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Establishing Trypanosoma cruzi farnesyl pyrophosphatesynthase as a viable target for biosensor driven fragment-based lead discovery

• Authors : Opassi, Giulia, 1988; Nordström, Helena, 1974; Lundin, Arne

Subjects: binding efficiency; Chagas disease; farnesyl pyrophosphate synthase

• Source: Protein Science. 29(4):991-1003

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1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery

• Authors : Claire Raingeval; Olivier Cala; Béatrice Brion

Subjects: waterlogsy; solvent-exposed; saturation transfer difference

• Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1218-1225 (2019)

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Crystal polymorphism in fragment-based lead discovery of ligands of the catalytic domain of UGGT, the glycoprotein folding quality control checkpoint

• Authors : Alessandro T. Caputo; Roberta Ibba; James D. Le Cornu

Subjects: UGGT; crystal polymorphism; structure-based lead discovery

• Source: Frontiers in Molecular Biosciences, Vol 9 (2022)

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1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery.

• Authors : Raingeval, Claire¹ (AUTHOR); Cala, Olivier¹ (AUTHOR); Brion, Béatrice¹ (AUTHOR)

Subjects: *GLYCOGEN phosphorylase; *MAGNETIZATION transfer; *PHOSPHORYLASES

• Source: Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2019, Vol. 34 Issue 1, p1218-1225. 8p.

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Making the most of crystal polymorphism in fragment-based lead discovery

• Authors : Caputo, AT; Ibba, R; Cornu, JD

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Fragment-Based Lead Discovery Strategies in Antimicrobial Drug Discovery

• Authors : Monika I. Konaklieva; Balbina J. Plotkin

Subjects: FBLD; antimicrobial; multidrug resistance

• Source: Antibiotics, Vol 12, Iss 2, p 315 (2023)

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Establishing Trypanosoma cruzi farnesyl pyrophosphate synthase as a viable target for biosensor driven fragment‐based lead discovery.

• Authors : Opassi, Giulia¹ (AUTHOR); Nordström, Helena^1,2 (AUTHOR); Lundin, Arne³ (AUTHOR)

• Source: Protein Science: A Publication of the Protein Society. Apr2020, Vol. 29 Issue 4, p991-1003. 13p.

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Crystal polymorphism in fragment-based lead discovery of ligands of the catalytic domain of UGGT, the glycoprotein folding quality control checkpoint

• Authors : Caputo, AT; Ibba, R; Le Cornu, JD

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Process of Fragment-Based Lead Discovery—A Perspective from NMR.

• Authors : Rongsheng Ma¹ (AUTHOR) ; Pengchao Wang¹ (AUTHOR) ; Jihui Wu¹ (AUTHOR)

• Source: Molecules. Jul2016, Vol. 21 Issue 7, p854-867. 14p. 2 Diagrams, 1 Graph.

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1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery

• Authors : Béatrice Brion; Marc Le Borgne; Roderick E. Hubbard ...

Subjects: solvent-exposed; Magnetic Resonance Spectroscopy; Stereochemistry

• Source: Journal of Enzyme Inhibition and Medicinal ChemistryJournal of Enzyme Inhibition and Medicinal Chemistry, Informa Healthcare, 2019, 34 (1), pp.1218-1225. ⟨10.1080/14756366.2019.1636235⟩

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