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  • 1-10 ل  10,993 نتائج ل ""Drug Evaluation, Preclinical""

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Academic Journal

Development of Fusion-Based Assay as a Drug Screening Platform for Nipah Virus Utilizing Baculovirus Expression Vector System.

  • Authors : Sari IP; Institute of Molecular Medicine, College of Life Science, National Tsing Hua University, Hsinchu 30013, Taiwan.; Department of Bioscience Technology, Chung Yuan Christian University, Chung-Li, Taoyuan City 320314, Taiwan.

Subjects: Nipah Virus*/Nipah Virus*/Nipah Virus*/genetics ; Nipah Virus*/Nipah Virus*/Nipah Virus*/drug effects ; Baculoviridae*/Baculoviridae*/Baculoviridae*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 22; Vol. 25 (16). Date of Electronic Publication: 2024 Aug 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Discovery of Antibacterial Compounds with Potential Multi-Pharmacology against Staphylococcus Mur ligase Family Members by In Silico Structure-Based Drug Screening.

  • Authors : Teshima M; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, Iizuka 820-8502, Japan.; Monobe K

Subjects: Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/pharmacology ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/chemistry ; Staphylococcus aureus*/Staphylococcus aureus*/Staphylococcus aureus*/drug effects

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Aug 10; Vol. 29 (16). Date of Electronic Publication: 2024 Aug 10.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Remyelinating Drugs at a Crossroad: How to Improve Clinical Efficacy and Drug Screenings.

  • Authors : Al Jaf AIA; Department of Biology, University of Rome 'Tor Vergata', Via della Ricerca Scientifica 1, 00133 Rome, Italy.; Peria S

Subjects: Remyelination*/Remyelination*/Remyelination*/drug effects ; Drug Evaluation, Preclinical*; Humans

  • Source: Cells [Cells] 2024 Aug 08; Vol. 13 (16). Date of Electronic Publication: 2024 Aug 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Advancing Cardiovascular Drug Screening Using Human Pluripotent Stem Cell-Derived Cardiomyocytes.

  • Authors : Oh J; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDI Hub), Daegu 41061, Republic of Korea.; Kwon OB

Subjects: Myocytes, Cardiac*/Myocytes, Cardiac*/Myocytes, Cardiac*/drug effects ; Myocytes, Cardiac*/Myocytes, Cardiac*/Myocytes, Cardiac*/metabolism ; Myocytes, Cardiac*/Myocytes, Cardiac*/Myocytes, Cardiac*/cytology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 21; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Human Hepatobiliary Organoids: Recent Advances in Drug Toxicity Verification and Drug Screening.

  • Authors : Fang H; Department of Pathology and Pathophysiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China.; Jinan Microecological Biomedicine Shandong Laboratory, Jinan 250117, China.

Subjects: Organoids*/Organoids*/Organoids*/drug effects ; Organoids*/Organoids*/Organoids*/pathology ; Drug Evaluation, Preclinical*/Drug Evaluation, Preclinical*/Drug Evaluation, Preclinical*/methods

  • Source: Biomolecules [Biomolecules] 2024 Jul 04; Vol. 14 (7). Date of Electronic Publication: 2024 Jul 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

ACFIS 2.0: an improved web-server for fragment-based drug discovery via a dynamic screening strategy.

  • Authors : Shi XX; National Key Laboratory of Green Pesticide, Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, Central China Normal University, Wuhan430079, P.R. China.; Wang ZZ

Subjects: Drug Discovery*/Drug Discovery*/Drug Discovery*/instrumentation ; Drug Discovery*/Drug Discovery*/Drug Discovery*/methods ; Data Visualization*

  • Source: Nucleic acids research [Nucleic Acids Res] 2023 Jul 05; Vol. 51 (W1), pp. W25-W32.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Breeze 2.0: an interactive web-tool for visual analysis and comparison of drug response data.

  • Authors : Potdar S; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Finland.; Ianevski F

Subjects: Drug Evaluation, Preclinical* ; Software*; Computer Graphics

  • Source: Nucleic acids research [Nucleic Acids Res] 2023 Jul 05; Vol. 51 (W1), pp. W57-W61.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

An animal-free preclinical drug screening platform based on human precision-cut kidney slices.

  • Authors : Mutsaers HAM; Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 99, Aarhus N, 8200, Denmark. .; Jensen MS

Subjects: Drug Evaluation, Preclinical*/Drug Evaluation, Preclinical*/Drug Evaluation, Preclinical*/methods ; Kidney Diseases*/Kidney Diseases*/Kidney Diseases*/drug therapy ; Renal Insufficiency, Chronic*

  • Source: BMC research notes [BMC Res Notes] 2023 Mar 20; Vol. 16 (1), pp. 39. Date of Electronic Publication: 2023 Mar 20.Publisher: Biomed Central Country of Publication: England NLM ID: 101462768 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-0500

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Academic Journal

Predicting human cardiac QT alterations and pro-arrhythmic effects of compounds with a 3D beating heart-on-chip platform.

  • Authors : Visone R; Department of Electronics, Information and Bioengineering, Politecnico di Milano, Milan, 20133, Italy.; BiomimX Srl, Milan, 20158, Italy.

Subjects: Drug Evaluation, Preclinical*/Drug Evaluation, Preclinical*/Drug Evaluation, Preclinical*/methods ; Induced Pluripotent Stem Cells* ; Long QT Syndrome*/Long QT Syndrome*/Long QT Syndrome*/chemically induced

  • Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2023 Jan 31; Vol. 191 (1), pp. 47-60.Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Screening novel antiviral compounds to treat Clostridioides difficile infections.

  • Authors : Stolz BJ; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America.; Center for One Health Research, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America.

Subjects: Clostridioides difficile*/Clostridioides difficile*/Clostridioides difficile*/drug effects ; Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/pharmacology ; Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/therapeutic use

  • Source: PloS one [PLoS One] 2024 Dec 13; Vol. 19 (12), pp. e0309624. Date of Electronic Publication: 2024 Dec 13 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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  • 1-10 ل  10,993 نتائج ل ""Drug Evaluation, Preclinical""