نتائج البحث

O -GlcNAcylation of Focal Adhesion Kinase Regulates Cell Adhesion, Migration, and Proliferation via the FAK/AKT Pathway.

• Authors : Zhang Z; Division of Regulatory Glycobiology, Graduate School of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Sendai 980-0845, Miyagi, Japan.; Isaji T

Subjects: Cell Movement* ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism ; Cell Adhesion*

• Source: Biomolecules [Biomolecules] 2024 Dec 10; Vol. 14 (12). Date of Electronic Publication: 2024 Dec 10.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Discovery of novel 2,4-diarylaminopyrimidine hydrazone derivatives as potent anti-thyroid cancer agents capable of inhibiting FAK.

• Authors : Li H; Department of Thyroid Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.; Jia MQ

Subjects: Hydrazones*/Hydrazones*/Hydrazones*/pharmacology ; Hydrazones*/Hydrazones*/Hydrazones*/chemistry ; Hydrazones*/Hydrazones*/Hydrazones*/chemical synthesis

• Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2024 Dec; Vol. 39 (1), pp. 2423875. Date of Electronic Publication: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Acetylated Globotetraose (Ac-Gb4) Suppresses Triple-Negative Breast Cancer Through FAK/AKT Signaling Pathway.

• Authors : Lee YK; Medical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, Kaohsiung 80284, Taiwan.; Institute of Medical Science and Technology, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/metabolism ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/drug therapy ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/pathology

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 12; Vol. 25 (24). Date of Electronic Publication: 2024 Dec 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Kinin Receptors B1 and B2 Mediate Breast Cancer Cell Migration and Invasion by Activating the FAK-Src Axis.

• Authors : González-Turén F; School of Nursing, Faculty of Health Sciences, Universidad Bernardo O'Higgins, Santiago 8370854, Chile.; Lobos-González L

Subjects: Receptor, Bradykinin B2*/Receptor, Bradykinin B2*/Receptor, Bradykinin B2*/metabolism ; Cell Movement*/Cell Movement*/Cell Movement*/drug effects ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/metabolism

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 31; Vol. 25 (21). Date of Electronic Publication: 2024 Oct 31.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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The Oncolytic Avian Reovirus p17 Protein Inhibits Invadopodia Formation in Murine Melanoma Cancer Cells by Suppressing the FAK/Src Pathway and the Formation of theTKs5/NCK1 Complex.

• Authors : Hsu CY; Division of Urology, Department of Surgery, Tungs' Taichung MetroHarbor Hospital, Taichung 435, Taiwan.; Ph.D. Program in Translational Medicine, National Chung Hsing University, Taichung 402, Taiwan.

Subjects: Orthoreovirus, Avian*/Orthoreovirus, Avian*/Orthoreovirus, Avian*/physiology ; Orthoreovirus, Avian*/Orthoreovirus, Avian*/Orthoreovirus, Avian*/genetics ; Signal Transduction*

• Source: Viruses [Viruses] 2024 Jul 17; Vol. 16 (7). Date of Electronic Publication: 2024 Jul 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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Adipocyte-specific FAK deletion promotes pancreatic β-cell apoptosis via adipose inflammatory response to exacerbate diabetes mellitus.

• Authors : Ding F; Department of Pharmacology, Wuhan University School of Basic Medical Sciences, Wuhan, China.; Zheng P

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/genetics ; Insulin-Secreting Cells*/Insulin-Secreting Cells*/Insulin-Secreting Cells*/metabolism ; Adipocytes*/Adipocytes*/Adipocytes*/metabolism

• Source: Clinical and translational medicine [Clin Transl Med] 2024 Jul; Vol. 14 (7), pp. e1742.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet ISSN: 2001-1326

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FAK mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation by modulating mitochondrial transcription termination factor 1/cyclin D1.

• Authors : Lin C; Department of Respiratory and Critical Care Medicine, Yueyang People's Hospital of Hunan Normal University, Yueyang, China.; Yang H

Subjects: Cyclin D1*/Cyclin D1*/Cyclin D1*/genetics ; Cyclin D1*/Cyclin D1*/Cyclin D1*/metabolism ; Pulmonary Artery*/Pulmonary Artery*/Pulmonary Artery*/metabolism

• Source: Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13767.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN:

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GTPase Regulator Associated with Focal Adhesion Kinase 1 (GRAF1) Immunoglobulin‐Associated Ataxia and Neuropathy.

• Authors : Pittock, Sean J.^1,2 (AUTHOR) ; Alfugham, Nora¹ (AUTHOR); O'Connor, Kevin² (AUTHOR)

• Source: Movement Disorders Clinical Practice. Nov2020, Vol. 7 Issue 8, p904-909. 6p.

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Integrin β4 Regulates Cell Migration of Lung Adenocarcinoma Through FAK Signaling.

• Authors : Zhang S; Hebei Province Xingtai People's Hospital Postdoctoral Workstation, Xingtai, China.; Postdoctoral Mobile Station, Hebei Medical University, Shijiazhuang, China.

Subjects: Integrin beta4*/Integrin beta4*/Integrin beta4*/metabolism ; Integrin beta4*/Integrin beta4*/Integrin beta4*/genetics ; Cell Movement*

• Source: Molecular biotechnology [Mol Biotechnol] 2025 Feb; Vol. 67 (2), pp. 496-509. Date of Electronic Publication: 2024 Feb 08.Publisher: Springer Country of Publication: Switzerland NLM ID: 9423533 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Nuclear Focal Adhesion Kinase Protects against Cisplatin Stress in Ovarian Carcinoma.

• Authors : Zhang, Yichi; Ojalill, Marjaana; Boyer, Antonia

Subjects: Biochemistry and Cell Biology; Biological Sciences; Cancer

• Source: Cancer Research Communications. 4(12)

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