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Academic Journal

Controlled Exit from the G2/M Checkpoint in RPE-1 Cells Using RO3306: Enrichment of Phase-Specific Cell Populations for In-Depth Analyses of Mitotic Events.

Authors : Anglada T; Department of Cell Biology, Physiology, and Immunology, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain.; Pulido-Artola N

Subjects: Mitosis*/Mitosis*/Mitosis*/drug effects ; G2 Phase Cell Cycle Checkpoints*/G2 Phase Cell Cycle Checkpoints*/G2 Phase Cell Cycle Checkpoints*/drug effects ; Retinal Pigment Epithelium*/Retinal Pigment Epithelium*/Retinal Pigment Epithelium*/cytology

Source: International journal of molecular sciences [Int J Mol Sci] 2025 May 21; Vol. 26 (10). Date of Electronic Publication: 2025 May 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Apoptosis and G2/M Phase Cell Cycle Arrest Induced by Alkaloid Erythraline Isolated from Erythrina velutina in SiHa Cervical Cancer Cell.

Authors : Miranda CAN; Postgraduate Program in Development and Technological Innovation in Medicines, Federal University of Rio Grande do Norte, Natal 52171-900, RN, Brazil.; Souza ATB

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Uterine Cervical Neoplasms*/Uterine Cervical Neoplasms*/Uterine Cervical Neoplasms*/drug therapy ; Uterine Cervical Neoplasms*/Uterine Cervical Neoplasms*/Uterine Cervical Neoplasms*/metabolism

Source: International journal of molecular sciences [Int J Mol Sci] 2025 May 12; Vol. 26 (10). Date of Electronic Publication: 2025 May 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Lithium Induces Oxidative Stress, Apoptotic Cell Death, and G2/M Phase Cell Cycle Arrest in A549 Lung Cancer Cells.

Authors : Ramushu P; Department of Biochemistry, Microbiology and Biotechnology, Faculty of Science and Agriculture, University of Limpopo, P/bag x1106, Sovenga 0727, South Africa.; Mangoakoane DD

Subjects: Oxidative Stress*/Oxidative Stress*/Oxidative Stress*/drug effects ; Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/metabolism

Source: Molecules (Basel, Switzerland) [Molecules] 2025 Apr 17; Vol. 30 (8). Date of Electronic Publication: 2025 Apr 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

G2M-checkpoint related immune barrier structure and signature for prognosis and immunotherapy response in hepatocellular carcinoma: insights from spatial transcriptome and machine learning.

Authors : Chen X; Department of Radiation Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.; Wu S

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/genetics ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/immunology ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/therapy

Source: Journal of translational medicine [J Transl Med] 2025 Feb 18; Vol. 23 (1), pp. 202. Date of Electronic Publication: 2025 Feb 18.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Academic Journal

The HIV-1 vpr R77Q Mutant Induces Apoptosis, G 2 Cell Cycle Arrest, and Lower Production of Pro-Inflammatory Cytokines in Human CD4+ T Cells.

Authors : Solis-Leal A; Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.; Karlinsey DC

Subjects: vpr Gene Products, Human Immunodeficiency Virus*/vpr Gene Products, Human Immunodeficiency Virus*/vpr Gene Products, Human Immunodeficiency Virus*/genetics ; vpr Gene Products, Human Immunodeficiency Virus*/vpr Gene Products, Human Immunodeficiency Virus*/vpr Gene Products, Human Immunodeficiency Virus*/metabolism ; CD4-Positive T-Lymphocytes*/CD4-Positive T-Lymphocytes*/CD4-Positive T-Lymphocytes*/virology

Source: Viruses [Viruses] 2024 Oct 21; Vol. 16 (10). Date of Electronic Publication: 2024 Oct 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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Academic Journal

The Induction of G2/M Phase Cell Cycle Arrest and Apoptosis by the Chalcone Derivative 1C in Sensitive and Resistant Ovarian Cancer Cells Is Associated with ROS Generation.

Authors : Salanci Š; Department of Pharmacology, Faculty of Medicine, Pavol Jozef Šafárik University, 040 01 Košice, Slovakia.; Vilková M

Subjects: Reactive Oxygen Species*/Reactive Oxygen Species*/Reactive Oxygen Species*/metabolism ; Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/metabolism

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 09; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Partial Alleviation of Homologous Superinfection Exclusion of SeMNPV Latently Infected Cells by G1 Phase Infection and G2/M Phase Arrest.

Authors : Fu QM; School of Life Sciences, Guizhou Normal University, Guiyang 550025, China.; Fang Z

Subjects: Virus Replication* ; Nucleopolyhedroviruses*/Nucleopolyhedroviruses*/Nucleopolyhedroviruses*/physiology ; Spodoptera*/Spodoptera*/Spodoptera*/virology Autographa californica multiple nuclear polyhedrosis virus

Source: Viruses [Viruses] 2024 May 06; Vol. 16 (5). Date of Electronic Publication: 2024 May 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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Academic Journal

CDK4/6 activity is required during G 2 arrest to prevent stress-induced endoreplication.

Authors : McKenney C; Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Subjects: Cyclin-Dependent Kinase 4*/Cyclin-Dependent Kinase 4*/Cyclin-Dependent Kinase 4*/metabolism ; Cyclin-Dependent Kinase 4*/Cyclin-Dependent Kinase 4*/Cyclin-Dependent Kinase 4*/genetics ; Cyclin-Dependent Kinase 6*/Cyclin-Dependent Kinase 6*/Cyclin-Dependent Kinase 6*/metabolism

Source: Science (New York, N.Y.) [Science] 2024 May 03; Vol. 384 (6695), pp. eadi2421. Date of Electronic Publication: 2024 May 03.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic

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Academic Journal

Quercetin triggers cell apoptosis-associated ROS-mediated cell death and induces S and G2/M-phase cell cycle arrest in KON oral cancer cells.

Authors : Tubtimsri S; Division of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Burapha University, Chonburi, Thailand.; Chuenbarn T

Subjects: Quercetin*/Quercetin*/Quercetin*/pharmacology ; Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Mouth Neoplasms*/Mouth Neoplasms*/Mouth Neoplasms*/drug therapy

Source: BMC complementary medicine and therapies [BMC Complement Med Ther] 2025 Jan 30; Vol. 25 (1), pp. 34. Date of Electronic Publication: 2025 Jan 30.Publisher: BioMed Central Country of Publication: England NLM ID: 101761232 Publication Model: Electronic Cited Medium: Internet ISSN: 2662-7671

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Academic Journal

The Proapoptotic Effect of MB-653 Is Associated with the Modulation of Metastasis and Invasiveness-Related Signalling Pathways in Human Colorectal Cancer Cells.

Authors : Sokoli L; Department of Pharmacology and Toxicology, University of Veterinary Medicine and Pharmacy, Komenského 73, 041 81 Košice, Slovakia.; Department of Pharmacology, Faculty of Medicine, Pavol Jozef Šafárik University, 040 01 Košice, Slovakia.

Subjects: Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/pathology ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/metabolism ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/drug therapy

Source: Biomolecules [Biomolecules] 2025 Jan 06; Vol. 15 (1). Date of Electronic Publication: 2025 Jan 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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فلترة النتائج

Controlled Exit from the G2/M Checkpoint in RPE-1 Cells Using RO3306: Enrichment of Phase-Specific Cell Populations for In-Depth Analyses of Mitotic Events.

Apoptosis and G2/M Phase Cell Cycle Arrest Induced by Alkaloid Erythraline Isolated from Erythrina velutina in SiHa Cervical Cancer Cell.

Lithium Induces Oxidative Stress, Apoptotic Cell Death, and G2/M Phase Cell Cycle Arrest in A549 Lung Cancer Cells.

G2M-checkpoint related immune barrier structure and signature for prognosis and immunotherapy response in hepatocellular carcinoma: insights from spatial transcriptome and machine learning.

The HIV-1 vpr R77Q Mutant Induces Apoptosis, G 2 Cell Cycle Arrest, and Lower Production of Pro-Inflammatory Cytokines in Human CD4+ T Cells.

The Induction of G2/M Phase Cell Cycle Arrest and Apoptosis by the Chalcone Derivative 1C in Sensitive and Resistant Ovarian Cancer Cells Is Associated with ROS Generation.

Partial Alleviation of Homologous Superinfection Exclusion of SeMNPV Latently Infected Cells by G1 Phase Infection and G2/M Phase Arrest.

CDK4/6 activity is required during G 2 arrest to prevent stress-induced endoreplication.

Quercetin triggers cell apoptosis-associated ROS-mediated cell death and induces S and G2/M-phase cell cycle arrest in KON oral cancer cells.

The Proapoptotic Effect of MB-653 Is Associated with the Modulation of Metastasis and Invasiveness-Related Signalling Pathways in Human Colorectal Cancer Cells.

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