نتائج البحث

Soluble Epoxide Hydrolase Inhibition Attenuates Proteinuria by Alleviating Renal Inflammation and Podocyte Injuries in Adriamycin-Induced Nephropathy.

• Authors : Niu, Qingyu¹ (AUTHOR) ; Guo, Ziyu¹ (AUTHOR); Liang, Yaoxian¹ (AUTHOR)

Subjects: *KIDNEY glomerulus diseases; *EPOXIDE hydrolase; *KIDNEY tubules

• Source: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10629. 11p.

تفاصيل العنوان

Preclinical Evaluation of Soluble Epoxide Hydrolase Inhibitor AMHDU against Neuropathic Pain.

• Authors : Babkov, Denis¹ (AUTHOR) ; Eliseeva, Natalya¹ (AUTHOR) ; Adzhienko, Kristina¹ (AUTHOR)

Subjects: *EPOXIDE hydrolase; *NEURALGIA; *DIABETIC neuropathies

• Source: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 16, p8841. 9p.

تفاصيل العنوان

Upregulated Nuclear Expression of Soluble Epoxide Hydrolase Predicts Poor Outcome in Breast Cancer Patients: Importance of the Digital Pathology Approach.

• Authors : Montecillo-Aguado, Mayra¹ (AUTHOR) ; Soca-Chafre, Giovanny¹ (AUTHOR) ; Antonio-Andres, Gabriela¹ (AUTHOR)

Subjects: *TRIPLE-negative breast cancer; *EPOXIDE hydrolase; *UNSATURATED fatty acids

• Source: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 15, p8024. 15p.

تفاصيل العنوان

The Inhibition Activity of Natural Methoxyflavonoid from Inula britannica on Soluble Epoxide Hydrolase and NO Production in RAW264.7 Cells.

• Authors : Kim, Jang Hoon¹ (AUTHOR) ; Han, Kyung-Sook¹ (AUTHOR) ; Lee, Eun-Song¹ (AUTHOR)

Subjects: *EPOXIDE hydrolase; *COMPUTATIONAL chemistry; *OXIDATIVE stress

• Source: International Journal of Molecular Sciences. Apr2024, Vol. 25 Issue 8, p4357. 11p.

تفاصيل العنوان

Novel molecular mechanism driving neuroprotection after soluble epoxide hydrolase inhibition: Insights for Alzheimer's disease therapeutics.

• Authors : Griñán‐Ferré, Christian^1,2 (AUTHOR); Jarné‐Ferrer, Júlia¹ (AUTHOR); Bellver‐Sanchís, Aina¹ (AUTHOR)

• Source: CNS Neuroscience & Therapeutics. Apr2024, Vol. 30 Issue 4, p1-20. 20p.

تفاصيل العنوان

1,3-Dichloroadamantyl-Containing Ureas as Potential Triple Inhibitors of Soluble Epoxide Hydrolase, p38 MAPK and c-Raf.

• Authors : Gladkikh, Boris P.¹ (AUTHOR) ; Danilov, Dmitry V.¹ (AUTHOR) ; D'yachenko, Vladimir S.^1,2 (AUTHOR)

Subjects: *EPOXIDE hydrolase; *MITOGEN-activated protein kinases; *INFLAMMATORY mediators

• Source: International Journal of Molecular Sciences. Jan2024, Vol. 25 Issue 1, p338. 29p.

تفاصيل العنوان

Evaluation of the Therapeutic Potential of Sulfonyl Urea Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors.

• Authors : Kundu B; Section on Medicinal Chemistry, National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institutes of Health (NIH), 5625 Fishers Lane, Rockville, MD 20852, USA.; Dvorácskó S

Subjects: Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/antagonists & inhibitors ; Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/metabolism ; Urea*/Urea*/Urea*/pharmacology

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Jun 26; Vol. 29 (13). Date of Electronic Publication: 2024 Jun 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

تفاصيل العنوان

Fluorine and chlorine substituted adamantyl-urea as molecular tools for inhibition of human soluble epoxide hydrolase with picomolar efficacy.

• Authors : Burmistrov, Vladimir V.^1,2,3 (AUTHOR); Morisseau, Christophe² (AUTHOR); Danilov, Dmitry V.¹ (AUTHOR)

Subjects: *EPOXIDE hydrolase; *CHLORINE; *FLUORINE

• Source: Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2023, Vol. 38 Issue 1, p1-7. 7p.

تفاصيل العنوان

Insights into the inhibitory activities of neolignans and diarylnonanoid derivatives from nutmeg (Myristica fragrans Houtt.) seeds on soluble epoxide hydrolase using in vitro and in silico approaches.

• Authors : Oanh, Vu Thi^1,2 (AUTHOR); Phong, Nguyen Viet^1,3 (AUTHOR); Min, Byung Sun⁴ (AUTHOR)

Subjects: *NUTMEG tree; *EPOXIDE hydrolase; *NEOLIGNANS

• Source: Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2023, Vol. 38 Issue 1, p1-15. 15p.

تفاصيل العنوان

Enhancing cancer immunotherapy via inhibition of soluble epoxide hydrolase

• Authors : Kelly, Abigail G; Wang, Weicang; Rothenberger, Eva

Subjects: Biomedical and Clinical Sciences; Oncology and Carcinogenesis; Immunology

• Source: Proceedings of the National Academy of Sciences of the United States of America. 121(7)

تفاصيل العنوان