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Identification of Potential Inhibitors of Histone Deacetylase 6 Through Virtual Screening and Molecular Dynamics Simulation Approach: Implications in Neurodegenerative Diseases.

• Authors : Shamsi, Anas¹ (AUTHOR) ; Shahwan, Moyad^1,2 (AUTHOR); Zuberi, Azna³ (AUTHOR)

• Source: Pharmaceuticals (14248247). Nov2024, Vol. 17 Issue 11, p1536. 18p.

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[The effect of c-Myc on regulating the immune-related ligands in Y subtype small cell lung cancer through histone deacetylase 1].

• Authors : Zhao PY; Postdoctoral Research Workstation, Jilin Cancer Hospital, Changchun130012, China Translational Oncology Research Lab, Jilin Cancer Hospital, Changchun130012, China.; Sun XD

Subjects: Histone Deacetylase 1*/Histone Deacetylase 1*/Histone Deacetylase 1*/metabolism ; Small Cell Lung Carcinoma*/Small Cell Lung Carcinoma*/Small Cell Lung Carcinoma*/metabolism ; Small Cell Lung Carcinoma*/Small Cell Lung Carcinoma*/Small Cell Lung Carcinoma*/pathology

• Source: Zhonghua zhong liu za zhi [Chinese journal of oncology] [Zhonghua Zhong Liu Za Zhi] 2024 Nov 23; Vol. 46 (11), pp. 1009-1018.Publisher: Chinese Medical Association Country of Publication: China NLM ID: 7910681 Publication Model: Print Cited Medium: Print ISSN: 0253-3766

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Drug repositioning identifies histone deacetylase inhibitors that promote innate immunity in non-tuberculous mycobacterial infection.

• Authors : Rodriguez-Carlos, Adrián¹ (AUTHOR); Raúl, Anguita² (AUTHOR); Jacobo-Delgado, Yolanda M.¹ (AUTHOR)

Subjects: *MYCOBACTERIAL diseases; *HISTONE deacetylase inhibitors; *NATURAL immunity

• Source: Canadian Journal of Microbiology. 2024, Vol. 70 Issue 7, p252-261. 10p.

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Evaluation of Serum Level of Histone Deacetylase 1 Enzyme in Patients with Acne Vulgaris.

• Authors : Bahloul, Rania M.¹ ; Abdelgaber, Soheir¹; El Arman, Mohammed M.²

Subjects: *ACNE; *HISTONE deacetylase; *HISTONE acetylation

• Source: Egyptian Journal of Hospital Medicine. Jul2024, Vol. 96, p3169-3173. 5p.

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Molecular docking, ADMET, molecular dynamic simulation, synthesis, and preliminary antiproliferative study of 1,2,4-thiadiazole derivatives as possible histone deacetylase inhibitors.

• Authors : Ali, Rusul Mohammed Hasan¹; Al-Hamashi, Ayad A.¹

• Source: Tropical Journal of Pharmaceutical Research. Jul2024, Vol. 23 Issue 7, p1069-1076. 8p.

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Inhibiting histone deacetylase 6 suppresses the proliferation of microvascular endothelial cells by epigenetically activating miR-375-3p, potentially contributing to bone loss during mechanical unloading.

• Authors : Xu L; The Key Laboratory of Aerospace Medicine, Ministry of Education, Air Force Medical University, Xi'an, Shaanxi, 710032, China.; Zhang L

Subjects: MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism ; MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics ; Cell Proliferation*

• Source: Journal of translational medicine [J Transl Med] 2024 Sep 02; Vol. 22 (1), pp. 811. Date of Electronic Publication: 2024 Sep 02.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Histone deacetylase 7 activates 6-phosphogluconate dehydrogenase via an enzyme-independent mechanism that involves the N-terminal protein-protein interaction domain.

• Authors : Yizhuo Wang^1,2; Curson, James E. B.^1,2; Ramnath, Divya^1,2

Subjects: *PENTOSE phosphate pathway; *HISTONE deacetylase; *PROTEIN-protein interactions

• Source: Biochemical Journal. Nov2024, Vol. 481 Issue 21, p1569-1584. 16p.

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Fermented Wheat Germ Protein with Histone Deacetylase Inhibitor AR42 Demonstrates Enhanced Cytotoxicity against Lymphoma Cells In Vitro and In Vivo.

• Authors : Meckler, Joshua F.¹ (AUTHOR) ; Levis, Daniel J.¹ (AUTHOR) ; Kong, Yanguo¹ (AUTHOR)

Subjects: *WHEAT germ; *HISTONE deacetylase inhibitors; *WHEAT proteins

• Source: International Journal of Molecular Sciences. Jul2024, Vol. 25 Issue 14, p7866. 12p.

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Therapeutic role of histone deacetylase inhibition in an in vitro model of Graves' orbitopathy.

• Authors : Byeon HJ; Department of Ophthalmology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Republic of Korea.; Choi SH

Subjects: Graves Ophthalmopathy*/Graves Ophthalmopathy*/Graves Ophthalmopathy*/metabolism ; Graves Ophthalmopathy*/Graves Ophthalmopathy*/Graves Ophthalmopathy*/drug therapy ; Graves Ophthalmopathy*/Graves Ophthalmopathy*/Graves Ophthalmopathy*/genetics

• Source: Molecular medicine reports [Mol Med Rep] 2024 Dec; Vol. 30 (6). Date of Electronic Publication: 2024 Sep 27.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Histone deacetylase 6 as a novel promising target to treat cardiovascular disease.

• Authors : Wu, Ya‐Xi¹ (AUTHOR); Li, Bing‐Qian¹ (AUTHOR); Yu, Xiao‐Qian¹ (AUTHOR)

• Source: Cancer Innovation. Jun2024, Vol. 3 Issue 3, p1-15. 15p.

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