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Phase II Trial of Pemigatinib in Combination With Atezolizumab and Bevacizumab for Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion

• Authors : Incyte Corporation; Genentech, Inc.

• Source: Phase II Trial of Pemigatinib in Combination With Atezolizumab and Bevacizumab for Treatment of Advanced Cholangiocarcinoma With FGFR2

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Study of Futibatinib in Patients With Advanced Cholangiocarcinoma With FGFR2 Fusion or Rearrangement (FOENIX-CCA4)

• Source: Phase 2 Study of Futibatinib 20 mg and 16 mg in Patients With Advanced Cholangiocarcinoma With FGFR2 Fusions or Rearrangements

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Persistent response to combination therapy of pemigatinib and chemotherapy in a child of combined hepatocellular-cholangiocarcinoma with FGFR2 fusion.

• Authors : He, Guo-qian^1,2 (AUTHOR); Li, Qing³ (AUTHOR); Jing, Xiao-yu^1,2 (AUTHOR)

• Source: Molecular Cancer. 12/6/2024, Vol. 23 Issue 1, p1-7. 7p.

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Persistent response to combination therapy of pemigatinib and chemotherapy in a child of combined hepatocellular-cholangiocarcinoma with FGFR2 fusion

• Authors : Guo-qian He; Qing Li; Xiao-yu Jing

Subjects: Hepatoblastoma, Children, combined hepatocellular-cholangiocarcinoma; Hepatocellular carcinoma; Cholangiocarcinoma

• Source: Molecular Cancer, Vol 23, Iss 1, Pp 1-7 (2024)

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Prolonged Clinical Benefit with Futibatinib in a Patient with FGFR Inhibitor–Pretreated FGFR2 Fusion–Positive Intrahepatic Cholangiocarcinoma: Case Report.

• Authors : d'Arienzo, Paolo D (AUTHOR); MacDonald, Alan R (AUTHOR); Patel, Virjen (AUTHOR)

• Source: OncoTargets & Therapy. Jun2024, Vol. 17, p489-496. 8p.

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Pemigatinib combined with immunotherapy and stereotactic body radiation therapy for FGFR2 fusion-positive advanced intrahepatic cholangiocarcinoma with brain metastasis: a Case Report

• Authors : Jiamin Guo; Lingqi Sun; Ye Chen

Subjects: intrahepatic cholangiocarcinoma; FGFR2-fusion; brain metastasis

• Source: Frontiers in Pharmacology, Vol 15 (2024)

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Pemigatinib After Curative Local Therapy in Advanced iCCA With FGFR2 Fusion/Rearrangements

• Authors : Incyte Biosciences International Sàrl

• Source: A Phase II Study of Pemigatinib After Curative Local Therapy in Locally Advanced Intrahepatic Cholangiocarcinoma (iCCA) Harboring FGFR2 Fusions/Rearrangements.

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Phase Ib Trial of Infigratinib In Combination With Atezolizumab And Bevacizumab for The Second-Line Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion/Amplification

• Authors : Helsinn Healthcare SA

• Source: Phase Ib Trial of Infigratinib In Combination With Atezolizumab And Bevacizumab for The Second-Line Treatment of Advanced Cholangiocarcinoma With FGFR2

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A DNA/RNA heteroduplex oligonucleotide coupling asparagine depletion restricts FGFR2 fusion-driven intrahepatic cholangiocarcinoma

• Authors : Zhenzhen Chu; Baohuan Zhang; Xuxuan Zhou

Subjects: MT: Oligonucleotides: Therapies and Applications; intrahepatic cholangiocarcinoma; FGFR2 fusion mutations

• Source: Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102047- (2023)

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EGFR Inhibition Potentiates FGFR Inhibitor Therapy and Overcomes Resistance in FGFR2 Fusion–Positive Cholangiocarcinoma

• Authors : Wu, Qibiao; Zhen, Yuanli; Shi, Lei

Subjects: Digestive Diseases - (Gallbladder); Digestive Diseases; 6.1 Pharmaceuticals

• Source: Cancer Discovery. 12(5)

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