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Difluoromethylornithine (DFMO) and AMXT-1501 for Neuroblastoma, CNS Tumors, and Sarcomas

• Authors : Aminex Therapeutics, Inc.; Giselle Sholler, Beat Childhood Cancer Chair

• Source: A Dose Escalation Study Using Difluoromethylornithine (DFMO) and AMXT-1501 Followed by a Randomized Controlled Trial of DFMO With or

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Oral AMXT 1501 Dicaprate in Combination With IV DFMO

• Source: A Phase 1B/2A Study of the Safety, Tolerability and Initial Efficacy of Oral AMXT 1501 Dicaprate and Intravenous Difluoromethylornithine (DFMO) in Patients With Cancer

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Topical Diclofenac and Topical DFMO Chemoprevention Trial in Subjects with a History of Skin Cancer

• Authors : National Cancer Institute (NCI); National Institutes of Health (NIH); Craig Elmets, Professor

• Source: A Randomized, Placebo-controlled, Double-blind, Phase II Chemoprevention Clinical Trial of Topical Diclofenac and DFMO in Subjects with a History of Skin Cancer

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Targeting ODC as an Immunotherapeutic Target in STK11 (LKB1) Pathway-Deficient NSCLC (DFMO)

• Source: Targeting ODC as an Immunotherapeutic Target in STK11 (LKB1) Pathway-Deficient NSCLC

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Study of Difluoromethylornithine (DFMO) in Combination With Bortezomib for Relapsed or Refractory Neuroblastoma

• Authors : Beat NB Cancer Foundation; Because of Ezra; K C Pharmaceuticals Inc. ...

• Source: A Phase I/II Trial of DFMO in Combination With Bortezomib in Patients With Relapsed or Refractory Neuroblastoma

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Preventative Trial of Difluoromethylornithine (DFMO) in High Risk Patients With Neuroblastoma That is in Remission

• Authors : Beat NB Cancer Foundation; Because of Ezra; K C Pharmaceuticals Inc. ...

• Source: A Phase II Preventative Trial of DFMO (Eflornithine HCl) as a Single Agent in Patients With High Risk Neuroblastoma in RemissionUrban-Wojciuk Z, Graham A, Barker

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DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma

• Authors : Giselle Sholler, Beat Childhood Cancer Chair

• Source: Phase II Trial of Eflornithine/DFMO as Maintenance Therapy for Molecular High Risk/Very High Risk and Relapsed/Refractory Medulloblastoma

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Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastoma

• Authors : K C Pharmaceuticals Inc.; Beat NB Cancer Foundation; Team Parker for Life ...

• Source: Phase II Trial of Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastoma

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Safety Study for Refractory or Relapsed Neuroblastoma With DFMO Alone and in Combination With Etoposide

• Authors : Cancer Prevention Pharmaceuticals, Inc.; University of Arizona; University of Hawaii ...

• Source: A Phase I Trial for Refractory or Relapsed Neuroblastoma With DFMO Alone and in Combination With EtoposideSaulnier Sholler GL, Gerner EW, Bergendahl G, MacArthur

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An Intermediate Expanded Use Trial of DFMO

• Authors : K C Pharmaceuticals Inc.; USWM, LLC; Giselle Sholler, Study Chair

• Source: An Intermediate Expanded Use Trial of DFMO

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