Source: BMC immunology [BMC Immunol] 2024 Oct 30; Vol. 25 (1), pp. 73. Date of Electronic Publication: 2024 Oct 30.Publisher: BioMed Central Country of Publication: England NLM ID: 100966980 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2172

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Academic Journal

The kappa/lambda ratio of surface immunoglobulin light chain as a valuable parameter for MRD assessment in CLL with atypical immunophenotype.

Authors : Aruga Y; Department of Laboratory Medicine, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.; Department of Medical Oncology and Translational Research, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.

Subjects: Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/diagnosis ; Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/pathology ; Neoplasm, Residual*/Neoplasm, Residual*/Neoplasm, Residual*/diagnosis

Source: Scientific reports [Sci Rep] 2024 Jun 11; Vol. 14 (1), pp. 13452. Date of Electronic Publication: 2024 Jun 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Biomarkers of Intrathecal Synthesis May Be Associated with Cognitive Impairment at MS Diagnosis.

Authors : Virgilio E; Neurology Unit, Department of Clinical and Biological Sciences, University Hospital San Luigi Gonzaga, University of Turin, 10043 Turin, Italy.; Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), Department of Health Sciences, University of Piemonte Orientale, 28100 Novara, Italy.

Subjects: Biomarkers*/Biomarkers*/Biomarkers*/cerebrospinal fluid ; Multiple Sclerosis*/Multiple Sclerosis*/Multiple Sclerosis*/cerebrospinal fluid ; Multiple Sclerosis*/Multiple Sclerosis*/Multiple Sclerosis*/diagnosis

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Jan 19; Vol. 26 (2). Date of Electronic Publication: 2025 Jan 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

The Increasing Role of Kappa Free Light Chains in the Diagnosis of Multiple Sclerosis.

Authors : Konen FF; Department of Neurology, Hannover Medical School, 30625 Hannover, Germany.; Schwenkenbecher P

Subjects: Immunoglobulin Light Chains/Immunoglobulin Light Chains/Immunoglobulin Light Chains/*metabolism ; Immunoglobulin kappa-Chains/Immunoglobulin kappa-Chains/Immunoglobulin kappa-Chains/*metabolism ; Multiple Sclerosis/Multiple Sclerosis/Multiple Sclerosis/*diagnosis

Source: Cells [Cells] 2021 Nov 06; Vol. 10 (11). Date of Electronic Publication: 2021 Nov 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Roles of the disulfide bond between the variable and the constant domains of rabbit immunoglobulin kappa chains in thermal stability and affinity

Authors : Toshiaki Maruyama; Raiji Kawade; C.J. Okumura

Subjects: Models, Molecular; 0301 basic medicine; Protein domain

Source: Protein Engineering, Design and Selection. 31:243-247

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Academic Journal

Silver Nanoparticles as a Tool for the Study of Spontaneous Aggregation of Immunoglobulin Monoclonal Free Light Chains.

Authors : Lizoń A; Department of Medical Diagnostics, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Cracow, Poland.; Tisończyk J

Subjects: Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*chemistry ; Immunoglobulin Light Chains/Immunoglobulin Light Chains/Immunoglobulin Light Chains/*blood ; Immunoglobulin kappa-Chains/Immunoglobulin kappa-Chains/Immunoglobulin kappa-Chains/*blood

Source: International journal of molecular sciences [Int J Mol Sci] 2021 Sep 08; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Editorial & Opinion

A rat model expressing a human amyloidogenic kappa light chain.

Authors : Ayala MV; CNRS UMR7276/INSERM U1262, University of Limoges, Limoges, France.; French National Reference Centre for AL Amyloidosis and Other Monoclonal Ig Deposition Diseases, University Hospital of Limoges and Poitiers, Limoges, France.

Subjects: Immunoglobulin Light Chains*/Immunoglobulin Light Chains*/Immunoglobulin Light Chains*/genetics ; Immunoglobulin kappa-Chains*/Immunoglobulin kappa-Chains*/Immunoglobulin kappa-Chains*/genetics; Animals

Source: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis [Amyloid] 2021 Sep; Vol. 28 (3), pp. Publisher: Taylor & Francis Country of Publication: England NLM ID: 9433802 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Kappa Free Light Chains in the Context of Blood Contamination, and Other IgA- and IgM-Related Cerebrospinal Fluid Disease Pattern.

Authors : Hannich MJ; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.; Dressel A

Subjects: Immunoglobulin A*/Immunoglobulin A*/Immunoglobulin A*/biosynthesis ; Immunoglobulin A*/Immunoglobulin A*/Immunoglobulin A*/blood ; Immunoglobulin A*/Immunoglobulin A*/Immunoglobulin A*/cerebrospinal fluid

Source: Cells [Cells] 2021 Mar 11; Vol. 10 (3). Date of Electronic Publication: 2021 Mar 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Generation of a mouse strain that produces immunoglobulin kappa chains with human constant regions.

Authors : Zou YR; Institute for Genetics, University of Cologne, Germany.; Gu H

Subjects: Genes, Immunoglobulin*; B-Lymphocytes/B-Lymphocytes/B-Lymphocytes/*immunology ; Immunoglobulin Constant Regions/Immunoglobulin Constant Regions/Immunoglobulin Constant Regions/*biosynthesis

Source: Science (New York, N.Y.) [Science] 1993 Nov 19; Vol. 262 (5137), pp. 1271-4.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium:

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Impact of M-protein detection on the response evaluations of patients undergoing treatment with the IgG-κ monoclonal antibodies daratumumab or isatuximab, and discrepancies between immunofixation electrophoresis (IFE) systems and reagents.

Authors : Shirouchi Y; Department of Hematology Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.; Kaihara K

Subjects: Antibodies, Monoclonal*/Antibodies, Monoclonal*/Antibodies, Monoclonal*/therapeutic use ; Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/drug therapy ; Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/blood

Source: Cancer medicine [Cancer Med] 2024 Aug; Vol. 13 (16), pp. e70128.Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print Cited Medium: Internet ISSN:

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نتائج البحث

فلترة النتائج

Warning values of serum total kappa/lambda ratio for M-proteinemia.

The kappa/lambda ratio of surface immunoglobulin light chain as a valuable parameter for MRD assessment in CLL with atypical immunophenotype.

Biomarkers of Intrathecal Synthesis May Be Associated with Cognitive Impairment at MS Diagnosis.

The Increasing Role of Kappa Free Light Chains in the Diagnosis of Multiple Sclerosis.

Roles of the disulfide bond between the variable and the constant domains of rabbit immunoglobulin kappa chains in thermal stability and affinity

Silver Nanoparticles as a Tool for the Study of Spontaneous Aggregation of Immunoglobulin Monoclonal Free Light Chains.

A rat model expressing a human amyloidogenic kappa light chain.

Kappa Free Light Chains in the Context of Blood Contamination, and Other IgA- and IgM-Related Cerebrospinal Fluid Disease Pattern.

Generation of a mouse strain that produces immunoglobulin kappa chains with human constant regions.

Impact of M-protein detection on the response evaluations of patients undergoing treatment with the IgG-κ monoclonal antibodies daratumumab or isatuximab, and discrepancies between immunofixation electrophoresis (IFE) systems and reagents.

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