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Quisinostat is a brain-penetrant radiosensitizer in glioblastoma

• Authors : Lo Cascio, Costanza; Margaryan, Tigran; Luna-Melendez, Ernesto

Subjects: Brain cancer; Drug therapy; Oncology

• Source: Translational Neuroscience

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An innovative automated active compound screening system allows high-throughput optimization of somatic embryogenesis in Coffea arabica

• Authors : Awada, Rayan; Verdier, Dorothée; Froger, Solène ...

Subjects: Somatic embryogenesis; Coffee; High throughput optimization

• Source: ISSN: 2045-2322.

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Histone deacetylase inhibitors promote the tumoricidal effect of HAMLET.

• Authors : Brest, Patrick; Gustafsson, Mattias; Mossberg, Anki

Subjects: Histone Deacetylases: metabolism; Histones: metabolism; Histone Deacetylases: antagonists & inhibitors

• Source: Cancer Research. 67(23):11327-11334

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A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing

• Authors : Simoben, Conrad; Robaa, Dina; Chakrabarti, Alokta ...

Subjects: crystal structure; docking; epigenetics

• Source: ISSN: 1420-3049 ; Molecules ; https://hal.science/hal-02391176 ; Molecules, 2018, 23 (3), pp.566. ⟨10.3390/molecules23030566⟩.

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HDAC inhibition in the cpfl1 mouse protects degenerating cone photoreceptors in vivo

• Authors : Trifunović, Dragana; Arango-Gonzalez, Blanca; Comitato, Antonella

Subjects: Animals; Disease Models; Animal

• Source: Trifunović , D , Arango-Gonzalez , B , Comitato , A , Barth , M , Del Amo , E M , Kulkarni , M , Sahaboglu , A , Hauck , S M , Urtti , A , Arsenijevic , Y , Ueffing , M , Marigo , V & Paquet-Durand ,

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Epigenetic Library Screen Identifies Abexinostat as Novel Regulator of Adipocytic and Osteoblastic Differentiation of Human Skeletal (Mesenchymal) Stem Cells

• Authors : Ali, D.; Hamam, R.; Alfayez, M.

Subjects: Adipocyte; Epigenetic; Histone deacetylase inhibitors

• Source: Ali , D , Hamam , R , Alfayez , M , Kassem , M , Aldahmash , A & Alajez , N M 2016 , ' Epigenetic Library Screen Identifies Abexinostat as Novel Regulator of Adipocytic and Osteoblastic

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Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice

• Authors : Déprez-Poulain, Rebecca; Hennuyer, Nathalie; Bosc, Damien ...

Subjects: MESH: Animals; MESH: Caco-2 Cells; MESH: Hydroxamic Acids/chemical synthesis

• Source: ISSN: 2041-1723.

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Potential anti-cancer effect of N-hydroxy-7-(2-naphthylthio) heptanomide (HNHA), a novel histone deacetylase inhibitor, for the treatment of thyroid cancer.

• Authors : College of Medicine; Dept. of Surgery; Seok-Mo Kim

Subjects: Apoptosis/drug effects; Calcium/metabolism; Caspases/metabolism

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Inhibition of histone deacetylases enhances the function of serotoninergic neurons in organotypic raphe slice cultures.

• Authors : Asaoka, Nozomi; Nagayasu, Kazuki; Nishitani, Naoya ...

Subjects: Histone deacetylase; Serotonin; Raphe slice cultures

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A new histone deacetylase inhibitor improves liver fibrosis in BDL rats through suppression of hepatic stellate cells

• Authors : Ki Cheong Park; Ji Hyun Park; Jeong Yong Jeon

Subjects: Actins/metabolism; Animals; Bile Ducts/surgery

• Source: T201403823.pdf

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