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In silico analyses of Wnt1 nsSNPs reveal structurally destabilizing variants, altered interactions with Frizzled receptors and its deregulation in tumorigenesis.

• Authors : Mondal A; Department of Physiology, Katwa College, Purba Bardhaman, Katwa, West Bengal, 713130, India.; Department of Molecular Biology and Biotechnology, University of Kalyani, Nadia, Kalyani, India.

Subjects: Frizzled Receptors*/Frizzled Receptors*/Frizzled Receptors*/genetics ; Polymorphism, Single Nucleotide*; Wnt1 Protein/Wnt1 Protein/Wnt1 Protein/*genetics

• Source: Scientific reports [Sci Rep] 2022 Sep 02; Vol. 12 (1), pp. 14934. Date of Electronic Publication: 2022 Sep 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Integrin-linked kinase-frizzled 7 interaction maintains cancer stem cells to drive platinum resistance in ovarian cancer.

• Authors : Atwani R; Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN, 46202, USA.

Subjects: Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/drug therapy ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/pathology ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/metabolism

• Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Jun 01; Vol. 43 (1), pp. 156. Date of Electronic Publication: 2024 Jun 01.Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966

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E3 ligases RNF43 and ZNRF3 display differential specificity for endocytosis of Frizzled receptors

• Authors : Bugter, Jeroen M; van Kerkhof, Peter; Jordens, Ingrid ...

Subjects: Down-Regulation/genetics; Endocytosis/genetics; Frizzled Receptors/metabolism

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In silico analyses of Wnt1 nsSNPs reveal structurally destabilizing variants, altered interactions with Frizzled receptors and its deregulation in tumorigenesis

• Authors : Amalesh Mondal; Debarati Paul; Shubhra Ghosh Dastidar

Subjects: Medicine; Science

• Source: Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)

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Frizzled Receptors as Potential Therapeutic Targets in Human Cancers.

• Authors : Zeng CM; Guangdong Key Laboratory for Genome Stability & Disease Prevention, Department of Pharmacology and Carson International Cancer Research Centre, Shenzhen University School of Medicine, Shenzhen 518060, China. .; Chen Z

Subjects: Frizzled Receptors/Frizzled Receptors/Frizzled Receptors/*metabolism ; Neoplasms/Neoplasms/Neoplasms/*metabolism; Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/immunology

• Source: International journal of molecular sciences [Int J Mol Sci] 2018 May 22; Vol. 19 (5). Date of Electronic Publication: 2018 May 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Signaling Specificity by Frizzled Receptors in Drosophila

• Authors : Boutros, Michael; Mihaly, Jozsef; Bouwmeester, Tewis

• Source: Science, 2000 Jun 01. 288(5472), 1825-1828.

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Frizzled receptors in melanomagenesis: From molecular interactions to target identification

• Authors : Sheikh A. Umar; Bo Dong; Minakshi Nihal

Subjects: frizzled; Wnt/β-catenin signaling; planar cell polarity

• Source: Frontiers in Oncology, Vol 12 (2022)

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Expression of the Frizzled receptors and their co-receptors in calcified human aortic valves.

• Authors : Siddique A; a Cardiology, Cardiac Surgery and Pathology, McGill University Health Centre, Montreal, QC H4A 3J1, Canada.; Yu B

Subjects: Aortic Valve/Aortic Valve/Aortic Valve/*metabolism ; Aortic Valve/Aortic Valve/Aortic Valve/*pathology ; Aortic Valve Stenosis/Aortic Valve Stenosis/Aortic Valve Stenosis/*genetics Aortic Valve, Calcification of

• Source: Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2018 Feb; Vol. 96 (2), pp. 208-214. Date of Electronic Publication: 2017 Dec 15.Publisher: Canadian Science Publishing Country of Publication: Canada NLM ID: 0372712 Publication Model: Print-Electronic Cited Medium: Internet

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Cancer chemoprevention through Frizzled receptors and EMT

• Authors : K. Sompel; A. Elango; A. J. Smith

Subjects: Frizzled; Chemoprevention; Cancer

• Source: Discover Oncology, Vol 12, Iss 1, Pp 1-15 (2021)

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Follistatin-like 1 (FSTL1) interacts with Wnt ligands and Frizzled receptors to enhance Wnt/beta-catenin signaling in obstructed kidneys in vivo

Subjects: ddc:no; doc-type:article; publishedVersion

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