نتائج البحث

Analysis of raltegravir analogs to enhance inhibitory efficiency against HIV integrase

• Authors : Hanieh Sabaghian; Mehdi Yoosefian

Subjects: HIV-1 integrase; Drug design; Viral disease treatment

• Source: Scientific Reports, Vol 15, Iss 1, Pp 1-15 (2025)

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Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential

• Authors : Slavish, Peter J; Cuypers, Maxime G; Rimmer, Mary Ashley

Subjects: Medical Microbiology; Biomedical and Clinical Sciences; Antimicrobial Resistance

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Development and Optimization of Oligonucleotide Ligation Assay (OLA) Probes for Detection of HIV-1 Resistance to Dolutegravir.

• Authors : Beck IA; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.; Boyce CL

Subjects: Oxazines* ; HIV-1*/HIV-1*/HIV-1*/genetics ; HIV-1*/HIV-1*/HIV-1*/drug effects

• Source: Viruses [Viruses] 2024 Jul 19; Vol. 16 (7). Date of Electronic Publication: 2024 Jul 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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TAR RNA Mimicry of INI1 and Its Influence on Non-Integration Function of HIV-1 Integrase.

• Authors : Kalpana GV; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.; Ernst E

Subjects: HIV-1*/HIV-1*/HIV-1*/physiology ; HIV-1*/HIV-1*/HIV-1*/genetics ; HIV-1*/HIV-1*/HIV-1*/enzymology

• Source: Viruses [Viruses] 2025 May 11; Vol. 17 (5). Date of Electronic Publication: 2025 May 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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Effectiveness of dolutegravir-based treatment among HIV/AIDS patients in Nkembo Outpatient Treatment Center, Gabon.

• Authors : Mangala, Christian¹ (AUTHOR) ; Moukanda-Ifoundou, Rolf² (AUTHOR); Maulot-Bangola, Denis^1,3 (AUTHOR)

• Source: AIDS Research & Therapy. 5/3/2025, Vol. 22 Issue 1, p1-5. 5p.

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No transmitted drug resistance to HIV integrase strand-transfer inhibitors after their scale-up in Estonia in 2017

• Authors : Arina Šablinskaja; Merit Pauskar; Ene-Ly Jõgeda

Subjects: Estonia; Integrase strand transfer inhibitor; HIV-transmitted drug resistance

• Source: Journal of Global Antimicrobial Resistance, Vol 33, Iss, Pp 83-88 (2023)

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A clinical review of HIV integrase strand transfer inhibitors (INSTIs) for the prevention and treatment of HIV-1 infection.

• Authors : Zhao AV; Department of Pharmacy Practice and Translational Research, University of Houston, 4849 Calhoun Road Rm 3044, Houston, TX, 77204-5039, USA. .; Crutchley RD

Subjects: HIV Infections*/HIV Infections*/HIV Infections*/drug therapy ; HIV Infections*/HIV Infections*/HIV Infections*/prevention & control ; HIV Integrase*/HIV Integrase*/HIV Integrase*/genetics

• Source: Retrovirology [Retrovirology] 2022 Oct 22; Vol. 19 (1), pp. 22. Date of Electronic Publication: 2022 Oct 22.Publisher: BioMed Central Country of Publication: England NLM ID: 101216893 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-4690

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ROS-mediated damage to the core domain of HIV integrase: A molecular dynamics simulation

• Authors : Cunjia Pan; Qiaoyue Chen; Danfeng Liu

Subjects: Physics; QC1-999

• Source: AIP Advances, Vol 14, Iss 10, Pp 105314-105314-7 (2024)

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Inhibition of Adipose Tissue Beiging by HIV Integrase Inhibitors, Dolutegravir and Bictegravir, Is Associated with Adipocyte Hypertrophy, Hypoxia, Elevated Fibrosis, and Insulin Resistance in Simian Adipose Tissue and Human Adipocytes.

• Authors : Ngono Ayissi, Kenza¹ (AUTHOR) ; Gorwood, Jennifer¹ (AUTHOR) ; Le Pelletier, Laura¹ (AUTHOR)

• Source: Cells (2073-4409). Jun2022, Vol. 11 Issue 11, p1841-1841. 16p.

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First Reported Case of Integrase Strand Transfer Inhibitor Resistance in Suriname: Unusual Drug Resistance Mutations Following Exposure to Dolutegravir.

• Authors : Sno RC; 'Prof. Dr. Paul C. Flu' Institute for Biomedical Sciences, Kernkampweg 5, Paramaribo, Suriname.; Culbard G

Subjects: Drug Resistance, Viral*/Drug Resistance, Viral*/Drug Resistance, Viral*/genetics ; Heterocyclic Compounds, 3-Ring*/Heterocyclic Compounds, 3-Ring*/Heterocyclic Compounds, 3-Ring*/therapeutic use ; Heterocyclic Compounds, 3-Ring*/Heterocyclic Compounds, 3-Ring*/Heterocyclic Compounds, 3-Ring*/pharmacology

• Source: Viruses [Viruses] 2025 Feb 11; Vol. 17 (2). Date of Electronic Publication: 2025 Feb 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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