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  • 1-10 ل  979 نتائج ل ""Genes, Lethal""

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Academic Journal

Systematic analysis of cancer-specific synthetic lethal interactions provides insight into personalized anticancer therapy.

  • Authors : Guo L; Department of Bioinformatics, Smart Health Big Data Analysis and Location Services Engineering Lab of Jiangsu Province, School of Geographic and Biologic Information, Nanjing University of Posts and Telecommunications, China.; Dou Y

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Genes, Lethal*/Genes, Lethal*/Genes, Lethal*/genetics

  • Source: The FEBS journal [FEBS J] 2023 Mar; Vol. 290 (6), pp. 1531-1548. Date of Electronic Publication: 2022 Oct 17.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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Academic Journal

Mendelian gene identification through mouse embryo viability screening.

Subjects: Embryo, Mammalian* ; Genes, Lethal*; Animals

  • Source: Genome medicine [Genome Med] 2022 Oct 13; Vol. 14 (1), pp. 119. Date of Electronic Publication: 2022 Oct 13.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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Academic Journal

Long range segmentation of prokaryotic genomes by gene age and functionality.

  • Authors : Wolf YI; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.; Schurov IV

Subjects: Genome, Archaeal* ; Evolution, Molecular* ; Genome, Bacterial*

  • Source: Nucleic acids research [Nucleic Acids Res] 2024 Oct 14; Vol. 52 (18), pp. 11045-11059.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Population suppression with dominant female-lethal alleles is boosted by homing gene drive.

  • Authors : Zhu J; Center for Bioinformatics, Center for Life Sciences, School of Life Sciences, Peking University, Beijing, 100871, China.; Chen J

Subjects: Gene Drive Technology*/Gene Drive Technology*/Gene Drive Technology*/methods ; Drosophila melanogaster*/Drosophila melanogaster*/Drosophila melanogaster*/genetics ; Alleles*

  • Source: BMC biology [BMC Biol] 2024 Sep 11; Vol. 22 (1), pp. 201. Date of Electronic Publication: 2024 Sep 11.Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007

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Academic Journal

Holocarboxylase synthetase knockout is embryonic lethal in mice.

  • Authors : Sadri M; Department of Nutrition and Health Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, United States of America.; Wang H

Subjects: Carbon-Nitrogen Ligases*/Carbon-Nitrogen Ligases*/Carbon-Nitrogen Ligases*/genetics ; Carbon-Nitrogen Ligases*/Carbon-Nitrogen Ligases*/Carbon-Nitrogen Ligases*/metabolism ; Genes, Lethal*

  • Source: PloS one [PLoS One] 2022 Apr 06; Vol. 17 (4), pp. e0265539. Date of Electronic Publication: 2022 Apr 06 (Print Publication: 2022).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Broad spectrum of CRISPR-induced edits in an embryonic lethal gene.

  • Authors : Fuselier KTB; Department of Developmental Biology, Pennington Biomedical Research Center/Louisiana State University System, 6400 Perkins Road, Baton Rouge, LA, 70808, USA.; Salbaum JM

Subjects: CRISPR-Cas Systems* ; Gene Editing* ; Genes, Lethal*

  • Source: Scientific reports [Sci Rep] 2021 Dec 09; Vol. 11 (1), pp. 23732. Date of Electronic Publication: 2021 Dec 09.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Weakening the IF2-fMet-tRNA Interaction Suppresses the Lethal Phenotype Caused by GTPase Inactivation.

  • Authors : Tomsic J; Laboratory of Genetics, Department of Bioscience and Biotechnology, University of Camerino, 62032 Camerino, Italy.; City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA.

Subjects: Genes, Lethal*; Escherichia coli/Escherichia coli/Escherichia coli/*growth & development ; GTP Phosphohydrolases/GTP Phosphohydrolases/GTP Phosphohydrolases/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 08; Vol. 22 (24). Date of Electronic Publication: 2021 Dec 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Pre-selection against a lethal recessive allele in breeding schemes with optimum-contribution selection or truncation selection.

  • Authors : Hjortø L; Center for Quantitative Genetics and Genomics, Aarhus University, Blichers Allé 20, 8830 Tjele, Denmark. .; SEGES, Agro Food Park 15, 8200 Aarhus N, Denmark. .

Subjects: Alleles* ; Breeding* ; Genes, Lethal*

  • Source: Genetics, selection, evolution : GSE [Genet Sel Evol] 2021 Sep 22; Vol. 53 (1), pp. 75. Date of Electronic Publication: 2021 Sep 22.Publisher: BioMed Central Country of Publication: France NLM ID: 9114088 Publication Model: Electronic Cited Medium: Internet ISSN: 1297-9686

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Academic Journal

Embryonic Lethal Phenotyping to Identify Candidate Genes Related with Birth Defects.

  • Authors : Yan B; State Key Laboratory of Genetic Engineering and National Center for International Research of Development and Disease, Institute of Developmental Biology and Molecular Medicine, Collaborative Innovation Center of Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200441, China.; Gong B

Subjects: Phenotype* ; Congenital Abnormalities*/Congenital Abnormalities*/Congenital Abnormalities*/genetics ; Congenital Abnormalities*/Congenital Abnormalities*/Congenital Abnormalities*/pathology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 13; Vol. 25 (16). Date of Electronic Publication: 2024 Aug 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Two Nicotiana occidentalis accessions enable gene identification for Type II hybrid lethality by the cross to N. sylvestris.

  • Authors : Kawaguchi K; Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Osaka, 599-8531, Japan.; NARO Hokkaido Agricultural Research Center, Memuro Research Station, 9-4 Shinsei-minami, Memuro, Kasai, Hokkaido, 082-0081, Japan.

Subjects: Genes, Lethal* ; Hybridization, Genetic*; Nicotiana/Nicotiana/Nicotiana/*genetics

  • Source: Scientific reports [Sci Rep] 2021 Aug 24; Vol. 11 (1), pp. 17093. Date of Electronic Publication: 2021 Aug 24.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 ل  979 نتائج ل ""Genes, Lethal""