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Hepatocyte-Targeted Lipid Nanoparticle Delivery of HERC2 Plasmid Controls Drug-Induced Hepatotoxicity by Limiting β-Catenin-Regulated CYP2E1 Expression.

• Authors : Liu Y; Institute of Molecular Immunology, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, Guangdong, 510515, China.; Clinical Oncology Center, Shenzhen Key Laboratory for cancer metastasis and personalized therapy, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, 518053, China.

Subjects: Cytochrome P-450 CYP2E1*/Cytochrome P-450 CYP2E1*/Cytochrome P-450 CYP2E1*/genetics ; Cytochrome P-450 CYP2E1*/Cytochrome P-450 CYP2E1*/Cytochrome P-450 CYP2E1*/metabolism ; Hepatocytes*/Hepatocytes*/Hepatocytes*/metabolism

• Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Dec; Vol. 11 (46), pp. e2401633. Date of Electronic Publication: 2024 Oct 23.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Effects of polyphenols extracted from Keemun black tea on CYP450s activity and molecular mechanisms.

• Authors : Zuo, Dan^1,2 (AUTHOR); Lv, Le³ (AUTHOR); Ren, Hong¹ (AUTHOR)

Subjects: *GENE expression; *REPORTER genes; *LABORATORY mice

• Source: Food Science & Nutrition. Oct2024, Vol. 12 Issue 10, p7306-7315. 10p.

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A comprehensive study of CYP2E1 and its role in carcass characteristics and chemical lamb meat quality in different Indonesian sheep breeds.

• Authors : Harahap RS; Faculty of Animal Science, Post-Doctoral Animal Production and Technology Student, IPB University, Bogor, Indonesia.; Faculty of Animal Science, Jambi University, Jambi, Indonesia.

Subjects: Cytochrome P-450 CYP2E1*/Cytochrome P-450 CYP2E1*/Cytochrome P-450 CYP2E1*/genetics ; Cytochrome P-450 CYP2E1*/Cytochrome P-450 CYP2E1*/Cytochrome P-450 CYP2E1*/metabolism ; Polymorphism, Single Nucleotide*

• Source: PloS one [PLoS One] 2024 Sep 09; Vol. 19 (9), pp. e0310336. Date of Electronic Publication: 2024 Sep 09 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Hepatoprotective effects of Juglans regia on carbon tetrachloride‐induced hepatotoxicity: In silico/in vivo approach.

• Authors : Pandey, Bipindra^1,2 (AUTHOR) ; Thapa, Shankar¹ (AUTHOR); Kaundinnyayana, Atisammodavardhana² (AUTHOR)

Subjects: *CYTOCHROME P-450 CYP2E1; *LABORATORY rats; *BETULINIC acid

• Source: Food Science & Nutrition. Sep2024, Vol. 12 Issue 9, p6482-6497. 16p.

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Combinatory Effects of Acrylamide and Deoxynivalenol on In Vitro Cell Viability and Cytochrome P450 Enzymes of Human HepaRG Cells.

• Authors : Beisl, Julia¹ (AUTHOR) ; Jochum, Kristina^1,2 (AUTHOR) ; Chen, Yi³ (AUTHOR)

Subjects: *CYTOCHROME P-450; *POLLUTANTS; *GENE expression

• Source: Toxins. Sep2024, Vol. 16 Issue 9, p389. 16p.

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Astrocytes in Amyloid Generation and Alcohol Metabolism: Implications of Alcohol Use in Neurological Disorder(s).

• Authors : Kumar, Mohit¹ (AUTHOR); Swanson, Natalie¹ (AUTHOR); Ray, Sudipta¹ (AUTHOR)

• Source: Cells (2073-4409). Jul2024, Vol. 13 Issue 14, p1173. 17p.

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Different ethanol exposure durations affect cytochrome P450 2E1-mediated sevoflurane metabolism in rat liver.

• Authors : Jiang W; Department of Anesthesiology, School of Clinical Medicine of North Sichuan Medical College, Nanchong, 637000, Sichuan, China.; Zhang M

Subjects: Sevoflurane* ; Cytochrome P-450 CYP2E1*/Cytochrome P-450 CYP2E1*/Cytochrome P-450 CYP2E1*/metabolism ; Rats, Sprague-Dawley*

• Source: BMC anesthesiology [BMC Anesthesiol] 2024 Sep 10; Vol. 24 (1), pp. 321. Date of Electronic Publication: 2024 Sep 10.Publisher: BioMed Central Country of Publication: England NLM ID: 100968535 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2253

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Pharmacogenetic variability of tuberculosis biomarkers in native and mestizo Peruvian populations.

• Authors : Jaramillo‐Valverde, Luis^1,2,3 (AUTHOR) ; Levano, Kelly S.^1,4 (AUTHOR); Tarazona, David D.¹ (AUTHOR)

• Source: Pharmacology Research & Perspectives. Jun2024, Vol. 12 Issue 3, p1-10. 10p.

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Effect of SNPs in the Promoter Region on the Expression of Cytochrome P450 2E1 (CYP2E1) in Pig Liver.

• Authors : Archer, Holly¹ (AUTHOR) ; Soares, Riani A. N.¹ (AUTHOR) ; Jafarikia, Mohsen^1,2 (AUTHOR)

• Source: Animals (2076-2615). Apr2024, Vol. 14 Issue 8, p1163. 9p.

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Hepatoprotective Effect of Allium ochotense Extracts on Chronic Alcohol-Induced Fatty Liver and Hepatic Inflammation in C57BL/6 Mice.

• Authors : Go, Min Ji¹ (AUTHOR) ; Kim, Jong Min¹ (AUTHOR) ; Lee, Hyo Lim¹ (AUTHOR)

Subjects: *FATTY liver; *HEPATITIS; *HEPATIC fibrosis

• Source: International Journal of Molecular Sciences. Mar2024, Vol. 25 Issue 6, p3496. 25p.

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