Source: Scientific reports [Sci Rep] 2025 Jan 25; Vol. 15 (1), pp. 3250. Date of Electronic Publication: 2025 Jan 25.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

HIF-1α-HPRT1 axis promotes tumorigenesis and gefitinib resistance by enhancing purine metabolism in EGFR-mutant lung adenocarcinoma.

Authors : Geng P; State Key Laboratory of Medical Proteomics, CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning Province, 116023, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian, Liaoning Province, 116023, China.

Subjects: ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/metabolism ; ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/genetics ; Gefitinib*/Gefitinib*/Gefitinib*/pharmacology

Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Sep 30; Vol. 43 (1), pp. 269. Date of Electronic Publication: 2024 Sep 30.Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Perfecting a high hypoxanthine phosphoribosyltransferase activity-uricase KO mice to test the effects of purine- and non-purine-type xanthine dehydrogenase (XDH) inhibitors.

Authors : Hosoya T; Department of Human Physiology & Pathology, Faculty of Pharma-Science, Teikyo University, Tokyo, Japan.; Biological Research Department, Medical R&D Division, Fuji Yakuhin Co., Ltd., Saitama, Japan.

Subjects: Urate Oxidase*; Animals ; Mice

Source: British journal of pharmacology [Br J Pharmacol] 2020 May; Vol. 177 (10), pp. 2274-2285. Date of Electronic Publication: 2020 Feb 18.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Toxicological investigation of lilial.

Authors : Jablonská E; Department of Biochemistry and Microbiology, University of Chemistry and Technology, Prague, Technická 5, 166 28, Prague 6, Czech Republic.; Míchal Z

Subjects: Hypoxanthine Phosphoribosyltransferase* ; NF-kappa B*; Humans

Source: Scientific reports [Sci Rep] 2023 Oct 28; Vol. 13 (1), pp. 18536. Date of Electronic Publication: 2023 Oct 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Helicobacter pylori Xanthine-Guanine-Hypoxanthine Phosphoribosyltransferase-A Putative Target for Drug Discovery against Gastrointestinal Tract Infections

Authors : Keough, Dianne T.; Wun, Shun Jie; Baszczynski, Ondrej

Subjects: Science & Technology; Life Sciences & Biomedicine; Chemistry

Source: ISSN:0022-2623 ; ISSN:1520-4804 ; Journal Of Medicinal Chemistry, vol. 64 (9), (5710-5729.

تفاصيل العنوان

اقرأ أكثر حفظ في قائمتي

Academic Journal

Identification of Optimal Reference Genes for qRT-PCR Normalization for Physical Activity Intervention and Omega-3 Fatty Acids Supplementation in Humans.

Authors : Grzybkowska A; Faculty of Physical Education, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.; Anczykowska K

Subjects: Hypoxanthine Phosphoribosyltransferase*/Hypoxanthine Phosphoribosyltransferase*/Hypoxanthine Phosphoribosyltransferase*/genetics ; Fatty Acids, Omega-3*; Male

Source: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 04; Vol. 24 (7). Date of Electronic Publication: 2023 Apr 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Bioactivation, Mutagenicity, DNA Damage, and Oxidative Stress Induced by 3,4-Dimethylaniline.

Authors : Habil MR; Department of Pharmacology & Toxicology, University of Louisville School of Medicine, Louisville, KY 40202, USA.; Salazar-González RA

Subjects: Cricetulus* ; Oxidative Stress*/Oxidative Stress*/Oxidative Stress*/drug effects ; Aniline Compounds*/Aniline Compounds*/Aniline Compounds*/toxicity

Source: Biomolecules [Biomolecules] 2024 Dec 07; Vol. 14 (12). Date of Electronic Publication: 2024 Dec 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

The role for glutamic acid at position 196 in human hypoxanthine phosphoribosyltransferase (HPRT) as investigated using site-directed mutagenesis.

Authors : Canyuk B; Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Science, Prince of Songkla University, Songkhla, Thailand. ; E-Wan A

Subjects: Mutagenesis, Site-Directed*; Glutamic Acid/Glutamic Acid/Glutamic Acid/*metabolism ; Hypoxanthine Phosphoribosyltransferase/Hypoxanthine Phosphoribosyltransferase/Hypoxanthine Phosphoribosyltransferase/*genetics

Source: Nucleosides, nucleotides & nucleic acids [Nucleosides Nucleotides Nucleic Acids] 2008 Jun; Vol. 27 (6), pp. 894-9.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 100892832 Publication Model: Print Cited Medium: Internet ISSN:

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Abundance, efficiency, and stability of reference transcript expression in a seasonal rodent: The Siberian hamster.

Authors : Stewart C; School of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow, United Kingdom.; Liddle TA

Subjects: Hypoxanthine Phosphoribosyltransferase* ; Phodopus*/Phodopus*/Phodopus*/genetics; Actins

Source: PloS one [PLoS One] 2022 Oct 03; Vol. 17 (10), pp. e0275263. Date of Electronic Publication: 2022 Oct 03 (Print Publication: 2022).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Efficacy and safety of allopurinol in patients with the Lesch-Nyhan syndrome and partial hypoxanthine- phosphoribosyltransferase deficiency: a follow-up study of 18 Spanish patients.

Authors : Torres RJ; Biochemistry Laboratory, La Paz University Hospital, Madrid, Spain.; Prior C

Subjects: Allopurinol/Allopurinol/Allopurinol/*therapeutic use ; Hypoxanthine Phosphoribosyltransferase/Hypoxanthine Phosphoribosyltransferase/Hypoxanthine Phosphoribosyltransferase/*deficiency ; Lesch-Nyhan Syndrome/Lesch-Nyhan Syndrome/Lesch-Nyhan Syndrome/*drug therapy

Source: Nucleosides, nucleotides & nucleic acids [Nucleosides Nucleotides Nucleic Acids] 2006; Vol. 25 (9-11), pp. 1077-82.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 100892832 Publication Model: Print Cited Medium: Print ISSN: 1525-7770

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

نتائج البحث

فلترة النتائج

Pseudogenization of the Slc23a4 gene is necessary for the survival of Xdh-deficient mice.

HIF-1α-HPRT1 axis promotes tumorigenesis and gefitinib resistance by enhancing purine metabolism in EGFR-mutant lung adenocarcinoma.

Perfecting a high hypoxanthine phosphoribosyltransferase activity-uricase KO mice to test the effects of purine- and non-purine-type xanthine dehydrogenase (XDH) inhibitors.

Toxicological investigation of lilial.

Helicobacter pylori Xanthine-Guanine-Hypoxanthine Phosphoribosyltransferase-A Putative Target for Drug Discovery against Gastrointestinal Tract Infections

Identification of Optimal Reference Genes for qRT-PCR Normalization for Physical Activity Intervention and Omega-3 Fatty Acids Supplementation in Humans.

Bioactivation, Mutagenicity, DNA Damage, and Oxidative Stress Induced by 3,4-Dimethylaniline.

The role for glutamic acid at position 196 in human hypoxanthine phosphoribosyltransferase (HPRT) as investigated using site-directed mutagenesis.

Abundance, efficiency, and stability of reference transcript expression in a seasonal rodent: The Siberian hamster.

Efficacy and safety of allopurinol in patients with the Lesch-Nyhan syndrome and partial hypoxanthine- phosphoribosyltransferase deficiency: a follow-up study of 18 Spanish patients.

اتصل بنا

اتبع