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  • 1-10 ل  6,563 نتائج ل ""Kidney Tubules, Proximal""
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Academic Journal

The PKM2 activator TEPP-46 suppresses cellular senescence in hydrogen peroxide-induced proximal tubular cells and kidney fibrosis in CD-1 db/db mice.

  • Authors : Ishihara SI; Faculty of Medicine, Internal Medicine, Shimane University, Izumo, Shimane, Japan.; Kayes MI

Subjects: Cellular Senescence*/Cellular Senescence*/Cellular Senescence*/drug effects ; Hydrogen Peroxide*/Hydrogen Peroxide*/Hydrogen Peroxide*/pharmacology ; Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/drug effects

  • Source: Journal of diabetes investigation [J Diabetes Investig] 2025 Apr; Vol. 16 (4), pp. 598-607. Date of Electronic Publication: 2025 Jan 22.Publisher: Asian Association for the Study of Diabetes and Blackwell Pub. Asia Country of Publication: Japan NLM ID: 101520702 Publication Model:

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Academic Journal

Metabolite pathway alterations identified by magnetic resonance metabolomics in a proximal tubular epithelial cell line treated with TGF-β1.

  • Authors : Humphries TLR; Kidney Disease Research Collaborative, The University of Queensland and Translational Research Institute, Brisbane, Queensland, Australia.; School of Biomedical Sciences, Macgregor Building, The University of Queensland, St Lucia, Queensland, Australia.

Subjects: Transforming Growth Factor beta1*/Transforming Growth Factor beta1*/Transforming Growth Factor beta1*/metabolism ; Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/metabolism ; Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/cytology

  • Source: Physiological reports [Physiol Rep] 2025 Feb; Vol. 13 (4), pp. e70249.Publisher: published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society Country of Publication: United States NLM

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Academic Journal

GPX4 expression changes in proximal tubule cells highlight the role of ferroptosis in IgAN.

  • Authors : Qing J; Department of Nephrology, Shanxi Provincial People's Hospital (Fifth Hospital), Shanxi Medical University, Taiyuan, 030001, China.; Department of Nephrology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, China.

Subjects: Ferroptosis*/Ferroptosis*/Ferroptosis*/genetics ; Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/metabolism ; Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/pathology

  • Source: Scientific reports [Sci Rep] 2025 Jan 31; Vol. 15 (1), pp. 3886. Date of Electronic Publication: 2025 Jan 31.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

High glucose couples DJ-1 with PTEN to activate PDGFRβ for renal proximal tubular cell injury.

  • Authors : Das F; VA Research, Education and Clinical Center, South Texas Veterans Health Care System, San Antonio, Texas, United States of America.; Departments of Medicine, UT Health San Antonio, San Antonio, Texas, United States of America.

Subjects: PTEN Phosphohydrolase*/PTEN Phosphohydrolase*/PTEN Phosphohydrolase*/metabolism ; PTEN Phosphohydrolase*/PTEN Phosphohydrolase*/PTEN Phosphohydrolase*/genetics ; Protein Deglycase DJ-1*/Protein Deglycase DJ-1*/Protein Deglycase DJ-1*/metabolism

  • Source: PloS one [PLoS One] 2025 Jan 06; Vol. 20 (1), pp. e0311828. Date of Electronic Publication: 2025 Jan 06 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Chiral Amino Acids Mediate Mitochondria-Dependent Apoptosis of Human Proximal Tubular Epithelial Cells Under Oxidative Stress.

  • Authors : Lu Y; School of Chemical Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.; Zhang Y

Subjects: Oxidative Stress* ; Apoptosis* ; Mitochondria*/Mitochondria*/Mitochondria*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 15; Vol. 25 (24). Date of Electronic Publication: 2024 Dec 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Sirtuin1 Suppresses Calcium Oxalate Nephropathy via Inhibition of Renal Proximal Tubular Cell Ferroptosis Through PGC-1α-mediated Transcriptional Coactivation.

  • Authors : Duan C; Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, China.; Tumor Precision Diagnosis and Treatment Technology and Translational Medicine, Hubei Engineering Research Center, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, China.

Subjects: Ferroptosis*/Ferroptosis*/Ferroptosis*/drug effects ; Ferroptosis*/Ferroptosis*/Ferroptosis*/genetics ; Sirtuin 1*/Sirtuin 1*/Sirtuin 1*/metabolism

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Dec; Vol. 11 (48), pp. e2408945. Date of Electronic Publication: 2024 Nov 05.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

Tanshinone I improves renal fibrosis by promoting gluconeogenesis through upregulation of peroxisome proliferator-activated receptor-γ coactivator 1α.

  • Authors : Bai Y; Department of Nephrology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.; TCM Institute of Kidney Disease of Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Subjects: Renal Insufficiency, Chronic*/Renal Insufficiency, Chronic*/Renal Insufficiency, Chronic*/drug therapy ; Renal Insufficiency, Chronic*/Renal Insufficiency, Chronic*/Renal Insufficiency, Chronic*/pathology ; Antifibrotic Agents*/Antifibrotic Agents*/Antifibrotic Agents*/pharmacology

  • Source: Renal failure [Ren Fail] 2024 Dec; Vol. 46 (2), pp. 2433710. Date of Electronic Publication: 2024 Dec 08.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

SGLT2 inhibitor dapagliflozin reduces proximal tubular cell damage biomarkers in patients with acute heart failure.

  • Authors : Gojaseni P; Division of Nephrology, Department of Medicine, Bhumibol Adulyadej Hospital, Directorate of Medical Services, Royal Thai Air Force, Bangkok, Thailand.; Wattanakul J

Subjects: Benzhydryl Compounds*/Benzhydryl Compounds*/Benzhydryl Compounds*/therapeutic use ; Biomarkers*/Biomarkers*/Biomarkers*/blood ; Glucosides*/Glucosides*/Glucosides*/therapeutic use

  • Source: Renal failure [Ren Fail] 2024 Dec; Vol. 46 (2), pp. 2373275. Date of Electronic Publication: 2024 Jul 05.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Proximal tubule cell maturation rate and function are controlled by PPARα signaling in kidney organoids.

  • Authors : Sahara Y; RIKEN Center for Biosystems Dynamics Research, Kobe, 650-0047, Japan.; Laboratory of Molecular Cell Biology and Development, Department of Animal Development and Physiology, Graduate School of Biostudies, Kyoto University, Kyoto, 606-8501, Japan.

Subjects: Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/metabolism ; Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/cytology ; Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/drug effects

  • Source: Communications biology [Commun Biol] 2024 Nov 27; Vol. 7 (1), pp. 1532. Date of Electronic Publication: 2024 Nov 27.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Massive entry of BK Polyomavirus induces transient cytoplasmic vacuolization of human renal proximal tubule epithelial cells.

  • Authors : Lorentzen EM; Department of Microbiology and Infection Control, University Hospital of North Norway, Tromsø, Norway.; Metabolic and Renal Research Group, Department of Clinical Medicine, UiT-The Arctic University of Norway, Tromsø, Norway.

Subjects: Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/virology ; Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/metabolism ; Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/pathology

  • Source: PLoS pathogens [PLoS Pathog] 2024 Nov 21; Vol. 20 (11), pp. e1012681. Date of Electronic Publication: 2024 Nov 21 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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  • 1-10 ل  6,563 نتائج ل ""Kidney Tubules, Proximal""