نتائج البحث

RORγt inverse agonist TF-S14 inhibits Th17 cytokines and prolongs skin allograft survival in sensitized mice.

• Authors : Fouda A; Division of Surgical and Interventional Sciences, Department of Surgery, McGill University, Montréal, QC, H3G 1A4, Canada. .; Research Institute of the McGill University Health Centre, Montréal, QC, H3H 2R9, Canada. .

Subjects: Cytokines* ; Drug Inverse Agonism*; Humans

• Source: Communications biology [Commun Biol] 2024 Apr 12; Vol. 7 (1), pp. 454. Date of Electronic Publication: 2024 Apr 12.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Mechano-sensitivity of β2-adrenoceptors enhances constitutive activation of cAMP generation that is inhibited by inverse agonists.

• Authors : Cullum SA; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, NG7 2UH, UK.; Centre of Membrane Proteins and Receptors, University of Nottingham, Nottingham, NG7 2UH, UK.

Subjects: Adrenergic beta-Agonists*/Adrenergic beta-Agonists*/Adrenergic beta-Agonists*/metabolism ; Adrenergic beta-Agonists*/Adrenergic beta-Agonists*/Adrenergic beta-Agonists*/pharmacology ; Drug Inverse Agonism*

• Source: Communications biology [Commun Biol] 2024 Apr 05; Vol. 7 (1), pp. 417. Date of Electronic Publication: 2024 Apr 05.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Pharmacokinetics, safety, and efficacy of cedirogant from phase I studies in healthy participants and patients with chronic plaque psoriasis.

• Authors : Mohamed MF; Clinical Pharmacology, AbbVie Inc., North Chicago, Illinois, USA.; Qian Y

Subjects: Drug Inverse Agonism* ; Psoriasis*/Psoriasis*/Psoriasis*/drug therapy; Humans

• Source: Clinical and translational science [Clin Transl Sci] 2024 Jan; Vol. 17 (1), pp. e13682. Date of Electronic Publication: 2023 Dec 19.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic Cited Medium: Internet

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Hankel and Toeplitz Determinants of Logarithmic Coefficients of Inverse Functions for the Subclass of Starlike Functions with Respect to Symmetric Conjugate Points.

• Authors : Aqilah Abdul Wahid, Nur Hazwani¹ ; Tumiran, Adawiyah¹ ; Shaba, Timilehin Gideon²

• Source: European Journal of Pure & Applied Mathematics. Jul2024, Vol. 17 Issue 3, p1818-1830. 13p.

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Co-created in vivo pharmacology practical classes using the novel organism Lumbriculus variegatus.

• Authors : Carriere JJ; Swansea Worm Integrative Research Laboratory (SWIRL), Swansea University Medical School, Swansea University, Swansea, UK.; Davies NA

Subjects: Drug Inverse Agonism* ; Learning*; Humans

• Source: Pharmacology research & perspectives [Pharmacol Res Perspect] 2023 Dec; Vol. 11 (6), pp. e01158.Publisher: John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States

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GPCR molecular dynamics forecasting using recurrent neural networks.

• Authors : López-Correa JM; Universitat Politècnica de Catalunya, Barcelona, Spain.; König C

Subjects: Molecular Dynamics Simulation* ; Drug Inverse Agonism*; Neural Networks, Computer

• Source: Scientific reports [Sci Rep] 2023 Nov 28; Vol. 13 (1), pp. 20995. Date of Electronic Publication: 2023 Nov 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Effects of (-)-MBP, a novel 5-HT 2C agonist and 5-HT 2A/2B antagonist/inverse agonist on brain activity: A phMRI study on awake mice.

• Authors : Sathe PK; Department Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts, USA.; Ramdasi GR

Subjects: Serotonin*/Serotonin*/Serotonin*/pharmacology ; Drug Inverse Agonism*; Mice

• Source: Pharmacology research & perspectives [Pharmacol Res Perspect] 2023 Oct; Vol. 11 (5), pp. e01144.Publisher: John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States

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MiRNA encoded PTEN's impact on clinical-pathological features and prognosis in osteosarcoma: A systematic review and meta-analysis.

• Authors : Limijadi, Edward Kurnia Setiawan¹ (AUTHOR); Novriansyah, Robin^2,3 (AUTHOR); Respati, Danendra Rakha Putra^3,4 (AUTHOR)

• Source: PLoS ONE. 9/19/2024, Vol. 19 Issue 9, p1-16. 16p.

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A hybrid simulation method towards the gamma ray phase contrast imaging for metallic material.

• Authors : Sun, Jiayi¹ (AUTHOR); Ding, Hao¹ (AUTHOR); Chi, Zhijun² (AUTHOR)

• Source: Scientific Reports. 9/10/2024, Vol. 14 Issue 1, p1-12. 12p.

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Cross-sectional and longitudinal analysis of health-related quality of life (HRQoL) in senior and geriatric dogs.

• Authors : Mondino, Alejandra¹ (AUTHOR); Yang, Chin-Chieh¹ (AUTHOR); Simon, Katherine E.¹ (AUTHOR)

Subjects: *VETERINARY medicine; *QUALITY of life; *INVERSE relationships (Mathematics)

• Source: PLoS ONE. 9/4/2024, Vol. 19 Issue 9, p1-15. 15p.

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