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Two phase 3 trials of inclisiran in patients with elevated LDL cholesterol

• Authors : Ray K. K.; Wright R. S.; Kallend D. ...

Subjects: aged; 80 and over; anticholesteremic agent

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Pooled safety and efficacy of inclisiran in patients with statin intolerance (ORION-10 and ORION-11)

• Authors : Wright, R.S; Kallend, D; Raal, F.J

Subjects: Cardiology and Cardiovascular Medicine

• Source: European Heart Journal ; volume 41, issue Supplement_2 ; ISSN 0195-668X 1522-9645

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Inter-individual variability in LDL-C reductions with inclisiran – data from ORION-10 and ORION-11

• Authors : Wright, R.S; Raal, F.J; Kallend, D

Subjects: Cardiology and Cardiovascular Medicine

• Source: European Heart Journal ; volume 41, issue Supplement_2 ; ISSN 0195-668X 1522-9645

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Aldosterone does not predict cardiovascular events following acute coronary syndrome in patients initially without heart failure

• Authors : Pitts, R; Gunzburger, E; Ballantyne, CM

Subjects: Heart Disease; Cardiovascular; Clinical Trials and Supportive Activities

• Source: urn:ISSN:2047-9980 ; Journal of the American Heart Association, 6, 1, e004119

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MDCO-216 Does Not Induce Adverse Immunostimulation, in Contrast to Its Predecessor ETC-216

• Authors : Reijers, Joannes A. A.; Kallend, D. G.; Malone, K. E. ...

Subjects: Pharmacology (medical); Cardiology and Cardiovascular Medicine; Pharmacology

• Source: Cardiovascular Drugs and Therapy ; volume 31, issue 4, page 381-389 ; ISSN 0920-3206 1573-7241

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The N-Acetylgalactosamine-conjugated small interfering RNA inclisiran can be coadministered safely with atorvastatin in cynomolgus monkeys resulting in additive low-density lipoprotein cholesterol reductions.

• Authors : Lehoux D; Targanta Therapeutics Inc., Saint Laurent, Quebec, Canada.; Kallend D

Subjects: Anticholesteremic Agents*/Anticholesteremic Agents*/Anticholesteremic Agents*/adverse effects ; Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use; Animals

• Source: Pharmacology research & perspectives [Pharmacol Res Perspect] 2023 Apr; Vol. 11 (2), pp. e01080.Publisher: John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States

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An evaluation of a supratherapeutic dose of inclisiran on cardiac repolarization in healthy volunteers: A phase I, randomized study.

• Authors : Kallend D; Former Employee of The Medicines Company (Schweiz) GmbH, Zurich, Switzerland.; Mason J

Subjects: Fluoroquinolones*/Fluoroquinolones*/Fluoroquinolones*/adverse effects ; Sodium*/Sodium*/Sodium*/pharmacology; Humans

• Source: Clinical and translational science [Clin Transl Sci] 2022 Nov; Vol. 15 (11), pp. 2663-2672. Date of Electronic Publication: 2022 Oct 05.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic Cited Medium: Internet

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Short-term changes in arterial inflammation predict long-term changes in atherosclerosis progression.

• Authors : Joseph P; Cardiology Division and Cardiac MR PET CT Program, Massachusetts General Hospital and Harvard Medical School, Suite 400-165 Cambridge St, Boston, MA, 02114, USA.; Population Health Research Institute, Department of Medicine, and Department of Radiology, McMaster University, Hamilton, ON, Canada.

Subjects: Arteritis/Arteritis/Arteritis/*complications ; Arteritis/Arteritis/Arteritis/*diagnostic imaging ; Carotid Artery Diseases/Carotid Artery Diseases/Carotid Artery Diseases/*diagnostic imaging

• Source: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2017 Jan; Vol. 44 (1), pp. 141-150. Date of Electronic Publication: 2016 Oct 13.Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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The complementary roles of dynamic contrast-enhanced MRI and 18F-fluorodeoxyglucose PET/CT for imaging of carotid atherosclerosis.

• Authors : Calcagno C; Translational and Molecular Imaging Institute, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1234, New York, NY, 10029, USA.; Ramachandran S

Subjects: Contrast Media* ; Fluorodeoxyglucose F18* ; Magnetic Resonance Imaging*

• Source: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2013 Dec; Vol. 40 (12), pp. 1884-93. Date of Electronic Publication: 2013 Aug 14.Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Aldosterone does not predict cardiovascular events following acute coronary syndrome in patients initially without heart failure

Subjects: text; Journal Article

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