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ACMSD inhibition corrects fibrosis, inflammation, and DNA damage in MASLD/MASH.

• Authors : Liu, Y.J.; Kimura, M.; Li, X.

Subjects: Animals; Mice; Humans

• Source: Journal of hepatology, vol. 82, no. 2, pp. 174-188

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In Vitro Hepatic Metabolism Input Parameters Support Toxicokinetic Simulations for the Formation of Methoxy Propionic Acid From β-Isomer Propylene Glycol Methyl Ether.

• Authors : Werner, S.; Hegg, L.; Hopf, N.B.

Subjects: Humans; Propionates/chemistry; Propionates/metabolism

• Source: Pharmacology research & perspectives, vol. 12, no. 6, pp. e70037

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Severe homocysteinemia in two givosiran-treated porphyria patients: is free heme deficiency the culprit?

• Authors : petrides, petro; Klein, Michael; Schuhmann, Elfriede

Subjects: Heme/therapeutic use [MeSH]; Hyperhomocysteinemia/etiology [MeSH]; Porphyria

• Source: http://lobid.org/resources/99370678538206441#!, 100(7):1685-1693.

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Novel FoxO1 inhibitor, JY-2, ameliorates palmitic acid-induced lipotoxicity and gluconeogenesis in a murine model

• Authors : Hye-Eun Choi; YuSik Kim; Han-Joo Lee

Subjects: Animals; Blood Glucose / drug effects; Blood Glucose / metabolism

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Clinical stage drugs targeting inhibitor of apoptosis proteins purge episomal Hepatitis B viral genome in preclinical models

• Authors : Michelle P Clark; Thao Huynh; Shringar Rao

Subjects: Animals; Antiviral Agents / pharmacology; Azocines / pharmacology

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Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver

• Authors : Lin, Heng; Huang, Yen-Sung; Fustin, Jean-Michel

Subjects: Animals; Carcinoma; Hepatocellular/chemically induced

• Source: Lin , H , Huang , Y-S , Fustin , J-M , Doi , M , Chen , H , Lai , H-H , Lin , S-H , King , P-C , Hou , H-S , Chen , H-W , Young , P-Y & Chao , H-W 2021 , ' Hyperpolyploidization of hepatocyte

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Long Non-Coding RNAs Involved in Progression of Non-Alcoholic Fatty Liver Disease to Steatohepatitis

• Authors : Atanasovska, Biljana; Rensen, Sander S.; Marsman, Glenn

Subjects: Case-Control Studies; Disease Progression; Fatty Acids

• Source: Atanasovska , B , Rensen , S S , Marsman , G , Shiri-Sverdlov , R , Withoff , S , Kuipers , F , Wijmenga , C , van de Sluis , B & Fu , J 2021 , ' Long Non-Coding RNAs Involved in Progression of

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Steatosis Alters the Activity of Hepatocyte Membrane Transporters in Obese Rats

• Authors : Pastor, Catherine; Vilgrain, Valérie

Subjects: info:eu-repo/classification/ddc/616.0757; Hepatocyte concentrations; Hepatocyte membrane transporter

• Source: ISSN: 2073-4409 ; Cells, vol. 10, no. 10 (2021) 2733.

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In vitro prediction of organ toxicity: the challenges of scaling and secondary mechanisms of toxicity

• Authors : Hengstler, Jan G.; Sjögren, Anna-Karin; Zink, Daniele

Subjects: Dose-Response Relationship; Drug [MeSH]; Pharmacology/Toxicology

• Source: http://lobid.org/resources/99370671250806441#!, 94(2):353-356.

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A Modified Protocol of Diethylnitrosamine Administration in Mice to Model Hepatocellular Carcinoma

• Authors : Azra Memon; Yuliya Pyao; Yerin Jung

Subjects: Animals; Carcinoma; Hepatocellular / drug therapy

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