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  • 1-10 ل  16,532 نتائج ل ""Huntington Disease""

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Academic Journal

Age- and disease-related autophagy impairment in Huntington disease: New insights from direct neuronal reprogramming.

  • Authors : Luo C; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, China.; Yang J

Subjects: Huntington Disease*/Huntington Disease*/Huntington Disease*/pathology ; Huntington Disease*/Huntington Disease*/Huntington Disease*/metabolism ; Huntington Disease*/Huntington Disease*/Huntington Disease*/genetics

  • Source: Aging cell [Aging Cell] 2024 Aug; Vol. 23 (8), pp. e14285. Date of Electronic Publication: 2024 Jul 23.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mapping the glial transcriptome in Huntington's disease using snRNAseq: selective disruption of glial signatures across brain regions.

  • Authors : Bøstrand SMK; Centre for Regenerative Medicine, Institute of Regeneration and Repair, University of Edinburgh, Edinburgh, UK.; Seeker LA

Subjects: Huntington Disease*/Huntington Disease*/Huntington Disease*/genetics ; Huntington Disease*/Huntington Disease*/Huntington Disease*/pathology ; Huntington Disease*/Huntington Disease*/Huntington Disease*/metabolism

  • Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Oct 21; Vol. 12 (1), pp. 165. Date of Electronic Publication: 2024 Oct 21.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960

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Academic Journal

Elevated plasma and CSF neurofilament light chain concentrations are stabilized in response to mutant huntingtin lowering in the brains of Huntington's disease mice.

  • Authors : Caron NS; Centre for Molecular Medicine and Therapeutics, Vancouver, BC, V5Z 4H4, Canada.; BC Children's Hospital Research Institute, Vancouver, BC, V5Z 4H4, Canada.

Subjects: Huntington Disease*/Huntington Disease*/Huntington Disease*/genetics ; Huntington Disease*/Huntington Disease*/Huntington Disease*/blood ; Huntington Disease*/Huntington Disease*/Huntington Disease*/cerebrospinal fluid

  • Source: Translational neurodegeneration [Transl Neurodegener] 2024 Oct 08; Vol. 13 (1), pp. 50. Date of Electronic Publication: 2024 Oct 08.Publisher: BioMed Central Country of Publication: England NLM ID: 101591861 Publication Model: Electronic Cited Medium: Print ISSN: 2047-9158

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Academic Journal

Two novel DnaJ chaperone proteins CG5001 and P58IPK regulate the pathogenicity of Huntington's disease related aggregates.

  • Authors : Deo A; Department of Biotechnology, Savitribai Phule Pune University, Ganeshkhind, Pune, 411007, India.; Ghosh R

Subjects: Drosophila Proteins*/Drosophila Proteins*/Drosophila Proteins*/metabolism ; Drosophila Proteins*/Drosophila Proteins*/Drosophila Proteins*/genetics ; HSP40 Heat-Shock Proteins*/HSP40 Heat-Shock Proteins*/HSP40 Heat-Shock Proteins*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Sep 06; Vol. 14 (1), pp. 20867. Date of Electronic Publication: 2024 Sep 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Luteolin as potential treatment for Huntington's disease: Insights from a transgenic mouse model.

  • Authors : Mohammed A; Department of Basic Medical Sciences, College of Medicine-Dar Al Uloom University, Riyadh, Saudi Arabia.; Department of Histology and Embryology, School of Basic Medical Sciences, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Subjects: Huntington Disease*/Huntington Disease*/Huntington Disease*/drug therapy ; Huntington Disease*/Huntington Disease*/Huntington Disease*/metabolism ; Luteolin*/Luteolin*/Luteolin*/pharmacology

  • Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Sep; Vol. 30 (9), pp. e70025.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949

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Academic Journal

Peripheral sequestration of huntingtin delays neuronal death and depends on N-terminal ubiquitination.

  • Authors : Boulos A; Technion Faculty of Medicine, Rappaport Institute and Network Biology Research Laboratories, Fishbach Building, Technion City, Haifa, Israel.; Department of Neurology, Massachusetts General Hospital, and Harvard Medical School, Charlestown, MA, USA.

Subjects: Huntingtin Protein*/Huntingtin Protein*/Huntingtin Protein*/genetics ; Huntingtin Protein*/Huntingtin Protein*/Huntingtin Protein*/metabolism ; Ubiquitination*

  • Source: Communications biology [Commun Biol] 2024 Aug 18; Vol. 7 (1), pp. 1014. Date of Electronic Publication: 2024 Aug 18.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Leveraging explainable deep learning methodologies to elucidate the biological underpinnings of Huntington's disease using single-cell RNA sequencing data.

  • Authors : Gao S; School of Life Sciences, Anhui University, Hefei, 230601, China.; College of Biology and Food Engineering, Chuzhou University, Chuzhou, 239000, China.

Subjects: Huntington Disease*/Huntington Disease*/Huntington Disease*/genetics ; Deep Learning* ; Single-Cell Analysis*/Single-Cell Analysis*/Single-Cell Analysis*/methods

  • Source: BMC genomics [BMC Genomics] 2024 Oct 04; Vol. 25 (1), pp. 930. Date of Electronic Publication: 2024 Oct 04.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164

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Academic Journal

Deep behavioural phenotyping of the Q175 Huntington disease mouse model: effects of age, sex, and weight.

  • Authors : Koch ET; Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, Vancouver, BC, Canada. .; Present Address: Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, AB, T2N 2T9, Canada. .

Subjects: Huntington Disease*/Huntington Disease*/Huntington Disease*/physiopathology ; Huntington Disease*/Huntington Disease*/Huntington Disease*/genetics ; Disease Models, Animal*

  • Source: BMC biology [BMC Biol] 2024 May 23; Vol. 22 (1), pp. 121. Date of Electronic Publication: 2024 May 23.Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007

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Academic Journal

6-shogaol against 3-Nitropropionic acid-induced Huntington's disease in rodents: Based on molecular docking/targeting pro-inflammatory cytokines/NF-κB-BDNF-Nrf2 pathway.

  • Authors : Jambi EJ; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.

Subjects: Huntington Disease*/Huntington Disease*/Huntington Disease*/metabolism ; Huntington Disease*/Huntington Disease*/Huntington Disease*/chemically induced ; Huntington Disease*/Huntington Disease*/Huntington Disease*/drug therapy

  • Source: PloS one [PLoS One] 2024 Jul 15; Vol. 19 (7), pp. e0305358. Date of Electronic Publication: 2024 Jul 15 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Heavy Metal Interactions with Neuroglia and Gut Microbiota: Implications for Huntington's Disease.

  • Authors : Tizabi Y; Department of Pharmacology, Howard University College of Medicine, Washington, DC 20059, USA.; Bennani S

Subjects: Huntington Disease*/Huntington Disease*/Huntington Disease*/microbiology ; Huntington Disease*/Huntington Disease*/Huntington Disease*/metabolism ; Huntington Disease*/Huntington Disease*/Huntington Disease*/pathology

  • Source: Cells [Cells] 2024 Jul 03; Vol. 13 (13). Date of Electronic Publication: 2024 Jul 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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  • 1-10 ل  16,532 نتائج ل ""Huntington Disease""