نتائج البحث

Rare Germline Variants in DNA Repair Genes Detected in BRCA -Negative Finnish Patients with Early-Onset Breast Cancer.

• Authors : Kurkilahti, Viivi¹ (AUTHOR) ; Rathinakannan, Venkat Subramaniam¹ (AUTHOR); Nynäs, Erja² (AUTHOR)

• Source: Cancers. Sep2024, Vol. 16 Issue 17, p2955. 20p.

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Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

• Source: A Phase 1 Study of the Polymerase Theta Inhibitor Novobiocin in BRCA-Mutant and Other DNA Damage Repair-Deficient Solid Tumors

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Polymorphisms of DNA Repair Genes in Thyroid Cancer.

• Authors : Gielecińska, Adrianna^1,2 (AUTHOR) ; Kciuk, Mateusz^1,2 (AUTHOR) ; Kołat, Damian^3,4 (AUTHOR)

Subjects: *THYROID cancer; *DNA repair; *GENETIC polymorphisms

• Source: International Journal of Molecular Sciences. Jun2024, Vol. 25 Issue 11, p5995. 33p.

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Clinical relevance of protein-truncating variants of germline DNA repair genes in prostate cancer.

• Authors : Shao, Yu-Hsuan Joni^1,2 (AUTHOR); Liao, Cai-Sian³ (AUTHOR); Hsu, Yu-Ching^3,4 (AUTHOR)

• Source: BMC Cancer. 10/25/2024, Vol. 24 Issue 1, p1-9. 9p.

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Germline Sequencing DNA Repair Genes in 5545 Men With Aggressive and Nonaggressive Prostate Cancer

• Authors : Darst, BF; Dadaev, T; Saunders, E

Subjects: Medicin och hälsovetenskap

• Source: Journal of the National Cancer Institute. 113(5):616-625

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Clinical relevance of protein-truncating variants of germline DNA repair genes in prostate cancer

• Authors : Yu-Hsuan Joni Shao; Cai-Sian Liao; Yu-Ching Hsu

Subjects: Protein-truncating variant; Germline mutation; DNA repair gene

• Source: BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024)

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Author Correction: KHSRP has oncogenic functions and regulates the expression and alternative splicing of DNA repair genes in breast cancer MDA-MB-231 cells

• Authors : Xuelaiti Paizula; Aliya Wulaying; Dong Chen

Subjects: Medicine; Science

• Source: Scientific Reports, Vol 14, Iss 1, Pp 1-3 (2024)

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KHSRP has oncogenic functions and regulates the expression and alternative splicing of DNA repair genes in breast cancer MDA-MB-231 cells

• Authors : Xuelaiti Paizula; Aliya Wulaying; Dong Chen

Subjects: Breast cancer; KHSRP; RNA-seq

• Source: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

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Uncovering the clinical relevance of unclassified variants in DNA repair genes: a focus on BRCA negative Tunisian cancer families

• Authors : Maroua Boujemaa; Fatma Nouira; Nouha Jandoubi

Subjects: variants of uncertain significance; clinical relevance; DNA repair genes

• Source: Frontiers in Genetics, Vol 15 (2024)

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Combination Therapy in Cancers With Mutations in DNA Repair Genes

• Authors : GlaxoSmithKline; Pamela Munster, Principal Investigator

• Source: Combination Therapy of Niraparib and Irinotecan in Cancers With Mutations in DNA Repair Genes

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