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Evaluation of nonnatural L-iminosugar C,C-glycosides, a new class of C-branched iminosugars, as glycosidase inhibitors

• Authors : Désiré, Jérôme; Debbah, Zakaria; Gueyrard, David ...

Subjects: iminosugar; glycosidases; glycomimetics

• Source: ISSN: 0008-6215.

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Synthesis, conformational analysis and glycosidase inhibition of bicyclic nojirimycin C-glycosides based on an octahydrofuro[3,2-b]pyridine motif

• Authors : Désiré, Jérôme; Foucart, Quentin; Poveda, Ana ...

Subjects: hexosaminidase; iminosugar; glycosidase

• Source: ISSN: 0008-6215.

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Sugar-Derived Amidines and Congeners: Structures, Glycosidase Inhibition and Applications

• Authors : Blériot, Yves; Auberger, Nicolas; Désiré, Jérôme ...

Subjects: MESH: Amidines* / chemistry; MESH: Amidines* / pharmacology; MESH: Carbohydrates

• Source: ISSN: 0929-8673.

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Structure-based optimization of type III indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors.

• Authors : Röhrig, U.F.; Majjigapu, S.R.; Vogel, P.

Subjects: Enzyme Inhibitors/chemistry; Enzyme Inhibitors/pharmacology; Heme

• Source: Journal of enzyme inhibition and medicinal chemistry, vol. 37, no. 1, pp. 1773-1811

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Development of [18F]AldoView as the First Highly Selective Aldosterone Synthase PET Tracer for Imaging of Primary Hyperaldosteronism.

• Authors : Sander, Kerstin; Gendron, Thibault; Cybulska, Klaudia A

Subjects: Fluorine Radioisotopes; Fluorine-18; Cytochrome P-450 CYP11B2/analysis

• Source: Journal of Medicinal Chemistry, 64 (13), 9321 - 9329 (2021-07-08)

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Racemases and epimerases operating through a 1,1-proton transfer mechanism:reactivity, mechanism and inhibition

• Authors : Lloyd, Matthew D; Yevglevskis, Maksims; Nathubhai, Amit

Subjects: Allosteric Regulation; Biocatalysis; Catalytic Domain

• Source: Lloyd , M D , Yevglevskis , M , Nathubhai , A , James , T D , Threadgill , M D & Woodman , T J 2021 , ' Racemases and epimerases operating through a 1,1-proton transfer mechanism : reactivity,

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Structure-based modification of pyrazolone derivatives to inhibit mTORC1 by targeting the leucyl-tRNA synthetase-RagD interaction

• Authors : Jae Hyun Kim; Kilsoo Jung; Chulho Lee

Subjects: Cell Line; Cell Survival / drug effects; Dose-Response Relationship

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A versatile stereocontrolled synthesis of 2-deoxyiminosugar C -glycosides and their evaluation as glycosidase inhibitors

• Authors : Lumbroso, Alexandre; Berthonneau, Clément; Beaudet, Isabelle ...

Subjects: C-glycoside; Enzyme Inhibitors; Glycosides

• Source: ISSN: 1477-0520.

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Melanin as a target for melanoma chemotherapy: pro-oxidant effect of oxygen and metals on melanoma viability.

• Authors : Farmer, Patrick J; Gidanian, Shirley; Shahandeh, Babbak

Subjects: Cell Line; Tumor; Cell Survival

• Source: Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society. 16(3)

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Stimulation of Heat Shock Protein 90 Chaperone Function Through Binding of a Novobiocin Analog KU-32

• Authors : Chatterjee, Bhaskar K; Jayaraj, Abhilash; Kumar, Vinay

Subjects: KU-32; allosteric modulation; chaperone-assisted protein folding

• Source: Faculty Publications

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