimicrobial Agents and Chemotherapy. 60(10)

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STAPHYLOCOCCUS AUREUS LEUKOCIDINS, THERAPEUTIC COMPOSITIONS, AND USES THEREOF

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Novel human monoclonal antibodies targeting the F subunit of leukocidins reduce disease progression and mortality caused by Staphylococcus aureus

• Authors : Chendi Jing; Chenghua Liu; Fangjie Liu

Subjects: Staphylococcus aureus; Leukocidins; Human monoclonal antibodies

• Source: BMC Microbiology, Vol 18, Iss 1, Pp 1-10 (2018)

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Novel human monoclonal antibodies targeting the F subunit of leukocidins reduce disease progression and mortality caused by Staphylococcus aureus.

• Authors : Jing C; Department of Infectious Diseases, Peking University First Hospital, Beijing, 100034, China.; Liu C

Subjects: Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*administration & dosage ; Hemolysin Proteins/Hemolysin Proteins/Hemolysin Proteins/*immunology ; Leukocidins/Leukocidins/Leukocidins/*immunology

• Source: BMC microbiology [BMC Microbiol] 2018 Nov 12; Vol. 18 (1), pp. 181. Date of Electronic Publication: 2018 Nov 12.Publisher: BioMed Central Country of Publication: England NLM ID: 100966981 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2180

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